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National Research Resource for Imaging Mass Spectrometry


2021

Bisht K , Moore JL , Caprioli RM , Skaar EP , Wakeman CA , Impact of temperature-dependent phage expression on Pseudomonas aeruginosa biofilm formation NPJ biofilms and microbiomes. 2021 Mar 16; 7 (1). 22

2020

McMillen JC , Fincher JA , Klein DR , Spraggins JM , Caprioli RM , Effect of MALDI matrices on lipid analyses of biological tissues using MALDI-2 postionization mass spectrometry Journal of mass spectrometry : JMS. 2020 Dec 4; 55 (12). e4663
Prentice BM , Ryan DJ , Grove KJ , Cornett DS , Caprioli RM , Spraggins JM , Dynamic Range Expansion by Gas-Phase Ion Fractionation and Enrichment for Imaging Mass Spectrometry Analytical chemistry. 2020 Sep 9; 92 (19). 13092-13100
Limbrick EM , Yñigez-Gutierrez AE , Dulin CC , Derewacz DK , Spraggins JM , McCulloch KM , Iverson TM , Bachmann BO , Methyltransferase Contingencies in the Pathway of Everninomicin D Antibiotics and Analogues Chembiochem : a European journal of chemical biology. 2020 Sep 7; 21 (23). 3349-3358
Manzo T , Prentice BM , Anderson KG , Raman A , Schalck A , Codreanu GS , Nava Lauson CB , Tiberti S , Raimondi A , Jones MA , Reyzer M , Bates BM , Spraggins JM , Patterson NH , McLean JA , Rai K , Tacchetti C , Tucci S , Wargo JA , Rodighiero S , Clise-Dwyer K , Sherrod SD , Kim M , Navin NE , Caprioli RM , Greenberg PD , Draetta G , Nezi L , Accumulation of long-chain fatty acids in the tumor microenvironment drives dysfunction in intrapancreatic CD8+ T cells The Journal of experimental medicine. 2020 Aug 3; 217 (8).
Zhang L , Yang C , Pfeifer JD , Caprioli RM , Judd AM , Patterson NH , Reyzer ML , Norris JL , Maluf HM , Histopathologic, immunophenotypic, and proteomics characteristics of low-grade phyllodes tumor and fibroadenoma: more similarities than differences NPJ breast cancer. 2020 Jun 26; 6 (1). 27
Verbeeck N , Caprioli RM , Van de Plas R , Unsupervised machine learning for exploratory data analysis in imaging mass spectrometry Mass spectrometry reviews. 2020 May 11; 39 (3). 245-291
Jones MA , Cho SH , Patterson NH , Van de Plas R , Spraggins JM , Boothby MR , Caprioli RM , Discovering New Lipidomic Features Using Cell Type Specific Fluorophore Expression to Provide Spatial and Biological Specificity in a Multimodal Workflow with MALDI Imaging Mass Spectrometry Analytical chemistry. 2020 May 6; 92 (10). 7079-7086
Anderson DM , Nye-Wood MG , Rose KL , Donaldson PJ , Grey AC , Schey KL , MALDI imaging mass spectrometry of β- and γ-crystallins in the ocular lens Journal of mass spectrometry : JMS. 2020 Apr 5; 55 (4). e4473
Laut CL , Perry WJ , Metzger AL , Weiss A , Stauff DL , Walker S , Caprioli RM , Skaar EP , Bacillus anthracis Responds to Targocil-Induced Envelope Damage through EdsRS Activation of Cardiolipin Synthesis mBio. 2020 Mar 31; 11 (2).
Perry WJ , Weiss A , Van de Plas R , Spraggins JM , Caprioli RM , Skaar EP , Integrated molecular imaging technologies for investigation of metals in biological systems: A brief review Current opinion in chemical biology. 2020 Feb 19; 55 127-135
Perry WJ , Patterson NH , Prentice BM , Neumann EK , Caprioli RM , Spraggins JM , Uncovering matrix effects on lipid analyses in MALDI imaging mass spectrometry experiments Journal of mass spectrometry : JMS. 2020 Feb 11; 55 (4). e4491

