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Crystallography Workshop 2019

When: Tuesdays 12:00 -2:00 pm 

How Long: June 4 through August 27

Where: TBA

OVERVIEW

The goal of this workshop series will be to reduce the amount of time required for an incoming MBTP graduate student to become fully independent in common structural and biophysical techniques. The workshop series will target students that have just completed their first year of rotations as well as more established young scientists seeking to augment their skill set. The 2019 workshop will train students to determine a straightforward crystal structure. Our workshop targets will be pre-selected with an eye to feasibility and publication.

The series will be led by a senior postdoctoral fellow, who will be selected via an internal competition. We anticipate that these workshop leaders will be applying for positions as independent faculty in the fall after the workshop. We require that the workshop leaders will correspond a manuscript describing their results within 1-year after accepting an independent position.

The impact of the workshop series is multi-fold. MBTP students will enter their selected laboratories with a stronger skill set, making them more productive during their thesis research. Moreover, students taking these workshops are likely to complete graduate school with up to two additional contributing author publications. The replacement of current programming with the workshop series will ensure that this training will occur without additional time away from the laboratory. Finally, the strategy of using senior postdocs as workshop leaders is expected to cross-pollinate laboratory expertise and foster new mentoring relationships between the workshop leaders and each student.

FACULTY

Our request:Please bring this to the attention to relevant senior postdocs and graduate students

What you get:Additional expertise for incoming students without using lab resources, your time, or additional time on the part of the trainees. Participating postdocs and students from your lab will be competitive for their next position.

POST-DOCS

Our request:We are seeking one or two senior postdocs to act as workshop leaders. The ideal candidate is planning on going on the job market next fall and anticipates that teaching will be one component of their next position.  Qualified postdocs will have expertise in crystallization and structure determination, and can trouble shoot experimental difficulties independently. You will run a weekly workshop that will take students through the attached syllabus (we have some targets lined up, but will also invite you to nominate targets that you propose to work on in your independent laboratory). You must agree to publish the results within 1 year of beginning your faculty position (as corresponding author). The time commitment is anticipated to be ~2 hrs per week for the workshop itself, including a short lecture that starts each session, plus 1-2 hors set up time.

What you get: Teaching experience on your cv, a group of graduate students collecting preliminary data on your proposed faculty projects, a corresponding author publication from your independent laboratory, and a $1000 stipend.

To apply: Send (1) a 1-page description that explains your rationale for wanting to lead a workshop, including your career goals and how this fits in; (2) a letter of reference from your mentor that must confirm that they support you in this activity; (3) a cv that includes all publications, but specifically highlights publications where you determined one or more structures. For these papers, please briefly describe (1-3 sentences) how the structure was determined and any challenges encountered. Applications should be sent to tina.iverson@vanderbilt.edu by 5 PM May 1.

SENIOR GRADUATE STUDENTS

Our request:We are seeking two to three senior graduate students to act as teaching assistants for the workshop. Qualified graduate students will be Y3-5, will have passed their qualifying examinations, and will have experience in crystallization and structure determination. You will assist the lead postdoc by helping to prepare materials and by demonstrating techniques.

What you get: Teaching experience on your cv, a co first-authorship when the manuscript is published, and a $750 stipend.

To apply: Send (1) a 1-page description that explains your rationale for wanting to be a teaching assistant, including your career goals and how this fits in; (2) a letter of reference from your mentor that must confirm that they support you in this activity; (3) a cv that includes all publications, but specifically highlights publications where you determined one or more structures. For these papers, please briefly describe (1-3 sentences) how the structure was determined and any challenges that were encountered. Applications should be sent to tina.iverson@vanderbilt.edu by 5 PM May 1.

WORKSHOP ATTENDEES

Our request:We are seeking up to 30 workshop attendees that want to learn to determine a straightforward crystal structure. Attendees may be at any level (postdocs, students, staff) and no experience is necessary. There will be a $100 fee for this workshop, payable by your PI. The fee may be waived by PI request.

What you get:You learn a new skill and will get a contributing authorship on the manuscript if you attend all sessions (attendees may miss one session for a conference).

To apply: Send (1) a 1/2-page description that explains your rationale for wanting to be attend the workshop; (2) a letter of from your mentor that confirms that they support you in this activity (this need not be a letter of reference, but simply something indicating that they are aware you plan to attend the workshop). Applications should be sent tina.iverson@vanderbilt.edu by 5 PM May 1.

WORKSHOP PUBLICATIONS

2017 Workshop
Starbird, CA#, Perry, N. A#, Chen, Q.#, Berndt, S.$, Yamakawa, I.$, Loukachevitch, L. V.$, Limbrick, E.M., Bachmann, B.O., Iverson, T.M., McCulloch, K M*. (2018) Structure of the bifunctional everninomicin biosynthetic enzyme EvdMO1 suggests independent activity of the fused methyltransferase-oxidase domains. Biochemistry, 57: 6827-6837. PMCID in process.

2018 Workshop (manuscript in preparation)
Bender BJ#, Stubbs HE$, Bryant JM$, Campos-Doerfler L$, Garcia V$, Ghodke PP$, Sebastian M$, Okwei E$, Reddish MJ$, Whitehead B$, Ynigez-Gutierrez A$, Iverson TM, Berndt S*, Sharma P* “Structure and binding properties of the Neu5Ac/Neu5Gc promiscuous adhesin from Streptococcus sanguinis strain SY10”

* indicates postdoctoral workshop leader and corresponding author
# indicates graduate student workshop TA and first (or co-first) author
$ indicates workshop participant

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