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2019

Su M , Erwin AL , Campbell AM , Pyburn TM , Salay LE , Hanks JL , Lacy DB , Akey DL , Cover TL , Ohi MD , Cryo-EM Analysis Reveals Structural Basis of Helicobacter pylori VacA Toxin Oligomerization Journal of molecular biology. 2019 Apr 05;
Magaret CA , Benkeser DC , Williamson BD , Borate BR , Carpp LN , Georgiev IS , Setliff I , Dingens AS , Simon N , Carone M , Simpkins C , Montefiori D , Alter G , Yu WH , Juraska M , Edlefsen PT , Karuna S , Mgodi NM , Edugupanti S , Gilbert PB , Prediction of VRC01 neutralization sensitivity by HIV-1 gp160 sequence features PLoS computational biology. 2019 Apr 01; 15 (4). e1006952
Sevy AM , Wu NC , Gilchuk IM , Parrish EH , Burger S , Yousif D , Nagel MBM , Schey KL , Wilson IA , Crowe JE , Meiler J , Multistate design of influenza antibodies improves affinity and breadth against seasonal viruses Proceedings of the National Academy of Sciences of the United States of America. 2019 Jan 14; 116 (5). 1597-1602
Soto C , Bombardi RG , Branchizio A , Kose N , Matta P , Sevy AM , Sinkovits RS , Gilchuk P , Finn JA , Crowe JE , High frequency of shared clonotypes in human B cell receptor repertoires Nature. 2019 Feb 13; 566 (7744). 398-402
Paudel BB , Quaranta V , Metabolic plasticity meets gene regulation Proceedings of the National Academy of Sciences of the United States of America. 2019 Feb 08; 116 (9). 3370-3372
Brown BP , Mendenhall J , Meiler J , BCL::MolAlign: Three-Dimensional Small Molecule Alignment for Pharmacophore Mapping Journal of chemical information and modeling. 2019 Feb 12; 59 (2). 689-701
Brown BP , Zhang YK , Westover D , Yan Y , Qiao H , Huang V , Du Z , Smith JA , Ross JS , Miller VA , Ali SM , Bazhenova L , Schrock AB , Meiler J , Lovly CM , On-target resistance to the mutant-selective EGFR inhibitor osimertinib can develop in an allele specific manner dependent on the original EGFR activating mutation Clinical cancer research : an official journal of the American Association for Cancer Research. 2019 Feb 22;
Jordan LC , Juttukonda MR , Kassim AA , DeBaun MR , Davis LT , Pruthi S , Patel NJ , Lee CA , Waddle SL , Donahue MJ , Haploidentical bone marrow transplantation improves cerebral hemodynamics in adults with sickle cell disease American journal of hematology. 2019 Mar 05;
Perreault AA , Sprunger DM , Venters BJ , Epigenetic and transcriptional profiling of triple negative breast cancer Scientific data. 2019 Mar 05; 6 190033
Meyer CT , Wooten DJ , Paudel BB , Bauer J , Hardeman KN , Westover D , Lovly CM , Harris LA , Tyson DR , Quaranta V , Quantifying Drug Combination Synergy along Potency and Efficacy Axes Cell systems. 2019 Feb 20; 8 (2). 97-108.e16
Trujillo P , van Wouwe NC , Lin YC , Stark AJ , Petersen KJ , Kang H , Zald DH , Donahue MJ , Claassen DO , Dopamine effects on frontal cortical blood flow and motor inhibition in Parkinson’s disease Cortex; a journal devoted to the study of the nervous system and behavior. 2019 Jan 29; 115 99-111

