Amos M. Sakwe
Associate Professor of Biochemistry and Cancer Biology, Meharry Medical College
My laboratory studies the role of the Ca2+ dependent membrane binding Annexin A6 in triple negative breast cancer progression and chemo-resistance. Our interest in EV Research is based on our previous studies and recent findings that Annxexin A6 is enriched in extracellular vesicles and that AnxA6 containing EVs promote both pancreatic and breast cancer metastasis. We are therefore, interested in understanding in greater detail, the role of Annexin A6 containing EVs in TNBC progression and chemo-resistance.