2019

Spraggins JM , Djambazova KV , Rivera ES , Migas LG , Neumann EK , Fuetterer A , Suetering J , Goedecke N , Ly A , Van de Plas R , Caprioli RM , High-Performance Molecular Imaging with MALDI Trapped Ion-Mobility Time-of-Flight (timsTOF) Mass Spectrometry Analytical chemistry. 2019 Oct 28; 91 (22). 14552-14560
Dufresne M , Patterson NH , Norris JL , Caprioli RM , Combining Salt Doping and Matrix Sublimation for High Spatial Resolution MALDI Imaging Mass Spectrometry of Neutral Lipids Analytical chemistry. 2019 Oct 15; 91 (20). 12928-12934
Perry WJ , Spraggins JM , Sheldon JR , Grunenwald CM , Heinrichs DE , Cassat JE , Skaar EP , Caprioli RM , Staphylococcus aureus exhibits heterogeneous siderophore production within the vertebrate host Proceedings of the National Academy of Sciences of the United States of America. 2019 Oct 14; 116 (44). 21980-21982
Yang B , Tsui T , Caprioli RM , Norris JL , Sample Preparation and Analysis of Single Cells Using High Performance MALDI FTICR Mass Spectrometry Methods in molecular biology (Clifton, N.J.). 2019 Sep 30; 2064 125-134
Judd AM , Gutierrez DB , Moore JL , Patterson NH , Yang J , Romer CE , Norris JL , Caprioli RM , A recommended and verified procedure for in situ tryptic digestion of formalin-fixed paraffin-embedded tissues for analysis by matrix-assisted laser desorption/ionization imaging mass spectrometry Journal of mass spectrometry : JMS. 2019 Aug 1; 54 (8). 716-727
Gessel MM , Spraggins JM , Voziyan PA , Abrahamson DR , Caprioli RM , Hudson BG , Two Specific Sulfatide Species Are Dysregulated during Renal Development in a Mouse Model of Alport Syndrome Lipids. 2019 Jun 13; 54 (6-7). 411-418
Ryan DJ , Patterson NH , Putnam NE , Wilde AD , Weiss A , Perry WJ , Cassat JE , Skaar EP , Caprioli RM , Spraggins JM , MicroLESA: Integrating Autofluorescence Microscopy, In Situ Micro-Digestions, and Liquid Extraction Surface Analysis for High Spatial Resolution Targeted Proteomic Studies Analytical chemistry. 2019 May 31; 91 (12). 7578-7585
Prentice BM , Hart NJ , Phillips N , Haliyur R , Judd A , Armandala R , Spraggins JM , Lowe CL , Boyd KL , Stein RW , Wright CV , Norris JL , Powers AC , Brissova M , Caprioli RM , Imaging mass spectrometry enables molecular profiling of mouse and human pancreatic tissue Diabetologia. 2019 Apr 6; 62 (6). 1036-1047
Spraggins M. , Schwamborn Kristina , Heeren M. A. , Eberlin S. , The Importance of Clinical Tissue Imaging Clinical Mass Spectrometry. 2019 Apr 1; (12). 47-49
Spivey EC , McMillen JC , Ryan DJ , Spraggins JM , Caprioli RM , Combining MALDI-2 and transmission geometry laser optics to achieve high sensitivity for ultra-high spatial resolution surface analysis Journal of mass spectrometry : JMS. 2019 Apr 1; 54 (4). 366-370
Ryan DJ , Spraggins JM , Caprioli RM , Protein identification strategies in MALDI imaging mass spectrometry: a brief review Current opinion in chemical biology. 2019 Feb 4; 48 64-72
Schwamborn K , Weirich G , Steiger K , Zimmermann G , Schmidmayr M , Weichert W , Caprioli RM , Discerning the Primary Carcinoma in Malignant Peritoneal and Pleural Effusions Using Imaging Mass Spectrometry-A Feasibility Study Proteomics. Clinical applications. 2019 Jan 12; 13 (1). e1800064
Linder JE , Batey K , Johnston R , Cohen EM , Wang Y , Wang X , Zaleski NM , Rogers LM , McDonald WH , Reyzer ML , Judd A , Goldstein J , Correa H , Pulley J , Aronoff DM , The PathLink Acquired Gestational Tissue Bank: Feasibility of Project PLACENTA Journal of reproductive biotechnology & fertility. 2019 Jan 9; 7 14-27

