Transforming growth factor, gastrointestinal carcinogenesis, ras oncogene, cancer, cell cycle, malignancy, post-transcriptional modification, proteomics, signal, transduction, transformation, translation
R. Daniel Beauchamp, MD, is the John Clinton Foshee Distinguished Professor of Surgery, Chairman of the Section of Surgical Sciences, and Surgeon-in-Chief of Vanderbilt University Hospital and has held these positions since July 2001 and on the faculty at Vanderbilt since December 1994. He holds joint appointments as professor in the departments of Cell and Developmental Biology and Cancer Biology. He also serves as Deputy Director of the Vanderbilt-Ingram Cancer Center. Dr. Beauchamp has two active R01 grants from NIH, and leads one of the main projects in the GI Cancer SPORE. Dr. Beauchamp's primary area of research interest has been in colorectal carcinogenesis, the biology of cancer cell invasion and metastasis, and in the identification of novel molecular biomarkers and therapeutic targets in colorectal and other alimentary tract malignancies. His work applies DNA microarray and proteomic technology to identify novel biomarkers and therapeutic targets in human colorectal cancer samples. He also uses molecular genetics, chemical biology and cell biological approaches to examine mechanistic questions in cancer biology in both cell culture and mouse models. In addition to the basic cancer research Dr. Beauchamp works in collaboration with his Medical Oncology and Radiation Oncology colleagues to accrue cancer patients to approved clinical trials. He has trained and mentored numerous junior faculty members, physician scientist fellows, medical students, graduate students and post-doctoral fellows in his laboratory. He is one of the few surgeon members of the ASCI.
Dr. Beauchamp's clinical practice is primarily in General Surgical Oncology. He participates in the multidisciplinary gastrointestinal oncology clinic. Dr. Beauchamp's practice includes patients ith tumors of the esophagus, stomach, pancreas, colon and rectum. His group is actively pursuing improvement in outcomes for these tumors through application of multimodality therapy. In addition, Dr. Beauchamp has a large breast cancer and melanomapractice. He and his partners are skilled in the use of Sentinel lymph node mapping techniques and, stereotactic breast biopsy and participate in a multidisciplinary team along with Radiologists, Medical Oncologists, Pathologists, Radiation Oncologists and the Genetic counseling service to provide the most current and comprehensive diagnostic and therapeutic care available.