Role of integrins and extracellular matrix in epithelial biology
M.D., University of Witwatersrand, South Africa
M.MED., University of Cape Town, South Africa
Ph.D., University of Toronto, Canada
Postdoc., The Scripps Research Institute, CA, USA
Research Scientist, University of California, San Diego
The laboratory works on the basic role of integrins in epithelial cell biology. We utilize the kidney as a model system and perform biochemical techniques, cell biology and transgenic mice to understand the basic mechanisms whereby integrin-ECM interactions modify cell function. In addition, in collaboration with Dr. Charles Sanders, we perform structural functions on integrins utilizing NMR.