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Holly Algood

Vanderbilt Digestive Diseases Research Center (VDDRC)
Vanderbilt-Ingram Cancer Center (VICC)
Vanderbilt Center for Mucosal Inflammation and Cancer (CMIC)
Vanderbilt Institute for Infection, Immunology and Inflammation (VI4)
Department of Pathology, Microbiology and Immunology (PMI)
Department of Medicine
Division of Infectious Diseases


Projects in Dr. Algood’s lab focus on pathogen – host interactions in chronic infections and during chronic inflammation. Her projects investigate how T cell cytokines influence gastric epithelial cells responding to infection but also even more broadly how T cell cytokines activate other cells to protect the epithelial cells and the mucosal barrier they maintain. The main model system the laboratory uses to address these processes is H. pylori, but she is interested in many processes in mucosal immunology.

Projects in Dr. Algood’s lab focus on pathogen – host interactions in chronic infections and during chronic inflammation. Her projects investigate how T cell cytokines influence gastric epithelial cells responding to infection but also even more broadly how T cell cytokines activate other cells to protect the epithelial cells and the mucosal barrier they maintain. The main model system the laboratory uses to address these processes is H. pylori, but she is interested in many processes in mucosal immunology.

Keywords: Host-pathogen interactions , Mucosal Immunology , T lymphocyte responses , inflammation , gastric cancer

Research Area: Host-Pathogen Interactions , Epithelial Biology , Bacteriology , Immunology , Cancer Biology , Cancer Immunology