Job Posting; Bioinformatics Scientist, Intermountain Cancer Genomics, Utah

Kate Stuart
September 9, 2014

About Us
What does it mean to be a part of Intermountain Healthcare? It means that the quest for clinical excellence is not just a goal, but a given. It means building an environment where physicians and employees can deliver the best in medicine. And it's realizing each employee or volunteer is vital to the healing process, because we can only achieve the extraordinary together. Being a part of Intermountain Healthcare means joining with a world-class team of over 32,000 employees and embarking on a career filled with opportunities, strength, innovation, and fulfillment. Our mission is: excellence in the provision of healthcare services to communities in the Intermountain region. Our patients deserve the best in medicine, and we deliver. Intermountain Cancer Genomics (ICG) uses genetic mapping to develop personalized treatment options for cancer patients. Headquartered in St. George, Utah, we are able to analyze a patient's tumor DNA and identify mutations to determine why and how the tumor is growing, and most importantly, what can be done to treat it.

We offer a comprehensive service including DNA testing, results interpretation and drug procurement services. Intermountain Cancer Genomics is comprised of a group of internationally renowned physicians and scientists with expertise in cancer genomics.

We are seeking a full-time Bioinformatics Scientist to join the team!
Incumbents in this role provide the highest level of expertise in their respective area of focus. They are responsible for understanding and developing new test methodologies and analyzing current practices to ensure the best clinical practice to the patient populations served, while maintaining appropriate cost controls. This position has four main focuses: 1. Data analysis and interpretation, relative to the hospital clinical practice, 2. Study design and data interpretation relative to the research done in the department, 3. Acting as a consultant to discipline-specific personnel, Intermountain physicians, the Utah Department of Health, and other Intermountain committees, and 4. Initiation of approved independent research projects.

Job Essentials:

  • Consults with ICG leadership in review of current processes and practices to analyze their effectiveness and efficiency in providing quality patient care.
  • Develops and designs relevant studies (protocol writing, grant writing, data analysis, and interpretation) to improve clinical care within department.
  • Delivers clinical and scientific presentations to clinicians, staff, and other applicable personnel to build awareness of issues related to the ICG's focus and to educate on recommendations for changes or updates in processes or procedures.
  • Acts as a mentor to junior staff members and students.
  • Presents information in a comprehensive and understandable manner at relevant local and global conferences and represents Intermountain Healthcare by upholding its Mission, Vision, and Values.
  • Ability to prepare sample sheets as well as perform data analysis on MiSeq generated raw files (example, convert fastq or BAM into vcf or other suitable formats).
  • Ability to demonstrate superior knowledge in data analysis with proficiency in R, Python, Perl, and/or C/C++/C#/java with troubleshooting expertise. He/she should demonstrate familiarity with Mac/Linux environments with developed analytical and problem-solving skills.
  • Experience/ability to align Illumina reads to human reference genome, analyze and distinguish CNVs, SVs, SNPs, INDELs and any other re-arrangements or expression variations with expert level familiarity with computational, statistical or mathematical methods.
  • Knowledge in assembling, phasing, annotating and characterizing targeted gene panel. Briefly, Annotate detected variations with various information (i.e., gene, mutation effect, disease association, etc). Display information in the genomic context, like UCSC Genome Browser.
  • Knowledge or experience using existing biostatistics and bioinformatics algorithms like- bwa, bowtie, cufflinks, etc., and if necessary write and validate custom data analysis scripts (preferred and a big plus).
  • Ability to prepare & deliver detailed written & verbal technical analyses report.
  • Ability to carry out genomics assays/experiments. Preferred experience with Illumina MiSeq platform and willing to learn new techniques.
  • Motivated to work on bench to prepare libraries for MiSeq analysis and also troubleshoot techniques and refine SOP.
  • Routinely perform maintenance for MiSeq and other required equipment.
  • Strong record-keeping and communications skills
  • Ability to multitask and meet deadlines in a fast-paced, result-oriented environment.
  • Publication(s) demonstrating required skill sets (example- MiSeq data analysis, CNV calling, SV identification, genome alignment and annotation).

Minimum Qualifications:

  • PhD in associated field of focus followed by postdoctoral training program related to field. Degree must be obtained through an accredited institution. Education is verified.
  • Eight years of advanced research experience.
  • Two years of lab experience (bench work and data analysis); research background in the fields of Oncology or Genetic Diseases preferred.
  • Comprehensive knowledge of department's applicable state and federal regulatory standards. Excellent communication and presentation skills.

Preferred Qualifications:

  • Lead author of articles published in nationally-recognized peer-review journals.
  • Mentoring and teaching experience.

To apply, please go to JOB ID: 157683

Please Note
All positions subject to close without notice. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.