2018

O'Brien E , Holt ME , Salay LE , Chazin WJ , Barton JK , Substrate Binding Regulates Redox Signaling in Human DNA Primase Journal of the American Chemical Society. 2018 Nov 29;
Holt ME , Salay LE , O'Brien E , Barton JK , Chazin WJ , Functional and structural similarity of human DNA primase [4Fe4S] cluster domain constructs PloS one. 2018 Dec 18; 13 (12). e0209345
Liu Q , Herring CA , Sheng Q , Ping J , Simmons AJ , Chen B , Banerjee A , Li W , Gu G , Coffey RJ , Shyr Y , Lau KS , Quantitative assessment of cell population diversity in single-cell landscapes PLoS biology. 2018 Oct 22; 16 (10). e2006687
Chen B , Herring CA , Lau KS , pyNVR: Investigating factors affecting feature selection from scRNA-seq data for lineage reconstruction Bioinformatics (Oxford, England). 2018 Nov 16;
Schulte ML , Fu A , Zhao P , Li J , Geng L , Smith ST , Kondo J , Coffey RJ , Johnson MO , Rathmell JC , Sharick JT , Skala MC , Smith JA , Berlin J , Washington MK , Nickels ML , Manning HC , Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models Nature medicine. 2018 Jan 15; 24 (2). 194-202
Oviatt AA , Kuriappan JA , Minniti E , Vann KR , Onuorah P , Minarini A , De Vivo M , Osheroff N , Polyamine-containing etoposide derivatives as poisons of human type II topoisomerases: Differential effects on topoisomerase IIα and IIβ Bioorganic & medicinal chemistry letters. 2018 Jul 05; 28 (17). 2961-2968
Cogswell PM , Siero JCW , Lants SK , Waddle S , Davis LT , Gilbert G , Hendrikse J , Donahue MJ , Variable impact of CSF flow suppression on quantitative 3.0T intracranial vessel wall measurements Journal of magnetic resonance imaging : JMRI. 2018 Mar 31; 48 (4). 1120-1128
Juttukonda MR , Lee CA , Patel NJ , Davis LT , Waddle SL , Gindville MC , Pruthi S , Kassim AA , DeBaun MR , Donahue MJ , Jordan LC , Differential cerebral hemometabolic responses to blood transfusions in adults and children with sickle cell anemia Journal of magnetic resonance imaging : JMRI. 2018 Oct 15; 49 (2). 466-477
Perry NA , Kaoud TS , Ortega OO , Kaya AI , Marcus DJ , Pleinis JM , Berndt S , Chen Q , Zhan X , Dalby KN , Lopez CF , Iverson TM , Gurevich VV , Arrestin-3 scaffolding of the JNK3 cascade suggests a mechanism for signal amplification Proceedings of the National Academy of Sciences of the United States of America. 2018 Dec 27; 116 (3). 810-815
Juttukonda MR , Franco G , Englot DJ , Lin YC , Petersen KJ , Trujillo P , Hedera P , Landman BA , Kang H , Donahue MJ , Konrad PE , Dawant BM , Claassen DO , White matter differences between essential tremor and Parkinson disease Neurology. 2018 Nov 30; 92 (1). e30-e39
Stark AJ , Smith CT , Lin YC , Petersen KJ , Trujillo P , van Wouwe NC , Kang H , Donahue MJ , Kessler RM , Zald DH , Claassen DO , Nigrostriatal and mesolimbic Dreceptor expression in Parkinson’s disease patients with compulsive re… The Journal of neuroscience : the official journal of the Society for Neuroscience. 2018 Feb 24;
Sevy AM , Panda S , Crowe JE , Meiler J , Vorobeychik Y , Integrating linear optimization with structural modeling to increase HIV neutralization breadth. PLoS computational biology. 2018 Feb ; 14 (2). e1005999
Watchmaker JM , Lipnik AJ , Fritsche MR , Baker JC , Mouli SK , Geevarghese S , Banovac F , Omary RA , Brown DB , Are prophylactic antibiotics necessary prior to transarterial chemoembolization for hepatocellular c… Journal of surgical oncology. 2018 Mar 7;
Fritsche MR , Watchmaker JM , Lipnik AJ , Baker JC , Geevarghese S , Banovac F , Omary RA , Brown DB , Outpatient Transarterial Chemoembolization of Hepatocellular Carcinoma: Review of a Same-Day Dischar… Journal of vascular and interventional radiology : JVIR. 2018 Feb 23;
Zeng D , Brown BP , Voehler MW , Cai S , Reiter NJ , NMR resonance assignments of RNase P protein from Thermotoga maritima. Biomolecular NMR assignments. 2018 Feb 15;
Paudel BB , Harris LA , Hardeman KN , Abugable AA , Hayford CE , Tyson DR , Quaranta V , A Nonquiescent “Idling” Population State in Drug-Treated, BRAF-Mutated Melanoma. Biophysical journal. 2018 Mar 27; 114 (6). 1499-1511
Sanders CR , Hutchison JM , Membrane properties that shape the evolution of membrane enzymes. Current opinion in structural biology. 2018 Mar 26; 51 80-91
Turcot V , Lu Y , Highland HM , Schurmann C , Justice AE , Fine RS , Bradfield JP , Esko T , Giri A , Graff M , Guo X , Hendricks AE , Karaderi T , Lempradl A , Locke AE , Mahajan A , Marouli E , Sivapalaratnam S , Young KL , Alfred T , Feitosa MF , Masca NGD , Manning AK , Medina-Gomez C , Mudgal P , Ng MCY , Reiner AP , Vedantam S , Willems SM , Winkler TW , Abecasis G , Aben KK , Alam DS , Alharthi SE , Allison M , Amouyel P , Asselbergs FW , Auer PL , Balkau B , Bang LE , Barroso I , Bastarache L , Benn M , Bergmann S , Bielak LF , Blüher M , Boehnke M , Boeing H , Boerwinkle E , Böger CA , Bork-Jensen J , Bots ML , Bottinger EP , Bowden DW , Brandslund I , Breen G , Brilliant MH , Broer L , Brumat M , Burt AA , Butterworth AS , Campbell PT , Cappellani S , Carey DJ , Catamo E , Caulfield MJ , Chambers JC , Chasman DI , Chen YI , Chowdhury R , Christensen C , Chu AY , Cocca M , Collins FS , Cook JP , Corley J , Corominas Galbany J , Cox AJ , Crosslin DS , Cuellar-Partida G , D'Eustacchio A , Danesh J , Davies G , Bakker PIW , Groot MCH , Mutsert R , Deary IJ , Dedoussis G , Demerath EW , Heijer M , Hollander AI , Ruijter HM , Dennis JG , Denny JC , Angelantonio E , Drenos F , Du M , Dubé MP , Dunning AM , Easton DF , Edwards TL , Ellinghaus D , Ellinor PT , Elliott P , Evangelou E , Farmaki AE , Farooqi IS , Faul JD , Fauser S , Feng S , Ferrannini E , Ferrieres J , Florez JC , Ford I , Fornage M , Franco OH , Franke A , Franks PW , Friedrich N , Frikke-Schmidt R , Galesloot TE , Gan W , Gandin I , Gasparini P , Gibson J , Giedraitis V , Gjesing AP , Gordon-Larsen P , Gorski M , Grabe HJ , Grant SFA , Grarup N , Griffiths HL , Grove ML , Gudnason V , Gustafsson S , Haessler J , Hakonarson H , Hammerschlag AR , Hansen T , Harris KM , Harris TB , Hattersley AT , Have CT , Hayward C , He L , Heard-Costa NL , Heath AC , Heid IM , Helgeland Ø , Hernesniemi J , Hewitt AW , Holmen OL , Hovingh GK , Howson JMM , Hu Y , Huang