Chemical & Physical Biology Program

 

November 2017


If you have difficulty seeing this newsletter in your email reader, you can view it online.

 

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If you have any news or information to share with the CPB community, please let us know.

Chemical & Physical Biology Program

 

October 2017


If you have difficulty seeing this newsletter in your email reader, you can view it online.

 

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If you have any news or information to share with the CPB community, please let us know.

Chemical & Physical Biology Program

 

September 2017


If you have difficulty seeing this newsletter in your email reader, you can view it online.

 

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If you have any news or information to share with the CPB community, please let us know.

Chemical & Physical Biology Program

 

August 2017


If you have difficulty seeing this newsletter in your email reader, you can view it online.

Contents for this Issue

We welcome your comments on this newsletter and would like to hear about all of your good news and progress; please contact Michaela Fooksa or Christian Meyer with details.  You can also learn about the dates of all upcoming events on the CPB website, the GSA's Google Calendar, and the GSA's Facebook page (where, after liking the page, you can also share your memories and thoughts). 


CPB Retreat

I’d like to extend my hearty thanks and congratulations to Kevin Jagessar, Corey Hayford, and Chuck Herring for a job very well done at this year's CPB Program Retreat. Along with our Program Manager, Patty Mueller, and the other CPB Graduate Student Association officers, they worked diligently throughout the year to identify an excellent keynote speaker and organize all of the details – big and small – for the retreat. It is always a pleasure to work with such dedicated and talented people, and I hope they know how much I, the other faculty and students in the program, and our guests appreciate their outstanding work.

Bruce

 

Take a look at the pictures from the retreat here!


Message From Bruce

Each year at this time, we have the chance to welcome new students to our program and support them in their development as scientists.  This year, we are pleased that seven new students will be joining the CPB. They are:

 

In the Structural Biology and Molecular Biophysics track:

  •          Benjamin Brown (Jens Meiler, mentor)
  •          Shannon Smith (Jens Meiler and Charles Manning, mentors)
  •          Nicole Rodgers (Marija Zanic, mentor)

In the Systems Biology track:

  •          Geena Ildefonso (Carlos Lopez, mentor)
  •          Sarah Maddox (Vito Quaranta, mentor)

In the Chemical Biology track:

  •          Alexandria Oviatt (Neil Osheroff, mentor)

In the Imaging Science track:

  •          Spencer Waddle (Manus Donahue, mentor)

 

As you’ll note below, the program is sponsor a social hour on August 25.  We hope to see faculty as well as current and new students there!

 

Bruce Damon


Publications

Cao Z, Hutchison JM, Sanders CR, Bowie JU. Backbone Hydrogen Bond Strengths Can Vary Widely in Transmembrane Helices. Journal of the American Chemical Society. 2017 Jul 25

O'Brien E, Holt ME, Thompson MK, Salay LE, Ehlinger AC, Chazin WJ, Barton JK.Response to Comments on "The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport". Science (New York, N.Y.). 2017 Jul 21;357(6348)

Harris LA, Nobile MS, Pino JC, Lubbock ALR, Besozzi D, Mauri G, Cazzaniga P, Lopez CF. GPU-powered model analysis with PySB/cupSODA. Bioinformatics (Oxford, England). 2017 Jun 28.

Surdel MC, Horvath DJ, Lojek LJ, Fullen AR, Simpson J, Dutter BF, Salleng KJ, Ford JB, Jenkins JL, Nagarajan R, Teixeira PL, Albertolle M, Georgiev IS, Jansen ED, Sulikowski GA, Lacy DB, Dailey HA, Skaar EP. Antibacterial photosensitization through activation of coproporphyrinogen oxidase. Proceedings of the National Academy of Sciences of the United States of America. 2017 Jul 24.

Ostenson J, Robison RK, Zwart NR, Welch BE. Multi-frequency interpolation in spiral magnetic resonance fingerprinting for correction of off-resonance blurring. Magnetic resonance imaging. 2017 Jul 8

Claassen DO, Stark AJ, Spears CA, Petersen KJ, Van Wouwe NC, Kessler RM, Zald DH, Donahue MJ. Mesocorticolimbic hemodynamic response in Parkinson's disease patients with compulsive behaviors. Movement disorders : official journal of the Movement Disorder Society. 2017 Jun 19


Upcoming Events

CPB recruitment day

The new students will be starting soon! The poster session for the CPB recruitment day will be on August 25th from 12:00-3:00 in the atrium of Light Hall.  Happy hour at Cabana will follow at 5PM.  Please plan on setting up a lab poster and sticking around to talk to the new students!  For additional details please email Patty Mueller.

GSA Annual Elections

Monday August 14th, 411 A/B Lh

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PhD Career Connections: Nonprofit Leadership and Program Management

Wednesday, August 9th, 2017

11:00 AM to 12:00 PM

Light Hall 214

 

REGISTRATION REQUESTED

 

Maryrose Franko is the Executive Director of the Health Research Alliance (HRA) a multi-national consortium of nonprofit organizations working to maximize the impact of investment in biomedical research to improve human health.

Dr. Franko’s background includes over 20 years of program management at the Howard Hughes Medical Institute (HHMI), including strategic planning as well as creating, implementing, and managing over a dozen programs and initiatives. These include scientific research fellowships, an innovative university science education program, a joint initiative with the National Institutes of Health, and a student program at HHMI’s state-of-the-art research facility, Janelia Research Campus.

Dr. Franko received her PhD in molecular genetics from University of Southern California and did a post-doctoral fellowship at the National Institutes of Health before joining HHMI. Her collaboration to produce Making the Right Moves: A Practical Guide to Scientific Management for Postdocs and New Faculty, which was a joint effort of HHMI and Burroughs Wellcome Fund, contributed to the collaborative efforts that led to the creation of HRA. Franko was a founding board member of HRA, serving from 1995 to 2012. She has served as the Executive Director of the Health Research Alliance since 2015.

 

For questions, contact:

Angela Zito
Program Manager
Office of Career Development
Biomedical Research Education and Training
Vanderbilt University School of Medicine
340 Light Hall, Nashville, TN 37232-0301
https://medschool.vanderbilt.edu/career-development/
Follow our job feed on Twitter! https://twitter.com/VUBRETPhDJobs 
angela.zito@vanderbilt.edu
(615) 343-0775 (internal: 3-0775)


If you have any news or information to share with the CPB community, please let us know.

Chemical & Physical Biology Program

 

June 2017


If you have difficulty seeing this newsletter in your email reader, you can view it online.

Contents for this Issue

We welcome your comments on this newsletter and would like to hear about all of your good news and progress; please contact Michaela Fooksa or Christian Meyer with details.  You can also learn about the dates of all upcoming events on the CPB website, the GSA's Google Calendar, and the GSA's Facebook page (where, after liking the page, you can also share your memories and thoughts). 


CPB Retreat

I’d like to extend my hearty thanks and congratulations to Kevin Jagessar, Corey Hayford, and Chuck Herring for a job very well done at this year's CPB Program Retreat. Along with our Program Manager, Patty Mueller, and the other CPB Graduate Student Association officers, they worked diligently throughout the year to identify an excellent keynote speaker and organize all of the details – big and small – for the retreat. It is always a pleasure to work with such dedicated and talented people, and I hope they know how much I, the other faculty and students in the program, and our guests appreciate their outstanding work.

Bruce

 

Take a look at the pictures from the retreat here!


Welcome New CPB Students

We'd like to extend a warm welcome to the students who recently joined labs in the CPBP.

Ben Brown - Jens Meiler

Alexandria Oviatt - Neil Osheroff

Nichole Rodgers - Marija Zanic

Shannon Smith - Meiler/Manning

Spencer Waddle - Manus Donahue

Sarah Maddox - Vito Quaranta

Geena Ildefonso - Carlos Lopez


Upcoming Defense

Joe Alvin will be defending his PhD dissertation on June 22nd at 10 am in PRB 206.

As a reminder, students who attend will be entered into a raffle for a gift card!


If you have any news or information to share with the CPB community, please let us know.

Chemical & Physical Biology Program

 

May 2017


If you have difficulty seeing this newsletter in your email reader, you can view it online.

Contents for this Issue

We welcome your comments on this newsletter and would like to hear about all of your good news and progress; please contact Michaela Fooksa or Christian Meyer with details.  You can also learn about the dates of all upcoming events on the CPB website, the GSA's Google Calendar, and the GSA's Facebook page (where, after liking the page, you can also share your memories and thoughts). 


Retreat Update

Clear your calendars! Wednesday, May 24th will be our the CPB annual retreat. The speaker for the annual CPB retreat will be Dr. Benjamin Cravatt of the Scripps Institute. Dr. Cravatt's laboratory specializes in global analysis of enzyme function with the stated purpose of identifying therapeutic targets in human disease. The Cravatt Lab has been on the cutting edge of both technology development and basic science discovery of the enzymatic regulation of chemical signaling.

If you passed your qualifying exam in the past academic year you will be expected to give a talk. All other students are expected to have a poster to present. Solicitations for abstracts will be initiated soon.

Finally, we have been keeping attendance of the Lunch and Learn Seminars and will be drawing for a gift card based on attendance.


BRET Reunion

On June 1-2, 2017 the BRET office is having its inaugural reunion event marking the 25th anniversary of the IGP program. The CPBP will have a reception for current students and alumni on June 2 from 3:00 - 4:00 pm in the 6th floor Light Hall commons area.


