Job Posting: Postdoc TGF-β, Leiden University Medical Center, Leiden, Netherlands

Rachel Howell
December 5, 2014

Postdoc TGF-β in cancer and cardiovascular biology m/f, Leiden

The position
Can you help us break the viscous circle causing vascular remodelling? Research by the Vascular Biology/Signal Transduction team of the Department of Molecular Cell Biology holds the hypothesis that an imbalance in TGF-β and BMP signalling and a vicious circle of alterations in pulmonary blood flow velocity and pressure are at the basis of vascular remodelling in PH. Our aim is to break the vicious circle through multidisciplinary research using patient and preclinical material. We are looking for two Postdocs to join our team and investigate the molecular basis of subverted TGF-β signal transductions in cardiovascular biology.  

Your profile
You are a highly motivated and experimentally talented scientist who:

  • Holds a recent PhD
  • Has a strong background in biochemistry and molecular cell biology
  • Has experience in signal transduction
  • Is driven to answer important fundamental and biomedical research questions
  • Has reported and published research accomplishments

What we offer
You will be employed on the basis of a 36-hour week. Appointment is for two years, possibly to be extended. Your salary will depend on your qualifications and experience, with a maximum of € 4,070 gross per month based on a full time position (scale 10 of the Collective Labour Agreement for University Hospitals).

The organisation 
The LUMC is a centre for medical innovation that aims to improve patient care through scientific research. It trains doctors, medical care specialists and researchers for this purpose.

The Vascular Biology/Signal Transduction team of the Department of Molecular Cell Biology is interested in unravelling mechanisms by which TGF-β family members elicit their multifunctional cellular effects and how perturbation in their signal transduction pathways contribute to diseases. Our long term aim is to translate our findings for the development of novel treatments.

Further information
A detailed description of this position can be found on (select ‘Job opportunities). If you have any questions or would like more information about this position, please contact Professor Peter ten Dijke, Department of Molecular Cell Biology, telephone +31 (0)71 526 9271, email

How to apply
If you are interested in this position, please send your application letter and CV with a description of research accomplishments and contact information for two references to Please clearly quote the job vacancy number D.14.VC.MP.18/19/SC48. You may also apply through the website ‘working for us’).