Sebastian Joyce, Ph.D.

Sebastian Joyce, Ph.D.

Professor of Pathology, Microbiology and Immunology

A-4223 Medical Center North
1161 21st Avenue South
Nashville, TN 37232-2363
(615) 322-1472


The focus of our research programme is on IMMUNOLOGIC RECOGNITION that controls T lymphocyte function in health and disease.  Sensing and actuating are fundamental to physiologic systems, which evolved to sense perturbations in milieu intérieur (homeostasis) and to actuate an appropriate response so as to restore a set homeostatic state unique to an organism. The initiation of an immune response begins with sensing of an antigenic substance—this sensing is called IMMUNOLOGIC RECOGNITION.

Lab URL:  https://www.vumc.org/joyce-lab