2018

Knippel RJ , Zackular JP , Moore JL , Celis AI , Weiss A , Washington MK , DuBois JL , Caprioli RM , Skaar EP , Heme sensing and detoxification by HatRT contributes to pathogenesis during Clostridium difficile infection PLoS pathogens. 2018 Dec 21; 14 (12). e1007486
Patterson NH , Tuck M , Lewis A , Kaushansky A , Norris JL , Van de Plas R , Caprioli RM , Next Generation Histology-Directed Imaging Mass Spectrometry Driven by Autofluorescence Microscopy Analytical chemistry. 2018 Oct 16;
Patterson NH , Tuck M , Van de Plas R , Caprioli RM , Advanced Registration and Analysis of MALDI Imaging Mass Spectrometry Measurements through Autofluorescence Microscopy Analytical chemistry. 2018 Oct 16;
Noble KV , Reyzer ML , Barth JL , McDonald H , Tuck M , Schey KL , Krug EL , Lang H , Use of Proteomic Imaging Coupled With Transcriptomic Analysis to Identify Biomolecules Responsive to Cochlear Injury Frontiers in molecular neuroscience. 2018 Jul 17; 11 243
Yang J , Norris JL , Caprioli R , Novel vacuum stable ketone-based matrices for high spatial resolution MALDI imaging mass spectrometry Journal of mass spectrometry : JMS. 2018 Aug 21; 53 (10). 1005-1012
Cressman ENK , Spraggins JM , Viewing the Future of IR through Molecular Histology: An Overview of Imaging Mass Spectrometry Journal of vascular and interventional radiology : JVIR. 2018 Sep 28; 29 (11). 1543-1546.e1
Covington BC , Spraggins JM , Ynigez-Gutierrez AE , Hylton ZB , Bachmann BO , Response of Secondary Metabolism of Hypogean Actinobacterial Genera to Chemical and Biological Stimuli Applied and environmental microbiology. 2018 Sep 17; 84 (19).
Kleinridders| Ferris| Reyzer| Rath| Soto| Manier| Spraggins| Yang| Stanton| Caprioli| Kahn A| HA| ML| M| M| ML| J| Z| RC| RM| CR , Regional differences in brain glucose metabolism determined by imaging mass spectrometry. Molecular metabolism. 2018 Jun ; 12 113-121
Grove| Lareau| Voziyan| Zeng| Harris| Hudson| Caprioli KJ| NM| PA| F| RC| BG| RM , Imaging mass spectrometry reveals direct albumin fragmentation within the diabetic kidney. Kidney international. 2018 May 17;
Yang| Patterson| Tsui| Caprioli| Norris B| NH| T| RM| JL , Single-Cell Mass Spectrometry Reveals Changes in Lipid and Metabolite Expression in RAW 264.7 Cells … Journal of the American Society for Mass Spectrometry. 2018 May ; 29 (5). 1012-1020
Prentice| Ryan| Van de Plas| Caprioli| Spraggins BM| DJ| R| RM| JM , Enhanced Ion Transmission Efficiency up to m/ z 24 000 for MALDI Protein Imaging Mass Spectrometry… Analytical chemistry. 2018 Apr 17; 90 (8). 5090-5099
Ryan| Nei| Prentice| Rose| Caprioli| Spraggins DJ| D| BM| KL| RM| JM , Protein identification in imaging mass spectrometry through spatially targeted liquid micro-extracti… Rapid communications in mass spectrometry : RCM. 2018 Mar 15; 32 (5). 442-450
Cassat| Moore| Wilson| Stark| Prentice| Van de Plas| Perry| Zhang| Virostko| Colvin| Rose| Judd| Reyzer| Spraggins| Grunenwald| Gore| Caprioli| Skaar JE| JL| KJ| Z| BM| R| WJ| Y| J| DC| KL| AM| ML| JM| CM| JC| RM| EP , Integrated molecular imaging reveals tissue heterogeneity driving host-pathogen interactions. Science translational medicine. 2018 Mar 14; 10 (432).
Soto| Orliaguet| Reyzer| Manier| Caprioli| Kahn M| L| ML| ML| RM| CR , Pyruvate induces torpor in obese mice. Proceedings of the National Academy of Sciences of the United States of America. 2018 Dec 23; 115 (4). 810-815
Stark| Anderson| Kwong| Patterson| Schey| Caprioli| Caprioli DT| DMG| JMK| NH| KL| RM| J , Optic Nerve Regeneration After Crush Remodels the Injury Site: Molecular Insights From Imaging Mass … Investigative ophthalmology & visual science. 2018 Jan 1; 59 (1). 212-222
Prentice BM , McMillen JC , Caprioli RM , Multiple TOF/TOF Events in a Single Laser Shot for Multiplexed Lipid Identifications in MALDI Imaging Mass Spectrometry International journal of mass spectrometry. 2018 Jun 28; 437 30-37
Richmond Anne , Lindsley W. , Daniels B. , Froehler T. , Reyzer L. , Pharmacokinetics, Tissue Localization, Toxicity, and Treatment Efficacy in the First Small Animal (Rabbit) Model of Intra-Arterial Chemotherapy for Retinoblastoma Investigative Ophthalmology & Visual Science. 2018 Jan 4; 1 (59). 446-454