Summer Travel Prep

Vanderbilt University must enforce public health mandates as required by public health authorities, and may also follow Medical Center and Student Health Center recommendations when the University determines them to be in the best interest of the Vanderbilt community and the public. Based on the aforementioned mandates and/or recommendations, the University may issue directives to students regarding isolation and/or quarantine. As a result, among other needed interventions, students in campus housing or students traveling abroad as part of Vanderbilt programs or activities may be required to relocate so that appropriate isolation and/or quarantine can be accomplished. Failure to comply with University directives may result in corrective action through the University’s accountability process.


Student Publications

Perreault AA, Benton ML, Koury MJ, Brandt SJ, Venters BJ. Epo Reprograms the Epigenome of Erythroid Cells. Experimental Hematology. 2017 Apr 11.

Chaplin, V, Caskey CF. Multi-Focal HIFU Reduces Cavitation in Mild Hyperthermia. J Ther Ultrasound. 2017 Apr 13;5:12.


If you have any news or information to share with the CPB community, please let us know.

Chemical & Physical Biology Program

 

April 2017


If you have difficulty seeing this newsletter in your email reader, you can view it online.

Contents for this Issue

We welcome your comments on this newsletter and would like to hear about all of your good news and progress; please contact Michaela Fooksa or Christian Meyer with details.  You can also learn about the dates of all upcoming events on the CPB website, the GSA's Google Calendar, and the GSA's Facebook page (where, after liking the page, you can also share your memories and thoughts). 


Message From the President

Dear CPB community,

Welcome to spring. Along with the cherry blossoms and longer days, spring marks the time of the year when the second years begin to gear up for qualifying exam season. The GSA holds a panel at the end of the semester to discuss format and tips with the second years, but owing to the diversity of the program, we do not organize mock qualifying exams. However, we encourage everyone to participate if asked as part of the "pay it forward" character we hope to foster within the CPB. If you are a student up coming on your exam and would like to know which upperclassmen are in your track, please reach out to me (christian.t.meyer@vanderbilt.edu) and I will connect you with a list.

Also, I would encourage everyone to attend our Lunch and Learn Seminar this month as our own Abigail Searfoss will be discussing the particularly pertinent topic of gender equality in the STEM disciplines. It is a topic usually obfuscated by mass media and politics, so I hope you will join us for a critical look at where we've been, where we are and where we are going. The first step in overcoming our demons is to acknowledge them.

Looking forward to seeing you there,

Christian Meyer


Lunch and Learn

The April Lunch and Learn will be held Monday, April 10 at 12:00 pm in LH 411 A/B. Our very own  Abigail Searfoss, president of VU-WiSE, will be discussing the progress and prospects of women in the STEM fields.

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Opportunities and Events

Women in the Academy is hosting a panel to discuss "Creativity in the Shadows: Working Beyond the Tenure Track" on Wednesday, April 5 at 12:00 in Buttrick 123.

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NSF Fellowship

Brennica Marlow received the prestigious NSF Graduate Research Fellowship for her research on Cholesterol Membrane Protein Interactions. Congratulations, Nica!


Retreat Update

Clear your calendars! Wednesday, May 24th will be our the CPB annual retreat. The speaker for the annual CPB retreat will be Dr. Benjamin Cravatt of the Scripps Institute. Dr. Cravatt's laboratory specializes in global analysis of enzyme function with the stated purpose of identifying therapeutic targets in human disease. The Cravatt Lab has been on the cutting edge of both technology development and basic science discovery of the enzymatic regulation of chemical signaling.

If you passed your qualifying exam in the past academic year you will be expected to give a talk. All other students are expected to have a poster to present. Solicitations for abstracts will be initiated soon.

Finally, we have been keeping attendance of the Lunch and Learn Seminars and will be drawing for a gift card based on attendance.


 

If you have any news or information to share with the CPB community, please let us know.

Chemical & Physical Biology Program

 

March 2017


If you have difficulty seeing this newsletter in your email reader, you can view it online.

Contents for this Issue

We welcome your comments on this newsletter and would like to hear about all of your good news and progress; please contact Michaela Fooksa or Christian Meyer with details.  You can also learn about the dates of all upcoming events on the CPB website, the GSA's Google Calendar, and the GSA's Facebook page (where, after liking the page, you can also share your memories and thoughts). 


Lunch and Learn

The February Lunch and Learn will be held Monday, March 13 at 12:00 pm in LH 411 A/B. The CPBP will be hosting our own version of a three minute thesis.

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Happy Hour

The next CPB Happy Hour will be Thursday, March 23 from 5-7 pm. The happy hour will take place at Mellow Mushroom on 21st Ave. Join us for food and drinks!


Opportunities and Events

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Are you a graduate student in the CPB program? Do you shop on Amazon? If you answered yes to those questions, you're in luck! New in 2017, CPB will be doing a raffle biannually for an Amazon gift card. All you have to do in attend the Lunch & Learn series and scheduled dissertations! Keep an eye out for a card swiper or sign in sheet at future events.


Recent Publications

Hardeman KN, Peng C, Paudel BB, Meyer CT, Luong T, Tyson DR, Young JD, Quaranta V, Fessel JP. Dependence on Glycolysis Sensitizes BRAF-Mutated Melanomas for Increased Response to Targeted BRAF Inhibition. Scientific Reports. 2017 Feb 16;7. 42604 p.

O'Brien E, Holt ME, Thompson MK, Salay LE, Ehlinger AC, Chazin WJ, Barton JK. The [4Fe4S] Cluster of Human DNA Primase Functions as a Redox Switch Using DNA Charge Transport. Science. 2017 Feb 24;355(6327).

Norris JL, Farrow MA, Gutierrez DB, Palmer LD, Muszynski N, Sherrod SD, Pino JC, Allen JL, Spraggins JM, Lubbock AL, Jordan A, Burns W, Poland JC, Romer C, Manier ML, Nei YW, Prentice BM, Rose KL, Hill S, Van de Plas R, Tsui T, Braman NM, Keller MR, Rutherford SA, Lobdell N, Lopez CF, Lacy DB, McLean JA, Wikswo JP, Skaar EP, Caprioli RM. Integrated, High-Throughput, Mulitomics Platform Enables Data-Driven Construction of Cellular Responses and Reveals Global Drug Mechanisms of Action. Journal of Proteome Research. 2017 Mar 13;16(3). 1364 - 1375.


 

If you have any news or information to share with the CPB community, please let us know.

Chemical & Physical Biology Program

 

February 2017


If you have difficulty seeing this newsletter in your email reader, you can view it online.

Contents for this Issue

We welcome your comments on this newsletter and would like to hear about all of your good news and progress; please contact Michaela Fooksa or Christian Meyer with details.  You can also learn about the dates of all upcoming events on the CPB website, the GSA's Google Calendar, and the GSA's Facebook page (where, after liking the page, you can also share your memories and thoughts). 


Lunch and Learn

The February Lunch and Learn will be held Monday, February 13 at 12:00 pm in LH 411 A/B. Philip Walker will discuss the Effective Use of the Biomedical Library in Research.

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Leaders in CPB Seminar

2nd Annual Leaders in Chemical and Physical Biology Seminar

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The 2017 Chemical and Physical Biology Seminar will be held on Tuesday, February 21st from 3:00-4:00 pm in 214 Light Hall. John Gore, Hertha Ramsey Cress Professor of Medicine, Professor of Biomedical Engineering, Molecular Physiology and Biophysics, and Physics and Astronomy, and Director of the Vanderbilt Institute of Imaging Science, will speak on the subject of "New Advances in Structural and Functional Neuroimaging." A festive reception will follow in the North Lobby of Light Hall. All CPB students should plan to attend.


Retreat Update

The speaker for the annual CPB retreat will be Dr. Benjamin Cravatt of the Scripps Institute.  Dr. Cravatt's laboratory specializes in global analysis of enzyme function with the stated purpose of identifying therapeutic targets in human disease.  The Cravatt Lab has been on the cutting edge of both technology development and basic science discovery of the enzymatic regulation of chemical signaling.  Please reserve Wednesday, May 24th, on your calendars for this event. Location TBA.


Opportunities and Events

Are you a graduate student in the CPB program? Do you shop on Amazon? If you answered yes to those questions, you're in luck! New in 2017, CPB will be doing a raffle biannually for an Amazon gift card. All you have to do in attend the Lunch & Learn series and scheduled dissertations! Keep an eye out for a card swiper or sign in sheet at future events.


Recent Publications

Chifman J, Arat S, Deng Z, Lemler E, Pino JC, Harris LA, Kochen MA, Lopez CF, Akman SA, Torti FM, Torti SV, Laubenbacher R. Activated Oncogenic Pathway Modifies Iron Network in Breast Epithelial Cells: A Dynamic Modeling Perspective. PLoS Computational Biology. 2017 Feb;13(2). e1005352


 

If you have any news or information to share with the CPB community, please let us know.

Chemical & Physical Biology Program

 

January 2017


If you have difficulty seeing this newsletter in your email reader, you can view it online.

Contents for this Issue

We welcome your comments on this newsletter and would like to hear about all of your good news and progress; please contact Michaela Fooksa or Christian Meyer with details.  You can also learn about the dates of all upcoming events on the CPB website, the GSA's Google Calendar, and the GSA's Facebook page (where, after liking the page, you can also share your memories and thoughts). 

This month, we would like to congratulate Mr. and Mrs. Christian Meyer on the birth of their son, Elijah,  born on January 5th!