PL , Huffman JE , Ikram MA , Ingelsson E , Jackson AU , Jansson JH , Jarvik GP , Jensen GB , Jia Y , Johansson S , Jørgensen ME , Jørgensen T , Jukema JW , Kahali B , Kahn RS , Kähönen M , Kamstrup PR , Kanoni S , Kaprio J , Karaleftheri M , Kardia SLR , Karpe F , Kathiresan S , Kee F , Kiemeney LA , Kim E , Kitajima H , Komulainen P , Kooner JS , Kooperberg C , Korhonen T , Kovacs P , Kuivaniemi H , Kutalik Z , Kuulasmaa K , Kuusisto J , Laakso M , Lakka TA , Lamparter D , Lange EM , Lange LA , Langenberg C , Larson EB , Lee NR , Lehtimäki T , Lewis CE , Li H , Li J , Li-Gao R , Lin H , Lin KH , Lin LA , Lin X , Lind L , Lindström J , Linneberg A , Liu CT , Liu DJ , Liu Y , Lo KS , Lophatananon A , Lotery AJ , Loukola A , Luan J , Lubitz SA , Lyytikäinen LP , Männistö S , Marenne G , Mazul AL , McCarthy MI , McKean-Cowdin R , Medland SE , Meidtner K , Milani L , Mistry V , Mitchell P , Mohlke KL , Moilanen L , Moitry M , Montgomery GW , Mook-Kanamori DO , Moore C , Mori TA , Morris AD , Morris AP , Müller-Nurasyid M , Munroe PB , Nalls MA , Narisu N , Nelson CP , Neville M , Nielsen SF , Nikus K , Njølstad PR , Nordestgaard BG , Nyholt DR , O'Connel JR , O'Donoghue ML , Olde Loohuis LM , Ophoff RA , Owen KR , Packard CJ , Padmanabhan S , Palmer CNA , Palmer ND , Pasterkamp G , Patel AP , Pattie A , Pedersen O , Peissig PL , Peloso GM , Pennell CE , Perola M , Perry JA , Perry JRB , Pers TH , Person TN , Peters A , Petersen ERB , Peyser PA , Pirie A , Polasek O , Polderman TJ , Puolijoki H , Raitakari OT , Rasheed A , Rauramaa R , Reilly DF , Renström F , Rheinberger M , Ridker PM , Rioux JD , Rivas MA , Roberts DJ , Robertson NR , Robino A , Rolandsson O , Rudan I , Ruth KS , Saleheen D , Salomaa V , Samani NJ , Sapkota Y , Sattar N , Schoen RE , Schreiner PJ , Schulze MB , Scott RA , Segura-Lepe MP , Shah SH , Sheu WH , Sim X , Slater AJ , Small KS , Smith AV , Southam L , Spector TD , Speliotes EK , Starr JM , Stefansson K , Steinthorsdottir V , Stirrups KE , Strauch K , Stringham HM , Stumvoll M , Sun L , Surendran P , Swift AJ , Tada H , Tansey KE , Tardif JC , Taylor KD , Teumer A , Thompson DJ , Thorleifsson G , Thorsteinsdottir U , Thuesen BH , Tönjes A , Tromp G , Trompet S , Tsafantakis E , Tuomilehto J , Tybjaerg-Hansen A , Tyrer JP , Uher R , Uitterlinden AG , Uusitupa M , Laan SW , Duijn CM , Leeuwen N , van Setten J , Vanhala M , Varbo A , Varga TV , Varma R , Velez Edwards DR , Vermeulen SH , Veronesi G , Vestergaard H , Vitart V , Vogt TF , Völker U , Vuckovic D , Wagenknecht LE , Walker M , Wallentin L , Wang F , Wang CA , Wang S , Wang Y , Ware EB , Wareham NJ , Warren HR , Waterworth DM , Wessel J , White HD , Willer CJ , Wilson JG , Witte DR , Wood AR , Wu Y , Yaghootkar H , Yao J , Yao P , Yerges-Armstrong LM , Young R , Zeggini E , Zhan X , Zhang W , Zhao JH , Zhao W , Zhou W , Zondervan KT , Rotter JI , Pospisilik JA , Rivadeneira F , Borecki IB , Deloukas P , Frayling TM , Lettre G , North KE , Lindgren CM , Hirschhorn JN , Loos RJF , , , , , , , Publisher Correction: Protein-altering variants associated with body mass index implicate pathways t… Nature genetics. 2018 Mar 16;
Jiang J , Thalamuthu A , Ho JE , Mahajan A , Ek WE , Brown DA , Breit SN , Wang TJ , Gyllensten U , Chen MH , Enroth S , Januzzi JL , Lind L , Armstrong NJ , Kwok JB , Schofield PR , Wen W , Trollor JN , Johansson Å , Morris AP , Vasan RS , Sachdev PS , Mather KA , A Meta-Analysis of Genome-Wide Association Studies of Growth Differentiation Factor-15 Concentration… Frontiers in genetics. 2018 ; 9 97
Herring CA , Chen B , McKinley ET , Lau KS , Single-Cell Computational Strategies for Lineage Reconstruction in Tissue Systems. Cellular and molecular gastroenterology and hepatology. 2018 ; 5 (4). 539-548
Chaplin V , Phipps MA , Caskey CF , A random phased-array for MR-guided transcranial ultrasound neuromodulation in non-human primates. Physics in medicine and biology. 2018 Apr 18;
Petersen KJ , Reid JA , Chakravorti S , Juttukonda MR , Franco G , Trujillo P , Stark AJ , Dawant BM , Donahue MJ , Claassen DO , Structural and functional connectivity of the nondecussating dentato-rubro-thalamic tract. NeuroImage. 2018 May 4;
Kamp F , Scheidt HA , Winkler E , Basset G , Heinel H , Hutchison JM , LaPointe LM , Sanders CR , Steiner H , Huster D , Bexarotene Binds to the Amyloid Precursor Protein Transmembrane Domain, Alters Its α-Helical Confor… ACS chemical neuroscience. 2018 May 11;
Roselli C , Chaffin MD , Weng LC , Aeschbacher S , Ahlberg G , Albert CM , Almgren P , Alonso A , Anderson CD , Aragam KG , Arking DE , Barnard J , Bartz TM , Benjamin EJ , Bihlmeyer NA , Bis JC , Bloom HL , Boerwinkle E , Bottinger EB , Brody JA , Calkins H , Campbell A , Cappola TP , Carlquist J , Chasman DI , Chen LY , Chen YI , Choi EK , Choi SH , Christophersen IE , Chung MK , Cole JW , Conen D , Cook J , Crijns HJ , Cutler MJ , Damrauer SM , Daniels BR , Darbar D , Delgado G , Denny JC , Dichgans M , Dörr M , Dudink EA , Dudley SC , Esa N , Esko T , Eskola M , Fatkin D , Felix SB , Ford I , Franco OH , Geelhoed B , Grewal RP , Gudnason V , Guo X , Gupta N , Gustafsson S , Gutmann R , Hamsten A , Harris TB , Hayward C , Heckbert SR , Hernesniemi J , Hocking LJ , Hofman A , Horimoto ARVR , Huang J , Huang PL , Huffman J , Ingelsson E , Ipek EG , Ito K , Jimenez-Conde J , Johnson R , Jukema JW , Kääb S , Kähönen M , Kamatani Y , Kane JP , Kastrati A , Kathiresan S , Katschnig-Winter P , Kavousi M , Kessler T , Kietselaer BL , Kirchhof P , Kleber ME , Knight S , Krieger JE , Kubo M , Launer LJ , Laurikka J , Lehtimäki T , Leineweber K , Lemaitre RN , Li M , Lim HE , Lin HJ , Lin H , Lind L , Lindgren CM , Lokki ML , London B , Loos RJF , Low SK , Lu Y , Lyytikäinen LP , Macfarlane PW , Magnusson PK , Mahajan A , Malik R , Mansur AJ , Marcus GM , Margolin L , Margulies KB , März W , McManus DD , Melander O , Mohanty S , Montgomery JA , Morley MP , Morris AP , Müller-Nurasyid M , Natale A , Nazarian S , Neumann B , Newton-Cheh C , Niemeijer MN , Nikus K , Nilsson P , Noordam R , Oellers H , Olesen MS , Orho-Melander M , Padmanabhan S , Pak HN , Paré G , Pedersen NL , Pera J , Pereira A , Porteous D , Psaty BM , Pulit