- Norris SR, Ohi R. Cell Division: Centrosomes Have Separation Anxiety. Current biology : CB. 2017 Jun 19;27(12). R601-R603. PMID: 28633031 [PubMed].
Prior to mitosis, duplicated centrosomes are tethered together, which is thought to prevent mitotic defects. A new study establishes the role of tetrameric Kif25, a microtubule minus-end-directed kinesin-14 motor, in preventing premature centrosome separation through a microtubule-dependent pathway.