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Matthew Schrag M.D., Ph.D.

Assistant Professor of Neurology, Vanderbilt University School of Medicine

The SchragLAB is focused on discovering shared molecular pathways between Alzheimer’s disease and cerebral amyloid angiopathy. We have two major projects, one characterizing lysosome function in neurons in Alzheimer’s disease and the other characterizing molecular mechanisms of vascular degeneration and microvascular network disruption in cerebral amyloid angiopathy. We study human brain tissue, mouse model systems and cell culture models, including complex three-dimensional multi-cellular in vitro methods, and use advanced microscopic techniques including high-content imaging, atomic force microscopy and CLARITY-based three-dimensional microscopy.
Twitter @LABSchrag