SL , Pullinger CR , Rader DJ , Refsgaard L , Ribasés M , Ridker PM , Rienstra M , Risch L , Roden DM , Rosand J , Rosenberg MA , Rost N , Rotter JI , Saba S , Sandhu RK , Schnabel RB , Schramm K , Schunkert H , Schurman C , Scott SA , Seppälä I , Shaffer C , Shah S , Shalaby AA , Shim J , Shoemaker MB , Siland JE , Sinisalo J , Sinner MF , Slowik A , Smith AV , Smith BH , Smith JG , Smith JD , Smith NL , Soliman EZ , Sotoodehnia N , Stricker BH , Sun A , Sun H , Svendsen JH , Tanaka T , Tanriverdi K , Taylor KD , Teder-Laving M , Teumer A , Thériault S , Trompet S , Tucker NR , Tveit A , Uitterlinden AG , Van Der Harst P , Van Gelder IC , Van Wagoner DR , Verweij N , Vlachopoulou E , Völker U , Wang B , Weeke PE , Weijs B , Weiss R , Weiss S , Wells QS , Wiggins KL , Wong JA , Woo D , Worrall BB , Yang PS , Yao J , Yoneda ZT , Zeller T , Zeng L , Lubitz SA , Lunetta KL , Ellinor PT , Multi-ethnic genome-wide association study for atrial fibrillation. Nature genetics. 2018 Jun 11;
Setliff I , McDonnell WJ , Raju N , Bombardi RG , Murji AA , Scheepers C , Ziki R , Mynhardt C , Shepherd BE , Mamchak AA , Garrett N , Karim SA , Mallal SA , Crowe JE , Morris L , Georgiev IS , Multi-Donor Longitudinal Antibody Repertoire Sequencing Reveals the Existence of Public Antibody Clo… Cell host & microbe. 2018 Jun 13; 23 (6). 845-854.e6
Yang PF , Phipps MA , Newton AT , Chaplin V , Gore JC , Caskey CF , Chen LM , Neuromodulation of sensory networks in monkey brain by focused ultrasound with MRI guidance and dete… Scientific reports. 2018 May 22; 8 (1). 7993
Bertron JL , Cho HP , Garcia-Barrantes PM , Panarese JD , Salovich JM , Nance KD , Engers DW , Rook JM , Blobaum AL , Niswender CM , Stauffer SR , Conn PJ , Lindsley CW , The discovery of VU0486846: steep SAR from a series of M PAMs based on a novel benzomorpholine core. Bioorganic & medicinal chemistry letters. 2018 Jul 1; 28 (12). 2175-2179
Claxton DP , Jagessar KL , Steed PR , Stein RA , Mchaourab HS , Sodium and proton coupling in the conformational cycle of a MATE antiporter from . Proceedings of the National Academy of Sciences of the United States of America. 2018 Jul 3; 115 (27). E6182-E6190
Earl DC , Ferrell PB , Leelatian N , Froese JT , Reisman BJ , Irish JM , Bachmann BO , Discovery of human cell selective effector molecules using single cell multiplexed activity metabolo… Nature communications. 2018 Dec 2; 9 (1). 39
Sung YJ , Winkler TW , de Las Fuentes L , Bentley AR , Brown MR , Kraja AT , Schwander K , Ntalla I , Guo X , Franceschini N , Lu Y , Cheng CY , Sim X , Vojinovic D , Marten J , Musani SK , Li C , Feitosa MF , Kilpeläinen TO , Richard MA , Noordam R , Aslibekyan S , Aschard H , Bartz TM , Dorajoo R , Liu Y , Manning AK , Rankinen T , Smith AV , Tajuddin SM , Tayo BO , Warren HR , Zhao W , Zhou Y , Matoba N , Sofer T , Alver M , Amini M , Boissel M , Chai JF , Chen X , Divers J , Gandin I , Gao C , Giulianini F , Goel A , Harris SE , Hartwig FP , Horimoto ARVR , Hsu FC , Jackson AU , Kähönen M , Kasturiratne A , Kühnel B , Leander K , Lee WJ , Lin KH , 'an Luan J , McKenzie CA , Meian H , Nelson CP , Rauramaa R , Schupf N , Scott RA , Sheu WHH , Stančáková A , Takeuchi F , van der Most PJ , Varga TV , Wang H , Wang Y , Ware EB , Weiss S , Wen W , Yanek LR , Zhang W , Zhao JH , Afaq S , Alfred T , Amin N , Arking D , Aung T , Barr RG , Bielak LF , Boerwinkle E , Bottinger EP , Braund PS , Brody JA , Broeckel U , Cabrera CP , Cade B , Caizheng Y , Campbell A , Canouil M , Chakravarti A , , Chauhan G , Christensen K , Cocca M , , Collins FS , Connell JM , de Mutsert R , de Silva HJ , Debette S , Dörr M , Duan Q , Eaton CB , Ehret G , Evangelou E , Faul JD , Fisher VA , Forouhi NG , Franco OH , Friedlander Y , Gao H , , Gigante B , Graff M , Gu CC , Gu D , Gupta P , Hagenaars SP , Harris TB , He J , Heikkinen S , Heng CK , Hirata M , Hofman A , Howard BV , Hunt S , Irvin MR , Jia Y , Joehanes R , Justice AE , Katsuya T , Kaufman J , Kerrison ND , Khor CC , Koh WP , Koistinen HA , Komulainen P , Kooperberg C , Krieger JE , Kubo M , Kuusisto J , Langefeld CD , Langenberg C , Launer LJ , Lehne B , Lewis CE , Li Y , , Lim SH , Lin S , Liu CT , Liu J , Liu J , Liu K , Liu Y , Loh M , Lohman KK , Long J , Louie T , Mägi R , Mahajan A , Meitinger T , Metspalu A , Milani L , Momozawa Y , Morris AP , Mosley TH , Munson P , Murray AD , Nalls MA , Nasri U , Norris JM , North K , Ogunniyi A , Padmanabhan S , Palmas WR , Palmer ND , Pankow JS , Pedersen NL , Peters A , Peyser PA , Polasek O , Raitakari OT , Renström F , Rice TK , Ridker PM , Robino A , Robinson JG , Rose LM , Rudan I , Sabanayagam C , Salako BL , Sandow K , Schmidt CO , Schreiner PJ , Scott WR , Seshadri S , Sever P , Sitlani CM , Smith JA , Snieder H , Starr JM , Strauch K , Tang H , Taylor KD , Teo YY , Tham YC , Uitterlinden AG , Waldenberger M , Wang L , Wang YX , Wei WB , Williams C , Wilson G , Wojczynski MK , Yao J , Yuan JM , Zonderman AB , Becker DM , Boehnke M , Bowden DW , Chambers JC , Chen YI , de Faire U , Deary IJ , Esko T , Farrall M , Forrester T , Franks PW , Freedman BI , Froguel P , Gasparini P , Gieger C , Horta BL , Hung YJ , Jonas JB , Kato N , Kooner JS , Laakso M , Lehtimäki T , Liang KW , Magnusson PKE , Newman AB , Oldehinkel AJ , Pereira AC , Redline S , Rettig R , Samani NJ , Scott J , Shu XO , van der Harst P , Wagenknecht LE , Wareham NJ , Watkins H , Weir DR , Wickremasinghe AR , Wu T , Zheng W , Kamatani Y , Laurie CC , Bouchard C , Cooper RS , Evans MK , Gudnason V , Kardia SLR , Kritchevsky SB , Levy D , O'Connell JR , Psaty BM , van Dam RM , Sims M , Arnett DK , Mook-Kanamori DO , Kelly TN , Fox ER , Hayward C , Fornage M , Rotimi CN , Province MA , van Duijn CM , Tai ES , Wong TY , Loos RJF , Reiner AP , Rotter JI , Zhu X , Bierut LJ , Gauderman WJ , Caulfield MJ , Elliott P , Rice K , Munroe PB , Morrison AC , Cupples LA , Rao DC , Chasman DI , A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple S… American journal of human genetics. 2018 Mar 1; 102 (3). 375-400
Mchaourab ZF , Perreault AA , Venters BJ , ChIP-seq and ChIP-exo profiling of Pol II, H2A.Z, and H3K4me3 in human K562 cells. Scientific data. 2018 Mar 6; 5 180030