Leaders in CPB Seminar

2nd Annual Leaders in Chemical and Physical Biology Seminar

I'm pleased to announce that the 2017 Chemical and Physical Biology Seminar will be held on Tuesday, February 21st from 3:00-4:00 pm in 214 Light Hall. John Gore, Hertha Ramsey Cress Professor of Medicine, Professor of Biomedical Engineering, Molecular Physiology and Biophysics, and Physics and Astronomy, and Director of the Vanderbilt Institute of Imaging Science, will speak on the subject of "New Advances in Structural and Functional Neuroimaging." A festive reception will follow in the North Lobby of Light Hall. All CPB students should plan to attend.


Retreat Update

The speaker for the annual CPB retreat will be Dr. Benjamin Cravatt of the Scripps Institute.  Dr. Cravatt's laboratory specializes in global analysis of enzyme function with the stated purpose of identifying therapeutic targets in human disease.  The Cravatt Lab has been on the cutting edge of both technology development and basic science discovery of the enzymatic regulation of chemical signaling.  Please reserve Wednesday, May 24th, on your calendars for this event. Location TBA.


Volunteer Opportunities

Happy New Year!

As promised in last newsletter, here is a short list of some diverse ways to get involved volunteering in and around Vanderbilt. If you are concerned about the commitment, I would encourage you to find a friend to go/sign up together. I tried to highlight opportunities which have minimal commute time. It can be hard to remember amidst committee meetings, qualifying exams, paper writing, and thesis preparation, but being a student is the ultimate gift as we are the beneficiaries of those who have come before leaving us with a debt we cannot pay back, only forward.

 

Vanderbilt Student Volunteers for Science

VSVS is a service organization composed of undergraduate, graduate, and medical students who are committed to bringing inquiry-based, hands-on science lessons to middle-school students.

Our goals include to provide Vanderbilt students with an opportunity to explain science to school children, to help college students recognize their responsibilities for community service and the importance of volunteer service in schools, to provide role models for school children and to stimulate an interest in teaching as a profession.

Website: https://studentorg.vanderbilt.edu/vsvs/

Spring 2017 Application due Thursday, Jan 19th at Midnight

 

PenPals with a Purpose

An organization part of the Graduate Student Council which facilitates a letter exchange between graduate students and local middle school students.    Letters are exchanged once a month culminating with a field trip to Vanderbilt sometime in May to meet the pen pals.  The emphasis is on building connections to inspire young students in their studies through relationships.

Website: https://anchorlink.vanderbilt.edu/organization/penpals

Program begins in August/September each fall. Contact gsc_community@vanderbilt.edu

 

Volunteer at Monroe Carell Jr. Children's Hospital at Vanderbilt

Right in our backyard, volunteering at the Children's Hospital is a great way to give back to the Vanderbilt community.  There are a myriad of positions and job types available and not all require working with children.  If you are a virtuoso on an instrument, they can use musicians. This may explain curious sightings of Bruce Damon with a mandolin case.  If you like the medical side of the hospital, consider volunteering for the inpatient acute care units.  If your talents are more on par with mine, they can happily use someone to push the book cart.  Applications come due soon!

Website: http://www.childrenshospital.vanderbilt.org/guide.php?mid=109

Online Application - January 2 - 13

 

Vanderbilt University Women in Science and Engineering (VU-WiSE)

Headed by our very own Abigail Searfoss.

Vanderbilt University Women in Science and Engineering (VU-WiSE) aims to develop a community of women in STEM and their supporters. We work to support the personal and professional development of these women at all levels of their careers (undergraduate through faculty and staff), through networking, mentoring, seminars, outreach, and other events focused on professional development. Follow our events by joining us on Anchor Link or liking our Facebook page!

Websites:

https://anchorlink.vanderbilt.edu/organization/vuwise

https://www.facebook.com/VUWISE/

https://medschool.vanderbilt.edu/vuwise/

 

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Room in the Inn, teaching science to the homeless.

One of the coolest outreach programs started by a graduate student here at Vanderbilt!

Interested in teaching or outreach? Join us on Saturday, January 21st from 9-1130 AM. Volunteers can choose to prepare lectures, lead discussions, or help with demonstrations. Each class will be 45 minutes. Class attendees are all adult participants at Nashville's homeless shelter Room in the Inn. This is an excellent opportunity to hone your science communication skills! Please contact Amanda (amanda.m.duran@vanderbilt.edu) to sign up! Additional tutoring and teaching opportunities are also available at Room at the Inn - please contact Amanda for more details.

 


Opportunities and Events

The Graduate Student Conference on The Aesthetics of Surveillance: Biomedical Ethics & Privacy Roundtable is recruiting short student abstracts to take part in an exciting Vanderbilt roundtable discussion on ethics and privacy in biomedical research. Graduate students from all departments are welcome to participate, and the discussion will be moderated by Ellen Wright Clayton: Vanderbilt professor of Law, Health Policy, and Human Genetics along with Lutz Koepnick: Vanderbilt Professor of German, Cinema and Media Arts.

 

Are you a graduate student in the CPB program? Do you shop on Amazon? If you answered yes to those questions, you're in luck! New in 2017, CPB will be doing a raffle biannually for an Amazon gift card. All you have to do in attend the Lunch & Learn series and scheduled dissertations! Keep an eye out for a card swiper or sign in sheet at future events.


Recent Publications

Juttukonda MR, Jordan LC, Gindville MC, Davis LT,Watchmaker JM, Pruthi S, Donahue MJ. Cerebral hemodynamics and pseudo-continuous arterial spin labeling considerations in adults with sickle cell anemia. NMR in biomedicine. 2017 Jan 4.

Watchmaker JM, Juttukonda MR, Davis LT, Scott AO, Faraco CC, Gindville MC, Jordan LC, Cogswell PM, Jefferson AL, Kirshner HS, Donahue MJ.Hemodynamic mechanisms underlying elevated oxygen extraction fraction (OEF) in moyamoya and sickle cell anemia patients.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2017 Jan 1.

Perreault, A. A., Venters, B. J. The ChIP-exo Method: Identifying Protein-DNA Interactions with Near Base Pair Precision. J. Vis. Exp. (118), e55016, doi:10.3791/55016 (2016).


If you have any news or information to share with the CPB community, please let us know.

Chemical & Physical Biology Program

 

December 2016


If you have difficulty seeing this newsletter in your email reader, you can view it online.

Contents for this Issue

We welcome your comments on this newsletter and would like to hear about all of your good news and progress; please contact Michaela Fooksa or Christian Meyer with details.  You can also learn about the dates of all upcoming events on the CPB website, the GSA's Google Calendar, and the GSA's Facebook page (where, after liking the page, you can also share your memories and thoughts). 


Message From the President

Hey all,

Welcome to December! Whether this season represents one of stress and anxiety or festive celebration and thanksgiving, both can benefit from the chance to serve in your community. I hope to put together a list for the next newsletter of volunteer opportunities in and around Vanderbilt, but please consider working out some anxiety or paying forward your many gifts by volunteering through Hands On Nashville this holiday season.

The CPB GSA wishes you a very happy holiday season. Stay safe and take care of one another.

Christian


CPB Holiday Party

The CPB Holiday Party will take place this Thursday, December 8 at Bruce Damon's house. Wear your best ugly sweater and enjoy food and refreshments!


Opportunities and Events

The Chateaubriand Fellowship call for applications is now open: http://www.chateaubriand-fellowship.org.Complete applications must be submitted by January 27, 2017.

The Chateaubriand Fellowship is a grant offered by the Embassy of France in the United States. It supports outstanding Ph.D. students from American universities who wish to conduct research in France for a period ranging from 4 to 9 months. Chateaubriand fellows are selected through a merit-based competition, through a collaborative process involving expert evaluators in both countries.

The CPB Retreat will take place sometime around May 2017. Stay tuned for more details!


Recent Publications

Tang D, Li J, Buck JR, Tantawy MN, Xia Y, Harp JM, Nickels ML, Meiler J, Manning HC. Evaluation of TSPO PET Ligands [18F]VUIIS1009A and [18F]VUIIS1009B: Tracers for Cancer Imaging. 2016 Nov 16.PMID: 27853987


If you have any news or information to share with the CPB community, please let us know.

Chemical & Physical Biology Program

 

November 2016


If you have difficulty seeing this newsletter in your email reader, you can view it online.

Contents for this Issue

We welcome your comments on this newsletter and would like to hear about all of your good news and progress; please contact Michaela Fooksa or Christian Meyer with details.  You can also learn about the dates of all upcoming events on the CPB website, the GSA's Google Calendar, and the GSA's Facebook page (where, after liking the page, you can also share your memories and thoughts). 


Lunch and Learn

This month's Lunch and Learn will take place Thursday, November 10 in Light Hall 411 A/B.Dr. David Sacks will discuss Excelling Under Pressure: Lessons from Expert Performers.

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CPB Holiday Party

The CPB Holiday Party will take place on Thursday, December 8 at Bruce Damon's house. More details TBD!


Opportunities and Events

AIMBE is offering one-year regulatory policy appointments to postdoctoral scholars with advanced training in medical and biological engineering. Scholars work side-by-side with influential decision makers in the Center for Devices and Radiological Health in Washington, DC. This is a highly competitive program with an 8.5% acceptance rate. AIMBE is soliciting applications for its October 1, 2017 to September 30, 2018 program year. Scholars are provided with a $70,000 stipend and allowances for moving expenses and participation in scientific conferences. Applications deadline is December 5, 2016 (doctoral-level degrees must be conferred by August 2017). More information is available at: aimbe.org/scholars-program/.

