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MALDI Imaging Mass Spectrometry Spatially Maps Age-Related Deamidation and Truncation of Human Lens Aquaporin-0.


AUTHORS

Wenke| Rose| Spraggins| Schey JL| KL| JM| KL , . Investigative ophthalmology & visual science. 2015 11 1; 56(12). 7398-405

ABSTRACT

To spatially map human lens Aquaporin-0 (AQP0) protein modifications, including lipidation, truncation, and deamidation, from birth through middle age using matrix-assisted laser desorption ionization (MALDI) imaging mass spectrometry (IMS).



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