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Job Opportunity: Senior Scientist – Cell Therapy, AstraZeneca, Gaithersburg, MD

Posted by on Wednesday, February 23, 2022 in Job Opportunities .

Title: Senior Scientist – Cell Therapy

Location: Gaithersburg, MD

AstraZeneca’s Oncology R&D Drug Discovery group is building its Cell Therapy team in Gaithersburg, MD.  We are seeking Scientist who possess:

  • Strong scientific expertise in T cell biology, cellular therapy and extensive knowledge in the mechanisms that regulate CAR-T cell functions.
  • The skills to design and conduct laboratory projects/experiments, develop methods, generate, and interpret and report on scientific data.
  • A PhD in Immunology or related field with relevant experience in industry or academia and a significant publication record.


  • Conducts hands-on primary immune cell culturing, immune functional assays, and in vivo experiments.
  • Contributes to the experiments plans and designs, independent data analysis and interpretations.
  • Supports a team and works collaboratively with project managers to ensure the efficient relay of information and forward translation of data.
  • Maintains a well-developed understanding of approaches to drug discovery and applies a broader functional knowledge of the procedures used by diverse project groups to support the department where needed.
  • Assesses and reports data, with little or no guidance, in a clear and concise manner, with a clear understanding of its implications within the overall context of drug discovery.
  • Provides technical instruction to the team and allocates administrative work where possible
  • Shares relevant external published papers with peers.
  • Communicates and shares information between distinct projects within the bioscience function and across other functions.
  • Ensures own work, and work of peers, is compliant with Good Laboratory Practice, Safety, Health and Environment standards and all other relevant internal AstraZeneca standards and external regulations.


  • PhD in Immunology or equivalent and/or professional certifications in immunology or T cell biology.
  • 3+ years of experience in cell therapy
  • Proficiency in cell culture of established cell lines and primary immune cells.
  • Hands-on expertise in T-cell functional characterization assays as in vitro cytotoxicity, proliferation, cytokine measurement.
  • Well-developed understanding and expertise in molecular and cellular biology of immune cells, design and performing functional assays, cell transfection/ transduction.
  • Proficiency with multi-parameter flow cytometry (Immunostaining, acquisition, and analysis).

To apply:—Gaithersburg—MD/Senior-Scientist—Cell-Therapy_R-121810-2

Deadline: March 14, 2022

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