 

On Monday, November 14, Professor Xiu Cravens will be talking about women in the global university as part of the Women in the Academy Series. Lunch is provided!

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Recent Publications

Simmons AJ, Scurrah CR, McKinley ET, Herring CA, Irish JM, Washington MK, Coffey RJ, Lau KS. Impaired coordination between signaling pathways is revealed in human colorectal cancer using single-cell mass cytometry of archival tissue blocks. 2016 Oct 11. PMID: 27729552

Poorman ME, Chaplin VL, Wilkens K, Dockery MD, Giorgio TD, Grissom WA, Caskey C. Erratum to: Open-source, small-animal magnetic resonance-guided focused ultrasound system. 2016 Oct 19. PMID: 27777767

Choby JE, Mike LA, Mashruwala AA, Dutter BF, Dunman PM, Sulikowski GA, Boyd JM, Skaar EP. A Small-Molecule Inhibitor of Iron-Sulfur Cluster Assembly Uncovers a Link between Virulence Regulation and Metabolism in Staphylococcus aureus. 2016 Oct 20. PMID: 27773628

Wu SY, Zou P, Fuller AW, Mishra S, Wang Z, Schey KL, Mchaourab HS. Expression of Cataract-linked γ-crystallin Variants in Zebrafish Reveals a Proteostasis Network that Senses Protein Stability. 2016 Oct 21. PMID: 27770023

Ostenson J, Pujara Ac, Mikheev A, Moy L, Kim SG, Melsaether AN, Jhaveri K, Adams S, Faul D, Glielmi C, Geppert C, Feiweier T, Jackson K, Cho GY, Boada FE, Sigmund EE. Voxelwise analysis of simultaneously acquired and spatially correlated 18 F-fluorodeoxyglucose (FDG)-PET and intravoxel incoherent motion metrics in breast cancer. 2016 Oct 25. PMID: 27779790

Mousa JJ, Sauer MF, Sevy AM, Finn JA, Bates JT, Alvarado G, King HG, Loerinc LB, Fong RH, Doranz BJ, Correia BE, Kalyuzhniy O, Wen X, Jardetzky TS, Schief WR, Ohi MD, Crowe JE JR. Structural basis for nonneutralizing antibody competition at antigenic site II of the respiratory syncytial virus fusion protein. 2016 Nov 1.PMID: 27626297


If you have any news or information to share with the CPB community, please let us know.

Chemical & Physical Biology Program

 

October 2016


If you have difficulty seeing this newsletter in your email reader, you can view it online.

Contents for this Issue

We welcome your comments on this newsletter and would like to hear about all of your good news and progress; please contact Michaela Fooksa or Christian Meyer with details.  You can also learn about the dates of all upcoming events on the CPB website, the GSA's Google Calendar, and the GSA's Facebook page (where, after liking the page, you can also share your memories and thoughts). 


Lunch and Learn

This month's Lunch and Learn will take place Thursday, October 13 in 411 Light Hall A/B. 

Bruce Damon wil be speaking on Managin the Endgame: Steps in Completing your PhD and Setting up the Next Step. CPB students - especially students within 12 months of completion - are encouraged to attend this presentation about the steps involved in completing their PhD degree, receive advice about writing, and how to set up their next step.

Endgame.jpg


Events

CPB Social Hour

Join us for a social hour on Wednesday, October 19th from 5-7 PM in the student lounge on the third floor of Light Hall.

Food and beverages will be served!

CPB Hike

See the photo below from the CPB Hike at Radnor Lake on October 1!

IMG_2830_1.JPG


Student Travel

This past month,we had several students travel for exciting conferences and opportunities.

Jason Ostenson went to two workshops, and he had the following to say about his experience:

I was recently fortunate to attend two weeklong training workshops for magnetic resonance imaging (MRI) in Cleveland, Ohio. The Vanderbilt University Institute of Imaging Science (VUIIS) has two 3 Tesla Philips Achieva human MRI systems with proprietary software. With this training I was allowed to see “under the hood” at tools used for sequence development on these scanners, as well as manipulate the source code that runs the scanners on research protocols. This training will allow me to further improve sequence development and image analysis for better quantification of tissue phenotype using MRI.

Vandiver Chaplin went to the Focused Ultrasound Foundation Symposium in Washington, DC and the World Molecular Imaging Congress in New York City. He also went to the NIBIB Training Grantees Meeting.


Recent Publications

Donahue MJ, Juttukonda MR, Watchmaker JM. Noise concerns and post-processing procedures in cerebral blood flow (CBF) and cerebral blood volume (CBV) functional magnetic resonance imaging. 2016 Sep 11.PMID: 27622397

Poorman ME, Chaplin VL, Wilkens K, Dockery MD, Giorgio TD, Grissom WA, Caskey CF. Open-source, small-animal magnetic resonance-guided focused ultrasound system. J Ther Ultrasound. 2016 Sep 5;4(1):22.PMID: 275978895

Bender BJ, Cisneros A, Duran AM, Hinn JA, Lokits AD, Mueller BK, Sangha AK, Sauer MF, Sevy AM, Sliwoski G, Sheehan JH, DiMaio F, Meiler J, Moretti R. Protocols for Molecular Modeling with Rosetta3 and RosettaScripts 2016 Aug 30.PMID: 27490953

Surdel MC, Dutter BF, Sulikowski GA, Skaar EP. Bacterial Nitric Oxide Synthase Is Required for the Staphylococcus aureus Response to Heme Stress. 2016 Aug 12.PMID: 27626297


If you have any news or information to share with the CPB community, please let us know.

Chemical & Physical Biology Program

 

September 2016


If you have difficulty seeing this newsletter in your email reader, you can view it online.

Contents for this Issue


Welcome Message

Greetings! I’d like to start by thanking last year’s CPB Graduate Student Association officers once again for all of their hard work. In addition to planning the retreat and regular social activities, they took the initiative to start two important new activities for our program – the monthly publication of this newsletter and the Lunch and Learn seminar series. I am confident that this year’s officer class will be just as outstanding, and I look forward to working with them.

As you read below, you’ll see that the September Lunch and Learn seminar is coming up quickly, as Christian Meyer shares his expertise in figure development. This is a skill that all of us require, so I hope that we will see a full turnout.  Looking forward to October, the Lunch and Learn will be of interest to all, but especially for senior students as we discuss career planning for your next step and how to wrap up your disseration research.  Be certain to RSVP so that we have plenty of food. 

Thanks again for your interest in the CPB, and I hope to see you at an upcoming event!

Bruce


We welcome your comments on this newsletter and would like to hear about all of your good news and progress; please contact Michaela Fooksa or Christian Meyer with details.  You can also learn about the dates of all upcoming events on the CPB website, the GSA's Google Calendar, and the GSA's Facebook page (where, after liking the page, you can also share your memories and thoughts). 


Upcoming Events and Opportunities

Lunch and Learn 

This month's Lunch and Learn will take place Thursday, September 15 at 12:00.

Selection_211.png

Garcia Barrantes Defense

GarciaDefense.png

 

CPB Hike

Join the CPB for a hike at Radnor Lake State Park on October 1!

 

Opportunities for Student Involvement

Do you love to teach? Vanderbilt Programs for Talented Youth will soon begin accepting proposals to teach for its 2017 summer programs. Our classes provide academically talented students opportunities to take advanced classes taught by a Vanderbilt professors and graduate students.
 
Tentative dates for our summer 2017 sessions are from June 12-July 28. Classes meet from about 9-4 each day and can last from 1-3 weeks, depending on the program. To learn more about teaching at PTY, visit pty.vanderbilt.edu/teach or send an email to david.j.dunn@vanderbilt.edu

 

 

AIMBE is offering one-year regulatory policy appointments to postdoctoral scholars with advanced training in medical and biological engineering. Scholars work side-by-side with influential decision makers in the Center for Devices and Radiological Health in Washington, DC. This is a highly competitive program with an 8.5% acceptance rate.
 
AIMBE is soliciting applications for its October 1, 2017 to September 30, 2018 program year. Scholars are provided with a $70,000 stipend and allowances for moving expenses and participation in scientific conferences. Applications deadline is December 5, 2016 (doctoral-level degrees must be conferred by August 2017). More information is available at: aimbe.org/scholars-program/.
 
Prospective applicants are encouraged to attend AIMBE's Public Policy Institute for Rising Leaders on October 24-25 in Washington.


Election Results

Congratulations to all the new members of the CPB GSA!

President: Christian Meyer

Treasurer: Lauren Salay

VP of Academic Affairs: Kevin Jagessar

VP of Social Affairs: Andy Perreault

VP of Communications: Michaela Fooksa


Welcome New Students

Welcome to all the new members of the CPB!

Selena Chacon SimonDiego Del AlamoCorey Hayford, ​James M. HutchisonAndrew MorrisNica MarlowTony PhippsAndrea PerreaultIan SetliffJason OstensonMichael PridmoreBenjamin ReismanKalen Petersen


If you have any news or information to share with the CPB community, please let us know.

Chemical & Physical Biology Program

 

August 2016


If you have difficulty seeing this newsletter in your email reader, you can view it online.

Contents for this Issue


Welcome Message

Welcome to the August 2016 CPB newsletter and to the 2015-2016 academic year. Students should note below that the next Lunch and Learn presentation will be on the subject of the new travel policies.  I’m sure that you will want to know about these well in advance of your next conference trip. This will also be a great chance to welcome our twelve new students to the program.

