Roy Zent, Ph.D.

Roy Zent, Ph.D.

Professor of Medicine, Division of Nephrology & Hypertension

Thomas F. Frist, Sr. Chair in Medicine

Professor of Cell and Developmental Biology

Professor of Cancer Biology

C-3210 Medical Center North
(615) 322-4632


Role of integrins and extracellular matrix in epithelial biology

M.D., University of Witwatersrand, South Africa
M.MED., University of Cape Town, South Africa
Ph.D., University of Toronto, Canada
Postdoc., The Scripps Research Institute, CA, USA
Research Scientist, University of California, San Diego

Research Description

The laboratory works on the basic role of integrins in epithelial cell biology. We utilize the kidney as a model system and perform biochemical techniques, cell biology and transgenic mice to understand the basic mechanisms whereby integrin-ECM interactions modify cell function. In addition, in collaboration with Dr. Charles Sanders, we perform structural functions on integrins utilizing NMR.

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