Open Positions

Check for any staff scientist openings at http://www.vanderbilt.edu/work-at-vanderbilt/, search word: Fesik

POSTDOCTORAL RESEARCH FELLOWS IN STRUCTURAL BIOLOGY

The Fesik lab is a multi-disciplinary group in the Department of Biochemistry at Vanderbilt University, dedicated to oncology drug discovery.  We have an exciting opportunity for a talented and motivated structural biologist to join this dynamic group.  This individual will work closely with cell biologists and chemists and will clone, express and purify recombinant proteins, carry out fragment-based screen by NMR, co-crystallize target proteins with small-molecule inhibitors, interpret Structure Activity Relationships (SAR), and contribute to the discovery of new targets for cancer drug discovery.

If interested, please provide a cover letter describing your relevant experience, a curriculum vitae, and a short research summary of your work to stephen.fesik@vanderbilt.edu.

POSTDOCTORAL RESEARCH FELLOWS IN MEDICINAL CHEMISTRY

The Fesik Lab at Vanderbilt University has immediate openings for talented and accomplished synthetic chemists to join our group as postdoctoral research fellows and engage in groundbreaking cancer research.

The Fesik Lab is comprised of multi-disciplinary project teams, each with structural biologists, medicinal chemists, and cell/cancer biologists, committed to discovering and developing novel therapeutics for the treatment of cancer. We use fragment-based screening and structure-based design to discover small molecule inhibitors for important oncology targets.

Postdoctoral chemists in our group have the opportunity to learn and apply cutting edge approaches to drug design and synthesize analogs of hit molecules to improve binding affinity to a protein target and activity in cancer cells and then to optimize the pharmaceutical properties of these molecules. The close collaborations between synthetic chemists and cancer biologists, structural biologists, and pharmacologists in our group will provide excellent training in medicinal chemistry and drug discovery.

The ideal candidates will have a Ph.D. in synthetic organic chemistry with extensive training in synthetic methodology and/or total synthesis. Experience in parallel synthesis and compound library generation is a plus. If interested, please provide a cover letter describing your relevant experience, a curriculum vitae, and a short research summary of your work to stephen.fesik@vanderbilt.edu.