2017

Mishra S , Wu SY , Fuller AW , Wang Z , Rose KL , Schey KL , Mchaourab HS , Loss of αB-crystallin function in zebrafish reveals critical roles in the development of the lens and stress resistance of the heart The Journal of biological chemistry. 2017 Nov 21; 293 (2). 740-753
Sapkota Y , Vivo I , Steinthorsdottir V , Fassbender A , Bowdler L , Buring JE , Edwards TL , Jones S , O D , Peterse D , Rexrode KM , Ridker PM , Schork AJ , Thorleifsson G , Wallace LM , , Kraft P , Morris AP , Nyholt DR , Edwards DRV , Nyegaard M , D'Hooghe T , Chasman DI , Stefansson K , Missmer SA , Montgomery GW , Analysis of potential protein-modifying variants in 9000 endometriosis patients and 150000 controls … Scientific reports. 2017 Sep 12; 7 (1). 11380
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Li B , Fooksa M , Heinze S , Meiler J , Finding the needle in the haystack: towards solving the protein-folding problem computationally. Critical reviews in biochemistry and molecular biology. 2017 Oct 4; 1-28
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Petersen K , Van Wouwe N , Stark A , Lin YC , Kang H , Trujillo-Diaz P , Kessler R , Zald D , Donahue MJ , Claassen DO , Ventral striatal network connectivity reflects reward learning and behavior in patients with Parkins… Human brain mapping. 2017 Oct 31;
Koethe JR , McDonnell W , Kennedy A , Abana CO , Pilkinton M , Setliff I , Georgiev I , Barnett L , Hager CC , Smith R , Kalams SA , Hasty A , Mallal S , Adipose Tissue is Enriched for Activated and Late-differentiated CD8+ T cells, and Shows Distinct CD… Journal of acquired immune deficiency syndromes (1999). 2017 Oct 14;
Shockley EM , Vrugt JA , Lopez CF , PyDREAM: High-dimensional parameter inference for biological models in Python. Bioinformatics (Oxford, England). 2017 Oct 4;
Juttukonda MR , Jordan LC , Gindville MC , Davis LT , Watchmaker JM , Pruthi S , Donahue MJ , Cerebral hemodynamics and pseudo-continuous arterial spin labeling considerations in adults with sic… NMR in biomedicine. 2017 Jan 4;
Chifman J , Arat S , Deng Z , Lemler E , Pino JC , Harris LA , Kochen MA , Lopez CF , Akman SA , Torti FM , Torti SV , Laubenbacher R , Activated Oncogenic Pathway Modifies Iron Network in Breast Epithelial Cells: A Dynamic Modeling Per… PLoS computational biology. 2017 Feb ; 13 (2). e1005352
Hardeman KN , Peng C , Paudel BB , Meyer CT , Luong T , Tyson DR , Young JD , Quaranta V , Fessel JP , Dependence On Glycolysis Sensitizes BRAF-mutated Melanomas For Increased Response To Targeted BRAF I… Scientific reports. 2017 Feb 16; 7 42604
O'Brien E , Holt ME , Thompson MK , Salay LE , Ehlinger AC , Chazin WJ , Barton JK , The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport. Science (New York, N.Y.). 2017 Feb 24; 355 (6327).
Norris JL , Farrow MA , Gutierrez DB , Palmer LD , Muszynski N , Sherrod SD , Pino JC , Allen JL , Spraggins JM , Lubbock AL , Jordan A , Burns W , Poland JC , Romer C , Manier ML , Nei YW , Prentice BM , Rose KL , Hill S , Van de Plas R , Tsui T , Braman NM , Keller MR , Rutherford SA , Lobdell N , Lopez CF , Lacy DB , McLean JA , Wikswo JP , Skaar EP , Caprioli RM , Integrated, High-Throughput, Multiomics Platform Enables Data-Driven Construction of Cellular Respon… Journal of proteome research. 2017 Mar 3; 16 (3). 1364-1375
Perreault AA , Benton ML , Koury MJ , Brandt SJ , Venters BJ , Epo reprograms the epigenome of erythroid cells. Experimental hematology. 2017 Apr 11;
Chaplin V , Caskey CF , Multi-focal HIFU reduces cavitation in mild-hyperthermia. Journal of therapeutic ultrasound. 2017 ; 5 12
Cao Z , Hutchison JM , Sanders CR , Bowie JU , Backbone Hydrogen Bond Strengths Can Vary Widely in Transmembrane Helices. Journal of the American Chemical Society. 2017 Jul 25;
O'Brien E , Holt ME , Thompson MK , Salay LE , Ehlinger AC , Chazin WJ , Barton JK , Response to Comments on “The [4Fe4S] cluster of human DNA primase functions as a redox switch using … Science (New York, N.Y.). 2017 Jul 21; 357 (6348).
Harris LA , Nobile MS , Pino JC , Lubbock ALR , Besozzi D , Mauri G , Cazzaniga P , Lopez CF , GPU-powered model analysis with PySB/cupSODA. Bioinformatics (Oxford, England). 2017 Jun 28;
Claassen DO , Stark AJ , Spears CA , Petersen KJ , van Wouwe NC , Kessler RM , Zald DH , Donahue MJ , Mesocorticolimbic hemodynamic response in Parkinson’s disease patients with compulsive behaviors. Movement disorders : official journal of the Movement Disorder Society. 2017 Jun 19;
Surdel MC , Horvath DJ , Lojek LJ , Fullen AR , Simpson J , Dutter BF , Salleng KJ , Ford JB , Jenkins JL , Nagarajan R , Teixeira PL , Albertolle M , Georgiev IS , Jansen ED , Sulikowski GA , Lacy DB , Dailey HA , Skaar EP , Antibacterial photosensitization through activation of coproporphyrinogen oxidase. Proceedings of the National Academy of Sciences of the United States of America. 2017 Jul 24;
Ostenson J , Robison RK , Zwart NR , Welch BE , Multi-frequency interpolation in spiral magnetic resonance fingerprinting for correction of off-reso… Magnetic resonance imaging. 2017 Jul 8;

