Shane Hutson
Department of Physics and Astronomy
Department of Biological Sciences
Vanderbilt Institute for Integrative Biosystems Research and Education (VIIBRE)
Vanderbilt-Pittsburgh Resource for Organotypic Models for Predictive Toxicology (VPROMPT)
The Hutson lab is interested in understanding the cell-level forces that drive epithelial morphogenesis and wound healing. Current projects include the following: measurement of cellular forces in vivo — both via laser manipulations and image-based force inference; understanding how these forces are perturbed after exposure to chemicals with developmental toxicity; and investigations of the calcium signaling pathways by which cells detect and respond to wounds. Projects include both experimental and computational approaches.
The Hutson lab is interested in understanding the cell-level forces that drive epithelial morphogenesis and wound healing. Current projects include the following: measurement of cellular forces in vivo — both via laser manipulations and image-based force inference; understanding how these forces are perturbed after exposure to chemicals with developmental toxicity; and investigations of the calcium signaling pathways by which cells detect and respond to wounds. Projects include both experimental and computational approaches.
Keywords: morphogenesis , mechanics , computational modeling , laser ablation , toxicology , Drosophila
Research Area: Biophysics , Computational and Systems Biology , Epithelial Biology , Cell Signaling