2014-2015 Journal Club
Date | Speaker | Topic |
09/02/2014 | Tom Stricker | Putative cis-regulatory drivers in colorectal cancer |
09/09/2014 | Dave Cortez | ATR Mediates a Checkpoint at the Nuclear Envelope in Response to Mechanical Stress |
09/16/2014 | Seth Bordenstein | Sympatric Speciation in a Bacterial Endosymbiont Results in Two Genomes with the Functionality of One |
09/23/2014 | Bill Tansey | Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis |
09/30/2014 | Kathy Gould | Cytokinesis failure triggers Hippo tumor suppressor pathway activation |
10/07/2014 | Maria Hadjifangiskou | Self-regulation of exopolysaccharide production in Bacillus subtilis by a tyrosine kinase |
10/14/2014 | Donna Webb | An extracellular-matrix-specific GEF-GAP interaction regulates Rho GTPase crosstalk for 3D collagen migration |
10/21/2014 | Julie Sterling | Real-time intravital imaging establishes tumor-associated macrophages as the extraskeletal target of bisphosphonate action in cancer |
10/28/2014 | Eric Skaar | Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile |
11/04/2014 | Peggy Kendall | Dynamic signaling by T follicular helper cells during germinal center B cell selection |
11/11/2014 | Gregor Neuert | Validation of noise models for single-cell transcriptomics |
11/18/2014 | Kathy Friedman | Rif1 controls DNA replication by directing Protein Phosphatase 1 to reverse Cdc7-mediated phosphorylation of the MCM complex |
12/02/2014 | Neil Osheroff | A DNA-Dependent Protease Involved in DNA-Protein Crosslink Repair |
12/09/2014 | Dan Moore | Regulatory B cells are induced by gut microbiota-driven interleukin-1β and interleukin-6 production. |
01/06/2015 | Michelle Southard-Smith | Heterogeneity and phenotypic plasticity of glial cells in the mammalian enteric nervous system |
01/13/2015 | Tim Cover | Native structure of a type IV secretion system core complex essential for Legionella pathogenesis |
01/20/2015 | David Miller |
Regulation of Axon Guidance by Compartmentalized Nonsense-Mediated mRNA Decay |
01/27/2015 | Andrea Page-McCaw | Subcellular Trafficking of FGF Controls Tracheal Invasion of Drosophila Flight Muscle |
02/03/2015 | Jialiang Wang | Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex |
02/10/2015 | Jonathan Irish | High-dimensional analysis of the murine myeloid cell system |
02/17/2015 | Jim Goldenring | A dynamin 1-, dynamin 3- and clathrinindependent pathway of synaptic vesicle recycling mediated by bulk endocytosis |
02/24/2015 | Alyssa Hasty | Metabolic Dysfunction Drives a Mechanistically Distinct Proinflammatory Phenotype in Adipose Tissue Macrophages |
03/3/2015 | Rebecca Cook | mTOR overcomes oncogene-induced senescence in BRAF-mutant melanomas |
03/10/2015 | Tony Weil | The dyskerin ribonucleoprotein complex as an OCT4/SOX2 coactivator in embryonic stem cells |
03/17/2015 | Jason MacGurn | A feedforward mechanism for regulation of PARKIN by PINK1 kinase |
03/24/2015 | Sandy Zinkel | Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation |
03/31/2015 | Rebecca Ihrie |
Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion |
04/07/2015 | Ken Lau | Single-Cell Analysis of Proxy Reporter Allele-Marked Epithelial Cells Establishes Intestinal Stem Cell Hierarchy |
04/14/2015 | Todd Graham | Intracellular Cholesterol Transport at Membrane Contact Sites |
04/21/2015 | Ron Emeson | Hypothalamic POMC neurons promote cannabinoid-induced feeding |
04/28/2015 | Jennifer Pietenpol | Ferroptosis as a p53-mediated activity during tumour suppression |
05/05/2015 | Chris Aiken | Horizontal Transmission of Clonal Cancer Cells Causes Leukemia in Soft-Shell Clams |
05/12/2015 | Matt Tyska | Ena/VASP Enabled is a highly processive actin polymerase tailored to self-assemble parallel-bundled F-actin networks with Fascin |