2016

Bangaru S , Nieusma T , Kose N , Thornburg NJ , Finn JA , Kaplan BS , King HG , Singh V , Lampley RM , Sapparapu G , Cisneros A , Edwards KM , Slaughter JC , Edupuganti S , Lai L , Richt JA , Webby RJ , Ward AB , Crowe JE , Recognition of influenza H3N2 variant virus by human neutralizing antibodies. JCI insight. 2016 Jul 7; 1 (10).
Brown BL , Lopes D , Miller DA , Tawk RG , Brasiliense LB , Ringer A , Sauvageau E , Powers CJ , Arthur A , Hoit D , Snyder K , Siddiqui A , Levy E , Hopkins LN , Cuellar H , Rodriguez-Mercado R , Veznedaroglu E , Binning M , Mocco J , Aguilar-Salinas P , Boulos A , Yamamoto J , Hanel RA , The fate of cranial neuropathy after flow diversion for carotid aneurysms. Journal of neurosurgery. 2016 Apr ; 124 (4). 1107-13
Mousa JJ , Sauer MF , Sevy AM , Finn JA , Bates JT , Alvarado G , King HG , Loerinc LB , Fong RH , Doranz BJ , Correia BE , Kalyuzhniy O , Wen X , Jardetzky TS , Schief WR , Ohi MD , Meiler J , Crowe JE , Structural basis for nonneutralizing antibody competition at antigenic site II of the respiratory sy… 2016 Nov 1; 113 (44). E6849-E6858
Poorman ME , Chaplin VL , Wilkens K , Dockery MD , Giorgio TD , Grissom WA , Caskey CF , Erratum to: Open-source, small-animal magnetic resonance-guided focused ultrasound system. 2016 Oct 19; 4 (29).
Simmons AJ , Scurrah CR , McKinley ET , Herring CA , Irish JM , Washington MK , Coffey RJ , Lau KS , Impaired coordination between signaling pathways is revealed in human colorectal cancer using single… 2016 Oct 11; 9 (449).
Choby JE , Mike LA , Mashruwala AA , Dutter BF , Dunman PM , Sulikowski GA , Boyd JM , Skaar EP , A Small-Molecule Inhibitor of Iron-Sulfur Cluster Assembly Uncovers a Link between Virulence Regulat… 2016 Oct 19;
Wu SY , Zou P , Fuller AW , Mishra S , Wang Z , Schey KL , Mchaourab HS , Expression of Cataract-linked γ-crystallin Variants in Zebrafish Reveals a Proteostasis Network tha… 2016 Oct 21;
Tang D , Li J , Buck JR , Tantawy MN , Xia Y , Harp JM , Nickels ML , Meiler J , Manning HC , Evaluation of TSPO PET Ligands [(18)F]VUIIS1009A and [(18)F]VUIIS1009B: Tracers for Cancer Imaging. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging. 2016 Nov 16;
Watchmaker JM , Juttukonda MR , Davis LT , Scott AO , Faraco CC , Gindville MC , Jordan LC , Cogswell PM , Jefferson AL , Kirshner HS , Donahue MJ , Hemodynamic mechanisms underlying elevated oxygen extraction fraction (OEF) in moyamoya and sickle c… Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2016 Jan 1; 271678X16682509
Cheng F , Zhao J , Fooksa M , Zhao Z , A network-based drug repositioning infrastructure for precision cancer medicine through targeting si… Journal of the American Medical Informatics Association : JAMIA. 2016 Mar ;
Chong KM , Leelatian N , Deguire SM , Brockman AA , Earl D , Ihrie RA , Irish JM , Bachmann BO , Sulikowski GA , The use of fluorescently-tagged apoptolidins in cellular uptake and response studies. The Journal of antibiotics. 2016 Mar 9;
Garcia-Barrantes PM , Cho HP , Blobaum AL , Niswender CM , Conn PJ , Lindsley CW , Lead optimization of the VU0486321 series of mGlu1 PAMs. Part 3. Engineering plasma stability by dis… Bioorganic & medicinal chemistry letters. 2016 Apr 15; 26 (8). 1869-72
Fischer AW , Heinze S , Putnam DK , Li B , Pino JC , Xia Y , Lopez CF , Meiler J , CASP11 – An Evaluation of a Modular BCL::Fold-Based Protein Structure Prediction Pipeline. PloS one. 2016 ; 11 (4). e0152517
Harris LA , Frick PL , Garbett SP , Hardeman KN , Paudel BB , Lopez CF , Quaranta V , Tyson DR , An unbiased metric of antiproliferative drug effect in vitro. Nature methods. 2016 May 2;
Gogliotti RD , Engers DW , Garcia-Barrantes PM , Panarese JD , Gentry PR , Blobaum AL , Morrison RD , Daniels JS , Thompson AD , Jones CK , Conn PJ , Niswender CM , Lindsley CW , Hopkins CR , Discovery of 3-aminopicolinamides as metabotropic glutamate receptor subtype 4 (mGlu4) positive allo… Bioorganic & medicinal chemistry letters. 2016 Apr 19;
Mostovoy Y , Thiemicke A , Hsu TY , Brem RB , The Role of Transcription Factors at Antisense-Expressing Gene Pairs in Yeast. Genome biology and evolution. 2016 ; 8 (6). 1748-61
Finn JA , Koehler Leman J , Willis JR , Cisneros A , Crowe JE , Meiler J , Improving Loop Modeling of the Antibody Complementarity-Determining Region 3 Using Knowledge-Based R… PloS one. 2016 ; 11 (5). e0154811
Dutter BF , Mike LA , Reid PR , Chong KM , Ramos-Hunter SJ , Skaar EP , Sulikowski GA , Decoupling Activation of Heme Biosynthesis from Anaerobic Toxicity in a Molecule Active in Staphyloc… ACS chemical biology. 2016 May 20; 11 (5). 1354-61
Foster Paul , Hubbard Tyler , Campbell Ransom , Poole Jonathan , Pridmore Michael , Bell Chris , Harrison David , Spreading Activation in Emotional Memory Networks and the Cumulative Effects of Somatic Markers Brain Informatics. 2016 ;
Perreault Andrea , Venters Bryan , The ChIP-exo Method: Identifying Protein-DNA Interactions With Near Base Pair Precision. Journal of Visualized Experiments. 2016 Jul ;
Crochiere ML , Baloglu E , Klebanov B , Donovan S , Del Alamo D , Lee M , Kauffman M , Shacham S , Landesman Y , A method for quantification of exportin-1 (XPO1) occupancy by Selective Inhibitor of Nuclear Export … Oncotarget. 2016 Jan 12; 7 (2). 1863-77
Poorman ME , Chaplin VL , Wilkens K , Dockery MD , Giorgio TD , Grissom WA , Caskey CF , Open-source, small-animal magnetic resonance-guided focused ultrasound system. Journal of therapeutic ultrasound. 2016 ; 4 (1). 22
Surdel MC , Dutter BF , Sulikowski GA , Skaar EP , Bacterial Nitric Oxide Synthase Is Required for the Staphylococcus aureus Response to Heme Stress. ACS infectious diseases. 2016 Aug 12; 2 (8). 572-8
Bender BJ , Cisneros A , Duran AM , Finn JA , Fu D , Lokits AD , Mueller BK , Sangha AK , Sauer MF , Sevy AM , Sliwoski G , Sheehan JH , DiMaio F , Meiler J , Moretti R , Protocols for Molecular Modeling with Rosetta3 and RosettaScripts. Biochemistry. 2016 Aug 30; 55 (34). 4748-63
Mansouri AL , Grese LN , Rowe EL , Pino JC , Chennubhotla SC , Ramanathan A , O'Neill HM , Berthelier V , Stanley CB , Folding propensity of intrinsically disordered proteins by osmotic stress. Molecular bioSystems. 2016 Oct 18;
Ostenson J , Pujara AC , Mikheev A , Moy L , Kim SG , Melsaether AN , Jhaveri K , Adams S , Faul D , Glielmi C , Geppert C , Feiweier T , Jackson K , Cho GY , Boada FE , Sigmund EE , Voxelwise analysis of simultaneously acquired and spatially correlated 18 F-fluorodeoxyglucose (FDG)… 2016 Oct 25;
Garcia-Barrantes PM , Cho HP , Metts AM , Blobaum AL , Niswender CM , Conn PJ , Lindsley CW , Lead optimization of the VU0486321 series of mGlu1 PAMs. Part 2: SAR of alternative 3-methyl heteroc… Bioorganic & medicinal chemistry letters. 2016 Feb 1; 26 (3). 751-6

