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Lori Jordan, M.D., Ph.D.

Associate Professor of Pediatrics, Neurology, and Radiology
Associate Director, Pediatric Neurology Residency Program


Our multidisciplinary research team studies cerebral hemodynamics, cerebral blood flow and oxygen extraction fraction, in adults and children with sickle cell disease (SCD) and other medical conditions that increase stroke risk, using novel MRI measures. We have developed applications for novel, hemodynamic imaging to assess key clinical questions regarding stroke risk and cerebrovascular reserve in SCD. We also use diffusion tensor imaging to assess how altered cerebral hemodynamics affect microstructural tissue integrity in the brain, and in turn how this impacts cognitive function and recovery after brain injury. We have expanded this work to assess brain microstructure and metabolic function using MRI methods in children with type 1 diabetes.