Timothy Scott Blackwell, M.D.

Timothy Scott Blackwell, M.D.

Professor of Medicine, Division of Allergy, Pulmonary & CCM

Ralph and Lulu Owen Chair in Medicine

Professor of Cell and Developmental Biology

Professor of Cancer Biology

AAAS Fellow - 2018

T-1217 Medical Center North
(615) 343-4761

Transcriptional regulation and mechanisms of lung inflammation, injury, and fibrosis.

Research Description

My laboratory investigates lung inflamamtion/injury, remodeling, fibrosis, and development of lung cancer. Lung inflammation is important for host defense functions but can contribute to tissue injury when the inflammation is excessive or dysregulated. By studying the NF-kB transcription pathway, we hope to better understand factors that control lung inflammation, injury, and host defense. We are also interested in the basic mechanisms that lead to normal lung repair or fibrosis following injury and mechanisms by which chronic inflammation alters the lung microenvironment in a pro-tumorigenic manner.

Clinical Interest

acute lung injury/ARDS
idiopathic pulmonary fibrosis
lung cancer