 

Lastly, please be sure to keep us informed of your awards, publications, and other good things.

Bruce 


We welcome your comments on this newsletter and would like to hear about all of your good news and progress; please contact James Pino or Sanjay Mishra with details.  You can also learn about the dates of all upcoming events on the CPB website, the GSA's Google Calendar, and the GSA's Facebook page (where, after liking the page, you can also share your memories and thoughts). 


Upcoming Events and Opportunities

 

Lunch and Learn followed by GSA elections

Lunch and LEARN with Patty Mueller.png

Traveling with science? 

Then you should really check out the new VU Travel Policy.  There may be changes you were not aware of. Many of you are new to your programs and as you start to look at travel both domestic and international, t is important you be aware of the sections which pertain to you.

https://finance.vanderbilt.edu/travel/files/VUTravelPolicy

 

CPB Poster Day

This year the CPB poster day presentation for incoming QCB/IGP students will be held on August 22nd from 1 to 3:30 PM. It is in the north lobby of Light Hall. 

 


2016 CPB Retreat

This years retreat went perfectly according to plan! Thanks to everyone who presented, the retreat planning committee, and especially Sanjay for pulling it all together. 

wdmp_160608_02835.jpg

 


Publications, honors and achievements

Publications

Dutter BF, Mike LA, Reid PR, Chong KM, Ramos-Hunter SJ, Skaar EP, Sulikowski GA. Decoupling Activation of Heme Biosynthesis from Anaerobic Toxicity in a Molecule Active in Staphylococcus aureus. ACS chemical biology. 2016 May 20;11(5). 1354-61.PMID: 26890615


If you have any news or information to share with the CPB community, please let us know.

Chemical & Physical Biology Program

 

May 2016


If you have difficulty seeing this newsletter in your email reader, you can view it online.

Contents for this Issue


Welcome Message

Hello CPB Community,
This months newsletter highlights our graduate students. Over the last year 9 students have successfully passed their qualifying exams, the GSA has successfully started a new lunch and learn series and newsletter, and now we are happy to announce we have acquired AcFee funding from the university. This will allow us to continue the Lunch and Learn Series as well as possible add more events in the coming year. The GSA would like to thank Bruce and Patty for allowing and allocating funding for the Lunch and Learn Series until now.  I do think it has been a success and we are proud of the initiative.


Next month we have our retreat. We will be coming out with a schedule of the day which will be on the website soon. Remember, students are REQUIRED to attend. We look forward to Professor Roger Craig visit and talk, as well as catching up on the research from our fellow students over the past year.


Until next time,
James Pino

 


We welcome your comments on this newsletter and would like to hear about all of your good news and progress; please contact James Pino or Sanjay Mishra with details.  You can also learn about the dates of all upcoming events on the CPB website, the GSA's Google Calendar, and the GSA's Facebook page (where, after liking the page, you can also share your memories and thoughts). 

 


News

 

CPB AcFee

CPB GSA now has AcFee funds! Special thanks to Abigail Searfoss! This will help us continue programs and allow us to add on more, such as Lunch and Learn series.

 

PhD Candidates

Congratulations to those who have passed their qualifying exam and moved to the next stage in their graduate careers.

Austin Oleskie 
Kelly Gardner
Vandiver Chaplin 
Jennifer Watchmaker
James Pino 
Chuck Herring  
Alex Sevy 
Abigail Searfoss 
Myriam Diaz

 


Upcoming Events and Opportunities

Defense

Dutter , Defense Announcement Revised Date[1] copy.jpg

 

Upcoming survey

Next months newsletter will come with a link to a survey. The CPB GSA would like feedback over the last year. Our new initiatives include the Lunch and Learn Series and the monthly newsletter.

Next years CPB GSA elections will be held sometimes in August. Would you like to make a difference? Do you have ideas about improving the CPB environment?  Not only does one gain leadership, management, and planning  experience, it is also a fun and rewarding environment.  

 


2016 CPB Retreat

June 8th is right around the corner! Please view the tentative schedule of the retreat.

Remember, 3rd year students are required to give 15 minute talks, while all other students are required to give poster presentation. Remember, this years CPB program's retreat will occur on June 8th this year. 

This year, the keynote presentation rotates to the Structural Biology track, and we are happy to announce that Professor Roger Craig of UMass Medical School in Worcester MA will be our keynote speaker.  

Dr. Craig has had a long and distinguished career investigating the structural biology and biophysics of muscle proteins, and we will surely enjoy both his scientific presentation and hearing his advice to students.

If you would like to assist in the planning of the retreat, please e-mail Sanjay Mishra. 

Look here for a summary of previous retreats.

 

 


Student Lead Initiatives

Researchers for Collaborative Success

A new program was started this semester by one of our CPB students, Myriam Diaz Martinez. The program is called "Researchers for Collaborative Success". 

Here is some information about the program. Please see the website to see the list of events and outings that are planned.

 

Our Mission is to build a community of passionate researchers that continuously strive for their unique successful work-life design.

We primarily aim to provide mentoring for the struggles that arise in graduate school and continue through a career in Academia—many originated by its inherent nature:

  1. Perpetual stress
  2. Hard work followed by setbacks
  3. Rare acknowledgement
  4. Learning to interpret ruthless criticism as positive feedback
  5. Lost enthusiasm about your involvement in the development of knowledge

Researchers for Collaborative Success is committed to help researchers to achieve fulfillment in their leadership positions in Academia, and help them achieve well-roundedness in their own work-life design. Our plan to reach collaborative success involves three strategies: community building, impactful mentoring and professional development. 
If you would like to learn more about us, please check our website


Follow Us On Social Media!
Facebook: https://www.facebook.com/groups/1142745699111408/
Twitter:      https://twitter.com/R4CollabSuccess
Instagram: https://www.instagram.com/R4CollabSuccess
 

-Myriam

 


Publications, honors and achievements

Publications

Harris LA, Frick PL, Garbett SP, Hardeman KN, Paudel BB, Lopez CF, Quaranta V, Tyson DR. An unbiased metric of antiproliferative drug effect in vitro. Nature methods. 2016 May 2. PMID: 27135974

Gogliotti RD, Engers DW, Garcia-Barrantes PM, Panarese JD, Gentry PR, Blobaum AL, Morrison RD, Daniels JS, Thompson AD, Jones CK, Conn PJ, Niswender CM, Lindsley CW, Hopkins CR. Discovery of 3-aminopicolinamides as metabotropic glutamate receptor subtype 4 (mGlu4) positive allosteric modulator warheads engendering CNS exposure and in vivo efficacy. Bioorganic & medicinal chemistry letters. 2016 Apr 19. PMID: 27131990

 


If you have any news or information to share with the CPB community, please let us know.


 

SACS Reporting 

Want to meet all requirements for a qualifying exam?

Committee meeting coming up? 

Do you want to eventually graduate?

If you answered yes to any of these questions you are going to want to make sure you remember that all the required forms are located online through REDCap.  All students have been enrolled in a REDCap project entitled, “CPB SACS.”  A link on our CPB website provides detailed instructions for how to join that project, fill in basic information about your committee membership, and send a survey link to your committee chair for completion at your qualifying exam, committee meeting, or defense.

Please plan to review the instructions and complete the process of sending the survey link well in advance of your next meeting; if you need additional guidance, please contact Patty Mueller, CPB’s Program Manager.

 

 

Chemical & Physical Biology Program

 

April 2016


If you have difficulty seeing this newsletter in your email reader, you can view it online.

Contents for this Issue


Program Director’s Message


To start, I'd like to thank Gregor Neuert, Marilyn Holt, and Mark dela Cerna for representing the CPB during the March IGP graduate student recruitment weekends. Also, I'd like thank CPB alumna Dr. Aliya Gifford for her outstanding Lunch & Learn presentation on using Linked In, Meetups, and other modern tools for searching for jobs in the private sector. Not to mention our outstanding class of GSA officers.  Voluntary contributions to our program such as these make a significant difference to the culture and community of our program.
We have a lot to look forward to in the weeks and months ahead: another Lunch & Learn seminar; our annual retreat; an upcoming PhD defense.  Read on to learn about these things, plus some of the other good things that our students have accomplished.
 

Bruce


We welcome your comments on this newsletter and would like to hear about all of your good news and progress; please contact James Pino or Sanjay Mishra with details.  You can also learn about the dates of all upcoming events on the CPB website, the GSA's Google Calendar, and the GSA's Facebook page (where, after liking the page, you can also share your memories and thoughts). 

 


 

Lunch and Learn 

Lunch and LEARN with Bruce Damon.PNG

 

Please RSVP  ! As always lunch will be provided.


2016 CPB Retreat

Please register and submit your abstract to the retreat through RedCap.  Abstracts are due April 30th. Faculty, please register here. Remember, 3rd year students are required to give 15 minute talks, while all other students are required to give poster presentation. Remember, this years CPB program's retreat will occur on June 8th this year. 

This year, the keynote presentation rotates to the Structural Biology track, and we are happy to announce that Professor Roger Craig of UMass Medical School in Worcester MA will be our keynote speaker.  

Dr. Craig has had a long and distinguished career investigating the structural biology and biophysics of muscle proteins, and we will surely enjoy both his scientific presentation and hearing his advice to students.

If you would like to assist in the planning of the retreat, please e-mail Sanjay Mishra. 

Look here for a summary of previous retreats.

