Associate Principal Scientist: In Vivo Scientist Diabetic Nephropathy, Preclinical Research in Drug Discovery
CVMD Bioscience Department
AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialization of prescription medicines for some of the world’s most serious diseases. But we're more than one of the world's leading pharmaceutical companies. AstraZeneca strives to be a unique workplace culture that inspires innovation and collaboration where employees are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.
The successful candidate supports projects with scientific input in the in vivo model strategy and delivers key decision making data. A broad expertise in whole body physiology and animal models of kidney disease and diabetic nephropathy is a requirement of the scientist. The scientist is responsible to identify and validate novel methods and technologies to support new scientific concepts and projects in Diabetic Nephropathy. Will lead by example at the bench and encourage the development of less experienced scientists. The successful candidate will champion and develop new scientific ideas and projects. The successful candidate must be able to collaborate closely and effectively with other PhD scientists and technicians within the team as well as specialists, from a range of disciplines, within project groups .
- Performing, supervising, evaluating, presenting and reporting in vivo pharmacological studies for projects from pre-Target Identification to LCM phase
- Provides disciplinary scientific leadership and mentorship for less experienced scientists.
- Active contribution to the Diabetic Nephropathy strategy development including target identification
- Contribute proactively to a vibrant and innovative working environment where improvements and new ideas are adopted and freely shared.
- Documentation of the work according to AstraZeneca standards, and prepare the preclinical pharmacology part of regulatory documents as appropriate.
- Work collaboratively within Bioscience and the iMed to deliver on project key questions and to ensure flow-scheme connectivity and translatability between in vivo and in vitro models.
- Publish findings in peer-reviewed journals
- A PhD in renal biology or physiology, or a PhD in metabolism bioscience and post-doctoral experience in renal biology or diabetic nephropathy
- Scientific knowledge in the Diabetic Nephropathy field and a strong understanding of renal biology and assessment of renal function
- Strong publication record in the renal field
- Experience of and experimental skills in the development and use of animal models of kidney disease, preferably in Diabetic Nephropathy
- Experience in pharmaceutical R&D is an advantage
- Strong communication skills as well as high degree of flexibility and team working skills
For more information about the position please contact: Anette Ericsson, Department of Bioscience, Mölndal at Anette.E.Ericsson@astrazeneca.com. Email requests will be answered within 10 days.
Closing date for applications - September 15th, 2013.