James G. Patton
Stevenson Professor and Chair, Department of Biological Sciences, Vanderbilt University
Professor of Cell & Developmental Biology
Professor of Ophthalmology & Visual Sciences
My laboratory studies EVs in colorectal cancer and retina regeneration, focusing on miRNA transfer between cells.
Increasingly detailed analysis of vertebrate genomes has shown that the majority of the genome is transcribed into RNA but only a small fraction of the total RNA codes for protein. A much larger fraction consists of noncoding RNAs, both large and small. Broadly, we seek to understand the role that small noncoding RNAs play during vertebrate development focusing mostly on microRNAs (miRNAs).