 


Upcoming Events and Opportunities

CPB Qualifying Exam Q&A

April 12th 4-5pm in 736 RRB

Come chat with those who have made it to the other side! Open discussion gives you an opportunity to ask any questions about the process of choosing a committee and preparing for the qualifying exam. We look forward to seeing you!

Defense

Dutter , Defense Announcement Revised Date[1] copy.jpg

Fellowship Opportunities

The Vanderbilt Institute for Digital Learning (VIDL) is pleased to announce the 2016-17 Graduate Fellows Program application is available on our website.  This year’s deadline is April 22nd.
Graduate Fellows Program: VIDL invites applications for graduate student fellowships for the 2016-2017 academic year. Stipends will be $5,500 per academic year (this is intended to reflect a roughly 5-hour commitment weekly). Graduate Fellows of VIDL will advance scholarship in digital learning as well as learn about the many aspects of creating and evaluating digital learning content.

 

VICB Prize for Excellence in Chemical Biology Research at the Doctoral Level

The prize will be awarded to a graduate student who has conducted exceptional research in the area of chemical biology. A $1,000 honorarium and plaque will be awarded at the Annual VICB Student Research Symposium.

Deadlines:
Submission of the application package: May 1 Interview: May (TBD)
Notice of award: Two days after interview
Award of the prize & oral presentation: August 17, 2016 

 

Scholarly Communications Workshops

Learn new tools and techniques in the field of scholarly communications and digital scholarship. See the schedule and workshop descriptions. They are at 11 a.m. on Fridays in Room 418a in the Central Library.


Publications, honors and achievements

Publications

Garcia-Barrantes PM, Cho HP, Blobaum AL, Niswender CM, Conn PJ, Lindsley CW. Lead optimization of the VU0486321 series of mGlu1 PAMs. Part 3. Engineering plasma stability by discovery and optimization of isoindolinone analogs.Bioorganic & medicinal chemistry letters. 2016 Apr 15;26(8). 1869-72.PMID: 26988302 [PubMed].


Fischer AW, Heinze S, Putnam DK, Li B, Pino JC, Xia Y, Lopez CF, Meiler J. CASP11 - An Evaluation of a Modular BCL::Fold-Based Protein Structure Prediction Pipeline. PloS one. 11(4). e0152517. Link


Chong KM, Leelatian N, Deguire SM, Brockman AA, Earl D, Ihrie RA, Irish JM, Bachmann BO, Sulikowski GA.  The use of fluorescently-tagged apoptolidins in cellular uptake and response studies. The Journal of antibiotics. 2016 Mar 9.PMID: 26956792 [PubMed].

Cheng F, Zhao J, Zhao Z.  Fooksa M.  A network-based drug repositioning infrastructure for precision cancer medicine through targeting significantly mutated genes in the human cancer genomes. Journal of the American Medical Informatics Association : JAMIA. 2016 Mar. PMID: 27026610 [PubMed].

Honors

Congratulations to Christian Meyer on being award an NSF graduate fellowship.

christian.png

Christian also returned from a trip to the Keynote Symposian. Here is his experience.

"Held in Keystone Colorado in a foot of snow, this joint meeting was designed to serve in promoting the sharing of unpublished work relating to a variety of topics relating to Islet Biology and Stem Cells in Digestive Organs.  Workshops included topics included regenerative medicine in diabetes; differential lineage commitment of the GI track stem cells; tissue engineering; beta cell function, proliferation, and survival in disease states; and functional cell reprogramming in multiple tissues.  Keynote speakers for the meeting were Hiromitsu Nakauchi of Stanford who discussed his decade long project on chimeras for growing human organs in pigs and Hans Clever who presented the function and flexibility of the Lgr5+ stem cell of the intestinal crypt." -- Christian

Picture1.png

 

Congratulations to Christian and thanks for the summary and pictures. 

 


If you have any news or information to share with the CPB community, please let us know.


 

SACS Reporting 

Want to meet all requirements for a qualifying exam?

Committee meeting coming up? 

Do you want to eventually graduate?

If you answered yes to any of these questions you are going to want to make sure you remember that all the required forms are located online through REDCap.  All students have been enrolled in a REDCap project entitled, “CPB SACS.”  A link on our CPB website provides detailed instructions for how to join that project, fill in basic information about your committee membership, and send a survey link to your committee chair for completion at your qualifying exam, committee meeting, or defense.

Please plan to review the instructions and complete the process of sending the survey link well in advance of your next meeting; if you need additional guidance, please contact Patty Mueller, CPB’s Program Manager.

 

 

Chemical & Physical Biology Program

 

March 2016


If you have difficulty seeing this newsletter in your email reader, you can view it online.

Contents for this Issue


Program Director’s Message

February was a great month for the CPB!  First and foremost, we were delighted to hear from Prof. Hassane Mchaourab as he delivered the inaugural Leaders in Chemical and Physical Biology Seminar.  We were also pleased to be able to thank him for his many contributions to the program since its inception.  Thanks to Hassane for his presentation and too all who attended.  This month, we also saw CPB student Pooja Gaur (now Dr. Gaur!) successfully defend her dissertation, "Advancements in MRI Temperature Map Reconstruction for Real-Time Guidance of Thermal Therapies."  Pooja conducted her research under the direction of Will Grissom, with Brian Welch serving as her Chair.  Congratulations also to all those students who applied for and received travel awards from the Graduate School of other sources.

I'd also like to extend my thanks to Ken Lau, Chuck Herring, Pedro Garcia, Sanjay Mishra, and Vandiver Chaplin for representing the CPB at the IGP program primer events.  I greatly appreciate the time that you offered to the CPB program, the IGP program, and the School of Medicine's graduate programs as a whole. 

Read on to see what March has in store!

Bruce

 


We welcome your comments on this newsletter and would like to hear about all of your good news and progress; please contact James Pino or Sanjay Mishra with details.  You can also learn about the dates of all upcoming events on the CPB website, the GSA's Google Calendar, and the GSA's Facebook page (where, after liking the page, you can also share your memories and thoughts). 

 


 

Lunch and Learn 

 

Lunch and LEARN with Aliya Gifford.png

Please RSVP! As always lunch will be provided.


Upcoming Events and Opportunities

 

 

PhD Career Connections: Working at the CDC

Featuring Jennifer Anstadt, PhD; Team Lead Microbiologist, Vaccine Development Laboratory

Friday, March 11

9:00-10:00am

Light Hall 214

 

ASPIRE to Connect: A2C gets Cheeky!

Featuring Isaiah Haynes, the Cheeky Scientist

Monday, March 14

1:00 - 4:00 pm

Light Hall 208

 

 

Scholarly Communications Workshops

Learn new tools and techniques in the field of scholarly communications and digital scholarship. See the schedule and workshop descriptions. They are at 11 a.m. on Fridays in Room 418a in the Central Library.


2016 CPB Retreat

Within the next month we will send out a link to submit abstracts for this years CPB retreat. 3rd year students are required to give 15 minute talks, while all other students are required to give poster presentation. Remember, this years CPB program's retreat will occur on June 8th this year. 

This year, the keynote presentation rotates to the Structural Biology track, and we are happy to announce that Professor Roger Craig of UMass Medical School in Worcester MA will be our keynote speaker.  

Dr. Craig has had a long and distinguished career investigating the structural biology and biophysics of muscle proteins, and we will surely enjoy both his scientific presentation and hearing his advice to students.

If you would like to assist in the planning of the retreat, please e-mail Sanjay Mishra. 

Look here for a summary of previous retreats.

 


Publications, honors and achievements

Publications

Pedro Garcia-Barrantes has recently published a pair of papers titled Lead optimization of the VU0486321 series of mGlu1 PAMs. Part 2: SAR of alternative 3-methyl heterocycles and progress towards an in vivo tool and Lead optimization of the VU0486321 series of mGlu1 PAMs. Part 1: SAR of modifications to the central aryl core. 

 

Development of mGlu1 positive allosteric modulators (PAM)

Recently, we have published on Medicinal chemistry efforts to develop novel mGlu1 PAMs. These new chemical tools would allow to explore the role of the mGlu1 receptor in different neuropsychiatric disorders, opening the door for target validation studies.

This two articles describe the chemical modifications performed on the lead compound VU0486321, in order to optimize its selectivity profile and pharmacokinetic properties, specially its free fraction in plasma and half-life in animals.

The first paper, entails the modifications in the central phenyl ring of VU0486321 and the discovery that a single removal of a chlorine and replacement for fluorine, render the molecule completely selective for mGlu1 with respect to mGlu4 and mGlu5, our main anti-targets. In the second paper, we describe different substitutions to improve the polar surface area of the molecules in order to achieve better plasma free fraction, and modifications on the phthalimide that allow for the discovery of VU6004909, a selective mGlu1 PAM that increase the half-life of close to 5 hours, improving the stability of the compound 5-fold.

- Pedro 

Honors

Jennifer Watchmaker : Midwest American Physician Scientist Education Program's Student Travel Award to the Clinical Interventional Oncology Symposium.

Austin Oleskie : Graduate Student Travel award - Biophysical Society Annual Meeting in Los Angeles.

Christian Meyer : Graduate Student Travel award -  Islet Biology: From Cell Birth to Death, Keystone Symposium.

Pooja Gaur : 2016 International Society for Therapeutic Ultrasound Symposium in Tel Aviv.

 

 

 

SACS Reporting 

Want to meet all requirements for a qualifying exam?

Committee meeting coming up? 

Do you want to eventually graduate?

