Research & Publications


Dean Balser's research program has been aimed at the pharmacogenomics of cardiac arrhythmias. His studies in Nature, PNAS, and Nature Structural and Molecular Biology have established new paradigms for cardiac excitation-contraction coupling, and are yielding new targets for arrhythmia control.


Petersen CI, McFarland TR, Stepanovic SZ, Yang P, Reiner DJ, Hayashi K, George AL, Roden DM, Thomas JH, Balser JR. In vivo identification of genes that modify ether-a-go-go related gene activity in Caenorhabditis elegans may also affect human cardiac arrhythmia. Proceedings of the National Academy of Sciences (USA). 101: 11773-11778, 2004.

Tan HL, Kupershmidt S, Zhang R, Stepanovic S, Roden DM, Wilde AA, Anderson ME, Balser JR. A calcium sensor in the sodium channel modulates cardiac excitability. Nature. 2002 Jan 24;415(6870):442-7.

Schwinn DA, Balser JR. Anesthesiology physician scientists in academic medicine: a wake-up call. Anesthesiology. 2006 Jan;104(1):170-8. Review.

Wingo TL, Shah VN, Anderson ME, Lybrand TP, Chazin WJ, Balser JR. An EF-hand in the sodium channel couples intracellular calcium to cardiac excitability. Nat Struct Mol Biol. 2004 Mar;11(3):219-25.

Baruchin A, Balser JR: Science at the Interstices: An Evolution in the Academy. Academic Medicine; 83(9):827-31, 2008.

See all of Dean Balser's publications.