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Mariana Jimenez

University of Michigan

Todd Graham Lab

Our lab’s goal is to determine how biological membranes are assembled and organized. One of the main focuses in the lab are the P4-ATPases, or flippases, which work to produce asymmetric membranes by flipping phospholipids from the extracellular/luminal leaflet to the cytosolic leaflet. My project is focused on identifying trafficking pathways required for proper localization and function of the flippases implicated in neurological diseases.