If you answered yes to any of these questions you are going to want to make sure you remember that all the required forms are located online through REDCap.  All students have been enrolled in a REDCap project entitled, “CPB SACS.”  A link on our CPB website provides detailed instructions for how to join that project, fill in basic information about your committee membership, and send a survey link to your committee chair for completion at your qualifying exam, committee meeting, or defense.

Please plan to review the instructions and complete the process of sending the survey link well in advance of your next meeting; if you need additional guidance, please contact Patty Mueller, CPB’s Program Manager.

 

 

Chemical & Physical Biology Program

 

February 2016


If you have difficulty seeing this newsletter in your email reader, you can view it online.

Contents for this Issue


Program Director’s Message

Greetings! I’d like to start by highlighting two important dates:

  • Thursday, February 18: Hassane Mchaourab will give the inaugural CPB Director’s Seminar, titled “Staying Fit with Molecular Jumping Jacks.” This will be a chance not just to learn about Dr. Mchaourab’s research, but also to pay tribute to him for his many years of service to the program.  The lecture will be held at 4:00 pm in 1220 MRB III, with a reception to follow.

 

  • Wednesday, June 8: the CPB Retreat, with our guest Roger Craig, PhD of UMass Medical School.  In addition to Dr. Craig’s scientific and career-oriented presentations, we will have oral and poster presentations from all of our students.  Registration and abstract submission information will be forthcoming.

In addition, I would like to thank Charles Caskey, Abigail Searfoss, Sanjay Mishra, and Christian Meyer for their help with IGP recruiting events during the month of January.  Any students and faculty who would like to lend an hour or two to the important task of identifying the best graduate student applicants and recruiting them to Vanderbilt may sign up by following this link.  Thanks also go to Vandiver Chaplin for his excellent presentation on science policy during the January Lunch and Learn series.

 

Please read on to learn about the many other upcoming events during February!

 

Best regards,

Bruce Damon

CPB Director


We welcome your comments on this newsletter and would like to hear about all of your good news and progress; please contact James Pino or Sanjay Mishra with details.  You can also learn about the dates of all upcoming events on the CPB website, the GSA's Google Calendar, and the GSA's Facebook page (where, after liking the page, you can also share your memories and thoughts). 


Dissertation Defense

 

bettyann_defense.png

 

 


 

Inaugural CPB Director’s Seminar 

On February 18, Hassane Mchaourab will give the inaugural CPB Director’s Seminar. We will hold this lecture as an annual event to learn about and learn from the people on campus who contribute to the CPB program’s success.  Hassane was the program’s first DGS, succeeded Al Beth as the Program Director, and continues to contribute to the program as a member of the faculty and on the Executive Advisory Committee.  His talk will be held at 4:00 pm in MRB III, Rm. 1220 and will be followed by a festive reception.


Upcoming Events and Opportunities

 

2016 Vanderbilt 3MT Competition

Three Minute Thesis (3MT®) is a research communication competition which challenges students to present a compelling oration on their thesis and its significance in just three minutes in language appropriate to a non-specialist audience. The Graduate Student Council at Vanderbilt University hosts the annual 3MT at Vanderbilt.

The 2016 3MT Competition is scheduled for Friday February 26th 2016.

Registration is now open at GSC Anchor link page

 

PhD Career Connections: Medical Communications

Featuring Tristin Abair, PhD; Leah Case, PhD; and Kim Korwek, PhD

Friday, February 12

9:00-10:00 am

PRB 206

 

PhD Career Connections: Working at the CDC

Featuring Jennifer Anstadt, PhD; Team Lead Microbiologist, Vaccine Development Laboratory

Friday, March 11

9:00-10:00am

Light Hall 214

 

ASPIRE to Connect: A2C gets Cheeky!

Featuring Isaiah Haynes, the Cheeky Scientist

Monday, March 14

1:00 - 4:00 pm

Light Hall 208

 

 

Scholarly Communications Workshops

Learn new tools and techniques in the field of scholarly communications and digital scholarship. See the schedule and workshop descriptions. They are at 11 a.m. on Fridays in Room 418a in the Central Library.

The next one is Cleaning Up Your Data with OpenRefine.

Friday, February 12

Morgan Daniels

  • Cleaning and preserving a dataset makes it more available for long-term use and sharing with interested colleagues (and can help you meet funding agency requirements for data management!) In this session, we’ll explore the tool OpenRefine and use it to work with a sample dataset. We’ll also talk about simple ways to preserve your research data.

2016 CPB Retreat

VandyRetreat ┬⌐ 2015 Bruce Sweetman 001 copy.jpgThe CPB program's retreat will occur on June 8th this year.  The purposes of the retreat are to afford the program’s students and faculty the opportunity to appreciate the breadth of research that is being conducted in the CPB Program; for students to gain experience in presenting scientific work in a scientifically critical but personally supportive setting; and to foster a sense of community within the program. It is our major program-wide event, and attendance is required of all students. The academic program includes poster and oral presentations from each student and a keynote presentation whose research represents one of the four programmatic tracks. 

This year, the keynote presentation rotates to the Structural Biology track, and we are happy to announce that Professor Roger Craig of UMass Medical School in Worcester MA will be our keynote speaker.  

Dr. Craig has had a long and distinguished career investigating the structural biology and biophysics of muscle proteins, and we will surely enjoy both his scientific presentation and hearing his advice to students.

If you would like to assist in the planning of the retreat, please e-mail Sanjay Mishra. 

Look here for a summary of previous retreats.

 


Publications, honors and achievements

This past month BettyAnn Chodkowski work was featured in the reporter. Her work has showed that brain function in obese children is different than other children. To find out more please check out the article as well as attend her dissertation defense. 

Pedro Garcia-Barrantes has recently published a pair of papers titled Lead optimization of the VU0486321 series of mGlu1 PAMs. Part 2: SAR of alternative 3-methyl heterocycles and progress towards an in vivo tool and Lead optimization of the VU0486321 series of mGlu1 PAMs. Part 1: SAR of modifications to the central aryl core.

 

 

SACS Reporting 

Want to meet all requirements for a qualifying exam?

Committee meeting coming up? 

Do you want to eventually graduate?

If you answered yes to any of these questions you are going to want to make sure you remember that all the required forms are located online through REDCap.  All students have been enrolled in a REDCap project entitled, “CPB SACS.”  A link on our CPB website provides detailed instructions for how to join that project, fill in basic information about your committee membership, and send a survey link to your committee chair for completion at your qualifying exam, committee meeting, or defense.

Please plan to review the instructions and complete the process of sending the survey link well in advance of your next meeting; if you need additional guidance, please contact Patty Mueller, CPB’s Program Manager.

 

 

Chemical & Physical Biology Program

 

January 2016


If you have difficulty seeing this newsletter in your email reader, you can view it online.

Contents for this Issue

Program Director’s Message

Happy New Year!  This month’s newsletter brings exciting student news (the list of 2015 student publications, a conference report, and a pending PhD defense), the announcement of the next “Lunch and Learn” seminar, and other important program news and events.  There are two special issues to which I’d like to call your attention.

  • For faculty: As noted in the recent email, your help is needed in the IGP and QCB recruitment weekends.  Please sign up to help in this important process.  Also, please know that you are welcome at events such as the Lunch and Learn seminars.  It  means a lot to students to see their faculty attend these events.
  • For everyone: Please look for a special email with the guest speaker and date of the 2016 CPB retreat to arrive shortly. 

As always, I am very grateful to the CPB Graduate Students Association officers, who have taken such strong initiative in producing this newsletter and organizing many of the events listed below.  They are doing a truly outstanding job!

 

We welcome your comments on this newsletter and would like to hear about all of your good news and progress; please contact James Pino or Sanjay Mishra with details.  You can also learn about the dates of all upcoming events on the CPB website, the GSA's Google Calendar, and the GSA's Facebook page (where, after liking the page, you can also share your memories and thoughts). 

Bruce Damon

CPB Director


Dissertation Defense

Chodkowski, Defense Announcement.png


Lunch and Learn with Vandiver Chaplin

Please join us for our second "Lunch and Learn" talk:

Lunch and LEARN with Vandiver Chaplin.png

RSVP via Facebook or email

A big shout out to Vandiver for volunteering. Please share your expertise and consider volunteering for future sessions. We intend to host it monthly at around the same time.


Student Experience

Bishal Paudel, a student in Vito Quarantas lab, just returned from the 2015 Society for Melanoma Research Congress. Here is his experience.

I had an opportunity to attend Society for Melanoma Research Congress this last November in San Francisco, CA. Melanoma is an aggressive form of skin cancer with approximately 76000 new cases of diagnosis and 10000 melanoma related death, according to a report by ACS, 2014. Several subtypes of melanoma have been defined based on the mutation status, of which mutations in BRAF, NRAS are the most common. An annual meeting for researchers working on melanoma and related diseases had approximately 1200 attendees which, according to the current president, Dr. Martin McMahon had risen significantly from previous years. This five-day meeting was well attended by researchers from diverse disciplines ranging from clinicians to theoretical scientists to molecular biologists. With approval of small molecule targeted therapies and immune-therapy, melanoma has drawn interests from different groups in understanding the biology, tumor progression, treatment failure, resistance mechanisms, and possible therapeutic interventions to achieve better clinical efficacy. Main theme of the Congress focused on the possible combination of immune therapy and targeted therapies. Keynote speaker, Dr. Antoni Ribas talked about the newly approved immune-therapy, PD-1 blockade and how it induces responses by inhibiting adaptive immune resistance. Other topics included the use of genomic approaches, understanding metabolic diversity in melanomas, inferring heterogeneity both at cell and tissue level, and the use of mathematical modeling to predict clinical outcomes and tumor progression. 

