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Vanderbilt Brain Institute

Paul Newhouse, M.D.

Jim Turner Chair in Cognitive Disorders
Professor of Psychiatry, Pharmacology, and Medicine
Director, Vanderbilt Center for Cognitive Medicine
Clinical Core Director, Vanderbilt Alzheimer’s Disease Research Center
Physician-Scientist, VA-TVHS GRECC

Dr. Newhouse is a physician scientist focusing on pathological brain aging, particularly Alzheimer’s disease, including identifying biological vulnerabilities leading to increased risk of the development of Alzheimer’s disease in women and individuals with Down syndrome.  A particular interest is the role of brain cholinergic systems in cognitive decline, utilizing advanced methods such as human positron emission tomography (PET), MRI imaging (functional and structural), and experimental neuropharmacology. The Newhouse laboratory also collaborates on development of novel therapeutics for Alzheimer’s disease from first in human studies to multicenter clinical trials.