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Kathryn Brewer

University of Kansas

Chuck Sanders lab

I’m studying the human potassium channel KCNQ1, defects in which cause a number of heart arrhythmias. In particular, I’m studying the voltage sensing domain of the channel. I hope to elucidate a structure for the closed state of this domain, which will provide new insight into channel function. I am also working on improving energy calculations for KCNQ1 mutants to assist in the development of tools for mutation severity prediction.