 


Upcoming Events and Opportunities

 

2016 Vanderbilt 3MT Competition

Three Minute Thesis (3MT®) is a research communication competition which challenges students to present a compelling oration on their thesis and its significance in just three minutes in language appropriate to a non-specialist audience. The Graduate Student Council at Vanderbilt University hosts the annual 3MT at Vanderbilt.

The 2016 3MT Competition is scheduled for Friday February 26th 2016.

Registration is now open at GSC Anchor link page

 

BRET Annual Career Symposium 

Mark your calendars for the 2016 BRET Annual Career Symposium

Thu, June 2, 2016
8am – 6pm

The focus this year will be "Research and Development Careers in Industry".


2016 CPB Retreat

VandyRetreat ┬⌐ 2015 Bruce Sweetman 001 copy.jpgThe next CPB retreat will be held on a date to be determined between May 17 and May 31, 2016. Students should plan to be in town during that entire period of time, as their attendance is required at the retreat. This year we are planning to invite a keynote speaker from the field of Structural Biology; the specific date will be determined in conjunction with our speaker's schedule. We invite students to join us for the retreat planning committee; to volunteer for the planning committee, please send an email to Sanjay Mishra.

 


Publications, honors and achievements

There were 20 publications from CPB students in the 2015 year! To view them, check out the new publications section of our website.

We want to know and publicize your publications, honors, and achievement. Please send them our way!


Other News

Patty Mueller has moved offices!

Patty, our Interdisciplinary Program Coordinator, is now located in room 673E in Light Hall. (This is in the Ascano and Hodges Lab).

Reminder, there is an open house on Tuesday the 12th from 9:30 to 10:30 am. There will be bagels! 

Feel free to stop in and say hello!

SACS Reporting Goes Digital

As post-Qual students and their committees are aware, we are required to provide documentation of an ongoing mechanism for student evaluation and progress reporting to our accrediting agency, the Southern Association of Colleges and Schools.  So far, we have been obtaining these data using paper forms and transferring the data manually to a spreadsheet for review and evaluation. We are pleased to announce that this month, we will be switching to a fully digital workflow for this task.  The reasons for this change are to: 

  • Reduce the inefficiencies associated with moving, completing, and submitting the paper forms; 
  • Promote standardization across the committee’s evaluations; 
  • Reduce the inefficiency of requiring the Program Manager to identify missing forms and committee letters manually; and 
  • Simplify the mechanisms for the program leadership to review student progress at regular intervals and to complete the annual SACS reports.

The digital reporting mechanism uses REDCap (Research Electronic Data Capture). All students have been enrolled in a REDCap project entitled, “CPB SACS.”  A link on our CPB website provides detailed instructions for how to join that project, fill in basic information about your committee membership, and send a survey link to your committee chair for completion at your qualifying exam, committee meeting, or defense.

Please plan to review the instructions and complete the process of sending the survey link well in advance of your next meeting; if you need additional guidance, please contact Patty Mueller, CPB’s Program Manager.

 

 

Chemical & Physical Biology Program

 

December 2015


If you have difficulty seeing this newsletter in your email reader, you can view it online.

Contents for this Issue

Program Director’s Message

Season’s Greetings, and welcome to this third edition of the monthly CPB newsletter! This month, we are happy to bring you news of student progress, a holiday gathering, educational opportunities, a new mechanism for SACS reporting, and the 2016 retreat.  I would like to call special attention to two of these items. 
 
First, I would like to recognize Marilyn Holt, who began the CPB Lunch and Learn series with a presentation on the landscape of scientific misconduct – answering the questions, “what are the most common forms of misconduct, and how prevalent is this problem?”  The session was offered for RCR continuing education credit and was very well attended both by members of the CPB and our colleagues from the CBI training grant.  In January, the series will continue with Vandiver Chaplin’s presentation on science policy "Are there beneficial effects of public research funding that can be quantitatively measured?  Don't say 'Yes!' too hastily."; see the news item below for details. I am grateful to the GSA for their initiative in organizing this series, to the presenters, and to those who attended and participated in the session.

Another item to highlight this month is a change in the mechanism for SACS (Southern Association of Colleges and Schools) reporting.  All students who have completed the qualifying exam are familiar with the SACS forms, which are used for student evaluation and progress reporting for our accreditation by SACS.  This month, we will complete the change from paper forms to a fully digital reporting mechanism.  See the news item below for additional details and a link to a presentation about the “nuts and bolts” of this new process.

We welcome your comments on this newsletter and would like to hear about all of your good news and progress; please contact James Pino or Sanjay Mishra with details.  You can also learn about the dates of all upcoming events on the CPB website, the GSA's Google Calendar, and the GSA's Facebook page (where, after liking the page, you can also share your memories and thoughts). 

Bruce Damon, Director


Lunch and Learn with Vandiver Chaplin

Please join us for our second "Lunch and Learn" talk:

"Are there beneficial effects of public research funding that can be quantitatively measured?  Don't say 'Yes!' too hastily." 

We will have pizza! 

Thursday, January 14th 2016
12pm – 1pm
Light Hall 407 C and D

Stay tuned to sign up. 

A big shout out to Vandiver for volunteering. Please share your expertise and consider volunteering for future sessions. We intend to host it monthly at around the same time.


Aliya Gifford’s Dissertation Defense

Join us to listen and support Aliya Gifford from the lab of Brian Welch when defends her dissertation. 

"MRI Characterization of Brown Adipose Tissue in Adult Humans with Validation by PET-CT"

Wednesday, December 9th 2015
10:00 am – 12:00 pm
Room: AA1119-VUIIS

Gifford Dissertation Announcement.png

 

 


Holiday gathering

Happy Holidays CPB!  Join us to celebrate the seasons and welcome the new year. 

Wed, December 16
5pm – 7pm
Light Hall 3rd floor Student Lounge

Please RSVP to Patricia so we know you are coming..

Holiday2015.png

Hope to see everyone there!


Upcoming Events and Opportunities

 

2016 Vanderbilt 3MT Competition

Three Minute Thesis (3MT®) is a research communication competition which challenges students to present a compelling oration on their thesis and its significance in just three minutes in language appropriate to a non-specialist audience. The Graduate Student Council at Vanderbilt University hosts the annual 3MT at Vanderbilt.

The 2016 3MT Competition is scheduled for Friday February 26th 2016.

Registration is now open at GSC Anchor link page

 

BRET Annual Career Symposium 

Mark your calendars for the 2016 BRET Annual Career Symposium

Thu, June 2, 2016
8am – 6pm

The focus this year will be "Research and Development Careers in Industry".


2016 CPB Retreat

VandyRetreat ┬⌐ 2015 Bruce Sweetman 001 copy.jpgThe next CPB retreat will be held on a date to be determined between May 17 and May 31, 2016. Students should plan to be in town during that entire period of time, as their attendance is required at the retreat. This year we are planning to invite a keynote speaker from the field of Structural Biology; the specific date will be determined in conjunction with our speaker's schedule. We invite students to join us for the retreat planning committee; to volunteer for the planning committee, please send an email to Sanjay Mishra.

 


Publications, honors and achievements

Erin Shockley from the lab of Carlos Lopez co-authored a paper recently published in PNAS. 
Competition and allostery govern substrate selectivity of cyclooxygenase-2. 

The paper, the result of collaboration with the Marnett lab at Vanderbilt, focuses on putative allosteric interactions of the enzyme COX-2 with its substrates arachidonic acid and 2-arachidonyl glycerol.  Using a combined experimental and modeling approach, the work supports a model of COX-2 interactions in which turnover of each substrate is modulated by the other substrate.  The use of innovative model calibration methods provided ranges of kinetic constants consistent with the experimental data.

Congratulation to Erin for a great work.

We want to know and publicize your publications, honors, and achievement. Please send them our way!


Other News

Patty Mueller has moved offices!

Patty, our Interdisciplinary Program Coordinator, is now located in room 673E in Light Hall. (This is in the Ascano and Hodges Lab).

Feel free to stop in and say hello!

SACS Reporting Goes Digital

As post-Qual students and their committees are aware, we are required to provide documentation of an ongoing mechanism for student evaluation and progress reporting to our accrediting agency, the Southern Association of Colleges and Schools.  So far, we have been obtaining these data using paper forms and transferring the data manually to a spreadsheet for review and evaluation. We are pleased to announce that this month, we will be switching to a fully digital workflow for this task.  The reasons for this change are to: 

  • Reduce the inefficiencies associated with moving, completing, and submitting the paper forms; 
  • Promote standardization across the committee’s evaluations; 
  • Reduce the inefficiency of requiring the Program Manager to identify missing forms and committee letters manually; and 
  • Simplify the mechanisms for the program leadership to review student progress at regular intervals and to complete the annual SACS reports.

The digital reporting mechanism uses REDCap (Research Electronic Data Capture). All students have been enrolled in a REDCap project entitled, “CPB SACS.”  A link on our CPB website provides detailed instructions for how to join that project, fill in basic information about your committee membership, and send a survey link to your committee chair for completion at your qualifying exam, committee meeting, or defense.

Please plan to review the instructions and complete the process of sending the survey link well in advance of your next meeting; if you need additional guidance, please contact Patty Mueller, CPB’s Program Manager.