2015

Frick PL , Paudel BB , Tyson DR , Quaranta V , Quantifying heterogeneity and dynamics of clonal fitness in response to perturbation. Journal of cellular physiology. 2015 Jul ; 230 (7). 1403-12
Jefferson Angela , Liu Dandan , Gifford Katherine , Hohman Timothy , Rane Swati , Pechman Kimberly , Logan Laura , Benson Elleena , Wisniewski Kristi , Wiggins Margaret , Samuels Lauren , Pridmore Michael , Acosta Lealani , Clinician staging of mild cognitive impairment severity yields neuropsychological, neuroimaging, and… 2015 ;
Bisignano P , Burford NT , Shang Y , Marlow B , Livingston KE , Fenton AM , Rockwell K , Budenholzer L , Traynor JR , Gerritz SW , Alt A , Filizola M , Ligand-Based Discovery of a New Scaffold for Allosteric Modulation of the μ-Opioid Receptor. Journal of chemical information and modeling. 2015 Sep ; 55 (9). 1836-43
Buck JR , McKinley ET , Fu A , Abel TW , Thompson RC , Chambless L , Watchmaker JM , Harty JP , Cooper MK , Manning HC , Preclinical TSPO Ligand PET to Visualize Human Glioma Xenotransplants: A Preliminary Study. PloS one. 2015 ; 10 (10). e0141659
Sevy AM , Jacobs TM , Crowe JE , Meiler J , Design of Protein Multi-specificity Using an Independent Sequence Search Reduces the Barrier to Low … PLoS computational biology. 2015 Jul ; 11 (7). e1004300
DeGuire SM , Earl DC , Du Y , Crews BA , Jacobs AT , Ustione A , Daniel C , Chong KM , Marnett LJ , Piston DW , Bachmann BO , Sulikowski GA , Fluorescent probes of the apoptolidins and their utility in cellular localization studies. Angewandte Chemie (International ed. in English). 2015 Jan 12; 54 (3). 961-4
Gaur P , Grissom WA , Accelerated MRI thermometry by direct estimation of temperature from undersampled k-space data. Magnetic resonance in medicine. 2015 May ; 73 (5). 1914-25
Garcia-Barrantes PM , Cho HP , Niswender CM , Byers FW , Locuson CW , Blobaum AL , Xiang Z , Rook JM , Conn PJ , Lindsley CW , Development of Novel, CNS Penetrant Positive Allosteric Modulators for the Metabotropic Glutamate Re… Journal of medicinal chemistry. 2015 Oct 22; 58 (20). 7959-71
Garcia-Barrantes PM , Cho HP , Blobaum AL , Niswender CM , Conn PJ , Lindsley CW , Lead optimization of the VU0486321 series of mGlu1 PAMs. Part 1: SAR of modifications to the central… Bioorganic & medicinal chemistry letters. 2015 Nov 15; 25 (22). 5107-10
Conde-Ceide S , Martínez-Viturro CM , Alcázar J , Garcia-Barrantes PM , Lavreysen H , Mackie C , Vinson PN , Rook JM , Bridges TM , Daniels JS , Megens A , Langlois X , Drinkenburg WH , Ahnaou A , Niswender CM , Jones CK , Macdonald GJ , Steckler T , Conn PJ , Stauffer SR , Bartolomé-Nebreda JM , Lindsley CW , Discovery of VU0409551/JNJ-46778212: An mGlu5 Positive Allosteric Modulator Clinical Candidate Targe… ACS medicinal chemistry letters. 2015 Jun 11; 6 (6). 716-20
Monroe TB , Gore JC , Bruehl SP , Benningfield MM , Dietrich MS , Chen LM , Newhouse P , Fillingim R , Chodkowski B , Atalla S , Arrieta J , Damon SM , Blackford JU , Cowan RL , Sex differences in psychophysical and neurophysiological responses to pain in older adults: a cross-… Biology of sex differences. 2015 ; 6 25
Gaur P , Partanen A , Werner B , Ghanouni P , Bitton R , Butts Pauly K , Grissom WA , Correcting heat-induced chemical shift distortions in proton resonance frequency-shift thermometry. Magnetic resonance in medicine. 2015 Aug 24;
Carpenter KL , Angold A , Chen NK , Copeland WE , Gaur P , Pelphrey K , Song AW , Egger HL , Preschool anxiety disorders predict different patterns of amygdala-prefrontal connectivity at school… PloS one. 2015 ; 10 (1). e0116854
Sengupta S , Smith DS , Gifford A , Welch EB , Whole-body continuously moving table fat-water MRI with dynamic B0 shimming at 3 Tesla. Magnetic resonance in medicine. 2015 Jul 21;
Gifford A , Walker RC , Towse TF , Brian Welch E , Correlations between quantitative fat-water magnetic resonance imaging and computed tomography in hu… Journal of medical imaging (Bellingham, Wash.). 2015 Oct ; 2 (4). 046001
Gifford A , Towse TF , Walker RC , Avison MJ , Welch EB , Human brown adipose tissue depots automatically segmented by positron emission tomography/computed t… Journal of visualized experiments : JoVE. 2015 ; (96).
Simmons AJ , Banerjee A , McKinley ET , Scurrah CR , Herring CA , Gewin LS , Masuzaki R , Karp SJ , Franklin JL , Gerdes MJ , Irish JM , Coffey RJ , Lau KS , Cytometry-based single-cell analysis of intact epithelial signaling reveals MAPK activation divergen… Molecular systems biology. 2015 Oct ; 11 (10). 835
Hutchens T , Piston DW , EphA4 Receptor Forward Signaling Inhibits Glucagon Secretion From α-Cells. Diabetes. 2015 Nov ; 64 (11). 3839-51
Koteiche HA , Claxton DP , Mishra S , Stein RA , McDonald ET , Mchaourab HS , Species-Specific Structural and Functional Divergence of α-Crystallins: Zebrafish αBa- and Rodent … Biochemistry. 2015 Sep 29; 54 (38). 5949-58
Zou P , Wu SY , Koteiche HA , Mishra S , Levic DS , Knapik E , Chen W , Mchaourab HS , A conserved role of αA-crystallin in the development of the zebrafish embryonic lens. Experimental eye research. 2015 Sep ; 138 104-13
Mitchener MM , Hermanson DJ , Shockley EM , Brown HA , Lindsley CW , Reese J , Rouzer CA , Lopez CF , Marnett LJ , Competition and allostery govern substrate selectivity of cyclooxygenase-2. Proceedings of the National Academy of Sciences of the United States of America. 2015 Oct 6; 112 (40). 12366-71
Maklashina E , Rajagukguk S , Starbird CA , McDonald WH , Koganitsky A , Eisenbach M , Iverson TM , Cecchini G , Binding of the Covalent Flavin Assembly Factor to the Flavoprotein Subunit of Complex II. The Journal of biological chemistry. 2015 Dec 7;
McKinley ET , Watchmaker JM , Chakravarthy AB , Meyerhardt JA , Engelman JA , Walker RC , Washington MK , Coffey RJ , Manning HC , [(18)F]-FLT PET to predict early response to neoadjuvant therapy in KRAS wild-type rectal cancer: a … Annals of nuclear medicine. 2015 Jul ; 29 (6). 535-42

