Sanjay Mishra

Sanjay Mishra

Vice President of Academic Affairs, PhD Candidate, Molecular Physiology and Biophysics

Light Hall 735


Research Area

Focus of my research is structure - function correlation in sHsp. I am primarily interested in developing animal models of cataract in zebrafish to study the role of lenticular crystallins as sHsp in maintaining native folded state of lens proteins.

Faculty Mentor

Prof. Hassane Mchaourab

Undergraduate Institution

  • Indian Institute of Technology  
  • Lucknow University

Publications

Ybe JA, Fontaine SN, Stone T, Nix J, Lin X, Mishra S (2013) Nuclear localization of clathrin involves a labile helix outside the trimerization domain FEBS Letters 587(2):142-9

Mishra S, Stein RA, and Mchaourab HS (2012) Cataract-linked γD-crystallin mutants have weak affinity to lens chaperones α-crystallins FEBS Letters 586(4):330-6.

Amadi ST, Koteiche HA, Mishra S, and Mchaourab HS.(2010) Structure, dynamics and substrate-induced conformational changes of the multidrug transporter EmrE in liposomes. J Biol Chem 285(34):26710-26718.

Mchaourab HS, Mishra S, Koteiche HA, Amadi SH. (2008)  Role of sequence bias in the topology of the multidrug transporter EmrE.Biochemistry 47(31):7980-7982

Ybe JA, Mishra S, Helms S, and Nixx J .(2007) Crystal structure at 2.8 Å of the DLLRKN-containing coiled-coil domain of Huntingtin-interacting protein 1 (HIP1) reveals a surface suitable for clathrin light chain binding. J Mol Biol 367(1):8-15.

Ybe JA, Ruppel N, Mishra S, and VanHaaften E. (2003) Contribution of cysteines to clathrin trimerization domain stability and mapping of light chain binding. Traffic 4(12):850-856.

Selected Publications