{"id":18265,"date":"2022-10-19T12:15:58","date_gmt":"2022-10-19T17:15:58","guid":{"rendered":"https:\/\/medschool.prd.vanderbilt.edu\/career-development\/?p=18265"},"modified":"2022-10-19T12:16:58","modified_gmt":"2022-10-19T17:16:58","slug":"senior-bioinformatics-scientist-genomics-database-management","status":"publish","type":"post","link":"https:\/\/medschool.vanderbilt.edu\/career-development\/2022\/10\/19\/senior-bioinformatics-scientist-genomics-database-management\/","title":{"rendered":"Senior Bioinformatics Scientist- Genomics Database Management"},"content":{"rendered":"<p>The Cruchaga lab (<a href=\"https:\/\/cruchagalab.wustl.edu\/\">cruchagalab.wustl.edu<\/a>) which is part of the NeuroGenomics and informatics (NGI) center at Washington University School of Medicine is looking for a Senior Bioinformatics Scientist with expertise in programming, database management, curation and phenotypic harmonization to join our team. The lab\u2019s goal is dedicated to advancing the understanding of neurodegenerative diseases such as Alzheimer disease, other dementias, and stroke, by generating, analyzing and leveraging multi-tissue multi-omic data from large and well-characterized cohorts. We are seeking applicants for this senior position to lead the management of longitudinal and cross-sectional phenotypic data.<\/p>\n<p>Primary Duties and Responsibilities<br \/>\nLead various aspects of computer programing, database management and optimization. Should have expertise in data stewardship, transformation, quality control and consolidation. Familiar managing large phenotypic and clinical data sets to generate error-free reports available for researchers.<br \/>\nConceptualize, design, develop and optimize algorithms and computer programs to support databases, data management and associated applications.<br \/>\nCurate and maintain phenotypic databases, updating and validating longitudinal and cross-sectional data.<br \/>\nHarmonize phenotypic data; provide a centralized, confidential, and secure access to phenotypic data for the cores, projects, researchers and collaborators.<br \/>\nProvide expertise for data management and analysis solutions to store and extract biological information from large data sets and associated applications.<br \/>\nProcesses, transform and apply qualify control steps for large data sets and associated platforms.<br \/>\nServe as the lead person for data input, data extraction and for the generation of tables and reports.<br \/>\nMain point of contact to assists Principal Investigator in data request management.<br \/>\nSolves practical problems relating to data harmonization and curation of large datasets.<br \/>\nProvides technical support and assistance with data collection and report generation.<br \/>\nTrains other researchers and staff on everyday use of databases.<br \/>\nEvaluates commercial and academic bioinformatics software.<br \/>\nAssists with grant preparation, clarification of methods, data generation and results description.<br \/>\nResponds to data queries and assist junior staff on phenotypic data.<\/p>\n<p>Preferred Qualifications<br \/>\nMaster or PhD degree in bioinformatics, epidemiology, computer sciences, statistics, genetics or related. Master with at least 10 years or PhD with at least five years of experience in data management, statistical analysis and data quality control for a genomics or biological cores. Expert knowledge in building and optimizing databases for clinical sciences or biological cores.<br \/>\nAction-oriented, resourceful, and creative individual to lead a vertical program.<br \/>\nExcellent understanding of genetics, clinical data, probabilistic models, statistics, machine learning, and discrete mathematics.<br \/>\nExpertise in diverse bioinformatics tools for data storage and biological core management.<br \/>\nPrevious experience working for a genomics cores with biological and clinical data.<br \/>\nProficiency in scientific programming languages (e.g., Python, R, Perl, Java), in a UNIX\/Linux and Windows environment.<br \/>\nExperience working with structured data in SQL and NoSQL Databases.<br \/>\nSolid programming experience required.<br \/>\nAbility to work in a team environment to utilize technical skills to foster a collaborative environment in the phenotypic team.<br \/>\nAbility to prioritize work effectively to meet rapid evolving timelines.<br \/>\nMust be flexible, with ability to respond to changing priorities rapid and effectively<br \/>\nExpert coding level in FileMaker Pro required<br \/>\nExperience in clinical and medical research data management and analysis, beneficial.<\/p>\n<p>Deadline: January 18, 2023<\/p>\n<p>For more information and to apply, please send a CV and cover letter to Dr. Carlos Cruchaga at <a href=\"mailto:cgleason@wustl.edu\">cgleason@wustl.edu<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Cruchaga lab (cruchagalab.wustl.edu) which is part of the NeuroGenomics and informatics (NGI) center at Washington University School of Medicine is looking for a Senior Bioinformatics Scientist with expertise in programming, database management, curation and phenotypic harmonization to join our team. The lab\u2019s goal is dedicated to advancing the understanding of neurodegenerative diseases such as&#8230;<\/p>\n","protected":false},"author":298,"featured_media":11694,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[100],"tags":[7],"class_list":["post-18265","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-job-opportunities","tag-job-opportunities"],"acf":[],"jetpack_featured_media_url":"https:\/\/cdn.vanderbilt.edu\/t2-main\/medschool-prd\/wp-content\/uploads\/sites\/5\/2020\/01\/JOB.jpg","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/medschool.vanderbilt.edu\/career-development\/wp-json\/wp\/v2\/posts\/18265","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medschool.vanderbilt.edu\/career-development\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medschool.vanderbilt.edu\/career-development\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medschool.vanderbilt.edu\/career-development\/wp-json\/wp\/v2\/users\/298"}],"replies":[{"embeddable":true,"href":"https:\/\/medschool.vanderbilt.edu\/career-development\/wp-json\/wp\/v2\/comments?post=18265"}],"version-history":[{"count":2,"href":"https:\/\/medschool.vanderbilt.edu\/career-development\/wp-json\/wp\/v2\/posts\/18265\/revisions"}],"predecessor-version":[{"id":18270,"href":"https:\/\/medschool.vanderbilt.edu\/career-development\/wp-json\/wp\/v2\/posts\/18265\/revisions\/18270"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medschool.vanderbilt.edu\/career-development\/wp-json\/wp\/v2\/media\/11694"}],"wp:attachment":[{"href":"https:\/\/medschool.vanderbilt.edu\/career-development\/wp-json\/wp\/v2\/media?parent=18265"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medschool.vanderbilt.edu\/career-development\/wp-json\/wp\/v2\/categories?post=18265"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medschool.vanderbilt.edu\/career-development\/wp-json\/wp\/v2\/tags?post=18265"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}