2014

Fillingim RB , Bruehl S , Dworkin RH , Dworkin SF , Loeser JD , Turk DC , Widerstrom-Noga E , Arnold L , Bennett R , Edwards RR , Freeman R , Gewandter J , Hertz S , Hochberg M , Krane E , Mantyh PW , Markman J , Neogi T , Ohrbach R , Paice JA , Porreca F , Rappaport BA , Smith SM , Smith TJ , Sullivan MD , Verne GN , Wasan AD , Wesselmann U , The ACTTION-American Pain Society Pain Taxonomy (AAPT): an evidence-based and multidimensional appro… The journal of pain : official journal of the American Pain Society. 2014 Mar ; 15 (3). 241-9
Thompson MK , Keithly ME , Goodman MC , Hammer ND , Cook PD , Jagessar KL , Harp J , Skaar EP , Armstrong RN , Structure and function of the genomically encoded fosfomycin resistance enzyme, FosB, from Staphyloc… Biochemistry. 2014 Feb 4; 53 (4). 755-65
Mashiyama ST , Malabanan MM , Akiva E , Bhosle R , Branch MC , Hillerich B , Jagessar K , Kim J , Patskovsky Y , Seidel RD , Stead M , Toro R , Vetting MW , Almo SC , Armstrong RN , Babbitt PC , Large-scale determination of sequence, structure, and function relationships in cytosolic glutathion… PLoS biology. 2014 Apr ; 12 (4). e1001843
Mike LA , Choby JE , Brinkman PR , Olive LQ , Dutter BF , Ivan SJ , Gibbs CM , Sulikowski GA , Stauff DL , Skaar EP , Two-component system cross-regulation integrates Bacillus anthracis response to heme and cell envelo… PLoS pathogens. 2014 Mar ; 10 (3). e1004044
Chang HC , Gaur P , Chou YH , Chu ML , Chen NK , Interleaved EPI based fMRI improved by multiplexed sensitivity encoding (MUSE) and simultaneous mult… PloS one. 2014 ; 9 (12). e116378
Birmingham WR , Starbird CA , Panosian TD , Nannemann DP , Iverson TM , Bachmann BO , Bioretrosynthetic construction of a didanosine biosynthetic pathway. Nature chemical biology. 2014 May ; 10 (5). 392-9
Peng D , Kim JH , Kroncke BM , Law CL , Xia Y , Droege KD , Van Horn WD , Vanoye CG , Sanders CR , Purification and structural study of the voltage-sensor domain of the human KCNQ1 potassium ion chan… Biochemistry. 2014 Apr 1; 53 (12). 2032-42
Zhai Y , Li J , Zhu Y , Xia Y , Wang W , Yu Y , Yao K , A nonsense mutation of γD-crystallin associated with congenital nuclear and posterior polar catarac… International journal of medical sciences. 2014 ; 11 (2). 158-63
Cho HP , Garcia-Barrantes PM , Brogan JT , Hopkins CR , Niswender CM , Rodriguez AL , Venable DF , Morrison RD , Bubser M , Daniels JS , Jones CK , Conn PJ , Lindsley CW , Chemical modulation of mutant mGlu1 receptors derived from deleterious GRM1 mutations found in schiz… ACS chemical biology. 2014 Oct 17; 9 (10). 2334-46
Kazmier K , Sharma S , Quick M , Islam SM , Roux B , Weinstein H , Javitch JA , McHaourab HS , Conformational dynamics of ligand-dependent alternating access in LeuT. Nature structural & molecular biology. 2014 May ; 21 (5). 472-9
Mishra S , Verhalen B , Stein RA , Wen PC , Tajkhorshid E , Mchaourab HS , Conformational dynamics of the nucleotide binding domains and the power stroke of a heterodimeric AB… eLife. 2014 ; 3 e02740
Gentry PR , Kokubo M , Bridges TM , Noetzel MJ , Cho HP , Lamsal A , Smith E , Chase P , Hodder PS , Niswender CM , Daniels JS , Conn PJ , Lindsley CW , Wood MR , Development of a Highly Potent, Novel M5 Positive Allosteric Modulator (PAM) Demonstrating CNS Expos… Journal of medicinal chemistry. 2014 Sep 3;
Gentry PR , Kokubo M , Bridges TM , Cho HP , Smith E , Chase P , Hodder PS , Utley TJ , Rajapakse A , Byers F , Niswender CM , Morrison RD , Daniels JS , Wood MR , Conn PJ , Lindsley CW , Discovery, synthesis and characterization of a highly muscarinic acetylcholine receptor (mAChR)-sele… ChemMedChem. 2014 Aug ; 9 (8). 1677-82
Foster DJ , Gentry PR , Lizardi-Ortiz JE , Bridges TM , Wood MR , Niswender CM , Sulzer D , Lindsley CW , Xiang Z , Conn PJ , M5 receptor activation produces opposing physiological outcomes in dopamine neurons depending on the… The Journal of neuroscience : the official journal of the Society for Neuroscience. 2014 Feb 26; 34 (9). 3253-62
Wenthur CJ , Gentry PR , Mathews TP , Lindsley CW , Drugs for allosteric sites on receptors. Annual review of pharmacology and toxicology. 2014 ; 54 165-84

2013

Friberg A , Vigil D , Zhao B , Daniels RN , Burke JP , Garcia-Barrantes PM , Camper D , Chauder BA , Lee T , Olejniczak ET , Fesik SW , Discovery of potent myeloid cell leukemia 1 (Mcl-1) inhibitors using fragment-based methods and stru… Journal of medicinal chemistry. 2013 Jan 10; 56 (1). 15-30
Damo SM , Kehl-Fie TE , Sugitani N , Holt ME , Rathi S , Murphy WJ , Zhang Y , Betz C , Hench L , Fritz G , Skaar EP , Chazin WJ , Molecular basis for manganese sequestration by calprotectin and roles in the innate immune response … Proceedings of the National Academy of Sciences of the United States of America. 2013 Mar 5; 110 (10). 3841-6
Thompson MK , Keithly ME , Harp J , Cook PD , Jagessar KL , Sulikowski GA , Armstrong RN , Structural and chemical aspects of resistance to the antibiotic fosfomycin conferred by FosB from Ba… Biochemistry. 2013 Oct 15; 52 (41). 7350-62
Mike LA , Dutter BF , Stauff DL , Moore JL , Vitko NP , Aranmolate O , Kehl-Fie TE , Sullivan S , Reid PR , DuBois JL , Richardson AR , Caprioli RM , Sulikowski GA , Skaar EP , Activation of heme biosynthesis by a small molecule that is toxic to fermenting Staphylococcus aureu… Proceedings of the National Academy of Sciences of the United States of America. 2013 May 14; 110 (20). 8206-11
Gentry PR , Kokubo M , Bridges TM , Kett NR , Harp JM , Cho HP , Smith E , Chase P , Hodder PS , Niswender CM , Daniels JS , Conn PJ , Wood MR , Lindsley CW , Discovery of the first M5-selective and CNS penetrant negative allosteric modulator (NAM) of a musca… Journal of medicinal chemistry. 2013 Nov 27; 56 (22). 9351-5

2012

Mishra S , Stein RA , McHaourab HS , Cataract-linked γD-crystallin mutants have weak affinity to lens chaperones α-crystallins. FEBS letters. 2012 Feb 17; 586 (4). 330-6