Job Opportunity - Senior Scientist - Molecular Diagnostics, Aegis Sciences Corporation (Nashville, TN)

Kim Petrie
February 11, 2015

The Senior Scientist – Molecular Diagnostics will lead a team in supporting ongoing development of our  molecular diagnostic products and clinical services. The ideal candidate will have a deep understanding of molecular biology and next generation sequencing, including data interpretation, and has a proven track record of building and supporting scalable, clinical-grade NGS and other molecular assays in a dynamic multidisciplinary environment. Responsibilities of this position include supporting the development and optimization of new and existing NGS-based and molecular clinical diagnostic tests. The high complexity nature of the work requires excellent attention to detail, excellent written and verbal communication skills, the ability to multi-task, manage schedules and work in a team environment.

Qualified candidates must possess:

  • A PhD in Molecular Biology, Microbiology, Biochemistry or Genetics required 
  • A minimum of 2 years’ experience working in industry and/or Academia required; 5 -10 years of relevant biosciences experience with DNA sequencing and Genotyping platforms preferred
  • Demonstrated ability to clearly communicate scientific results in internal and external presentations and publications
  • Proven ability to work independently and collaboratively in a dynamic, fast paced team environment; ability to independently manage multiple projects of varying degrees of complexity
  • Deep understanding and familiarity with molecular biology methodology used for clinical applications;  Competitive candidates should be comfortable interacting with clinical investigators
  • Demonstrated expertise in molecular biology and understanding of the principals and practices of the following skills/ techniques strongly preferred:
    • PCR, qPCR using TaqMan and SYBR green analysis, DNA Sequencing (NGS and Sanger) protocols and various target-enrichment approaches
    • Expertise in wide range of customized assay designs for pharmacogenetics, bacterial identification and resistance markers, specific cancer types and B-cell receptor rearrangements
    • Demonstrated use of lab automation for DNA/RNA extraction and liquid handler platforms
    • Expertise with design and development of CGH assays for analysis of cancer samples
    • Demonstrated practical use of various qPCR and DNA sequencing platforms, including operation, maintenance and calibration (e.g. ViiA7, QuantStudio, MiSeq, 3130xL, NextSeq,  etc)
    • Good understanding of NGS data management and   analysis (e.g. MiSeq Reporter, VariantStudio, NextGENe, Partek, IGV etc)
  • Able to prioritize and drive to results with a high emphasis on quality, including working with quality officers to ensure compliance with CLIA and other regulatory bodies

To apply, please visit the Aegis website.