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Rizwan Hamid, M.D./ Ph.D.

Professor of Pediatrics, Dorothy Overall Wells Chair in Pediatrics, Pediatric Medical Genetics

The research focus of this project is to: A) Understand and further define the cellular and molecular basis of TGIF’s role in normal and leukemic HSC function using mouse models, B) Gain a better understanding of TGIF transcriptional pathway by identify downstream TGIF targets in HSC and use genetic and genomics approaches to identify genes and genomic regions that regulate TGIF expression, C) Study the effects of single nucleotide polymorphisms (SNPs) on TGIF function and thus leukemic cell biology.