2017

Juttukonda| Berends| Zackular| Moore| Stier| Zhang| Schmitz| Beavers| Wijers| Gilston| Kehl-Fie| Atkinson| Washington| Peebles| Chazin| Torres| Caprioli| Skaar LJ| ETM| JP| JL| MT| Y| JE| WN| CD| BA| TE| J| MK| RS| WJ| VJ| RM| EP , Dietary Manganese Promotes Staphylococcal Infection of the Heart. Cell host & microbe. 2017 Oct 11; 22 (4). 531-542.e8
Prentice| Chumbley| Caprioli BM| CW| RM , Absolute Quantification of Rifampicin by MALDI Imaging Mass Spectrometry Using Multiple TOF/TOF Even… Journal of the American Society for Mass Spectrometry. 2017 Jan ; 28 (1). 136-144
Anderson| Lambert| Calkins| Ablonczy| Crouch| Caprioli| Schey DMG| W| DJ| Z| RK| RM| KL , Imaging MS of Rodent Ocular Tissues and the Optic Nerve. Methods in molecular biology (Clifton, N.J.). 2017 ; 1618 15-27
Lazova| Yang| El Habr| Lim| Choate| Seeley| Caprioli| Yangqun R| Z| C| Y| KA| EH| RM| L , Mass Spectrometry Imaging Can Distinguish on a Proteomic Level Between Proliferative Nodules Within … The American Journal of dermatopathology. 2017 Sep ; 39 (9). 689-695
Rizzo| Prentice| Moore| Norris| Caprioli DG| BM| JL| JL| RM , Enhanced Spatially Resolved Proteomics Using On-Tissue Hydrogel-Mediated Protein Digestion. Analytical chemistry. 2017 Mar 7; 89 (5). 2948-2955
Verbeeck| Spraggins| Murphy| Wang| Deutch| Caprioli| Van de Plas N| JM| MJM| HD| AY| RM| R , Connecting imaging mass spectrometry and magnetic resonance imaging-based anatomical atlases for aut… Biochimica et biophysica acta. 2017 Dec ; 1865 (7). 967-977
Prentice| Caprioli| Vuiblet BM| RM| V , Label-free molecular imaging of the kidney. Kidney international. 2017 Sep ; 92 (3). 580-598
Nye-Wood| Spraggins| Caprioli| Schey| Donaldson| Grey MG| JM| RM| KL| PJ| AC , Spatial distributions of glutathione and its endogenous conjugates in normal bovine lens and a model… Experimental eye research. 2017 Jan ; 154 70-78
Anderson| Ablonczy| Koutalos| Hanneken| Spraggins| Calcutt| Crouch| Caprioli| Schey DMG| Z| Y| AM| JM| MW| RK| RM| KL , Bis(monoacylglycero)phosphate lipids in the retinal pigment epithelium implicate lysosomal/endosomal… Scientific reports. 2017 Dec 11; 7 (1). 17352
Angel PM , Baldwin HS , Gottlieb Sen D , Su YR , Mayer JE , Bichell D , Drake RR , Advances in MALDI imaging mass spectrometry of proteins in cardiac tissue, including the heart valve Biochimica et biophysica acta. Proteins and proteomics. 2017 Mar 21; 1865 (7). 927-935

2016

Norris| Tsui| Gutierrez| Caprioli JL| T| DB| RM , Pathology interface for the molecular analysis of tissue by mass spectrometry. Journal of pathology informatics. 2016 ; 7 13
Angel| Bayoumi| Hinton| Ru Su| Bichell| Mayer| Scott Baldwin| Caprioli PM| AS| RB| Y| D| JE| H| RM , MALDI Imaging Mass Spectrometry as a Lipidomic Approach to Heart Valve Research. The Journal of heart valve disease. 2016 Mar ; 25 (2). 240-252
Chumbley| Reyzer| Allen| Marriner| Via| Barry 3rd| Caprioli CW| ML| JL| GA| LE| CE| RM , Absolute Quantitative MALDI Imaging Mass Spectrometry: A Case of Rifampicin in Liver Tissues. Analytical chemistry. 2016 Jan 26;
Anderson| Van de Plas| Rose| Hill| Schey| Solga| Gutmann| Caprioli DM| R| KL| S| KL| AC| DH| RM , 3-D imaging mass spectrometry of protein distributions in mouse Neurofibromatosis 1 (NF1)-associated… Journal of proteomics. 2016 Feb 12;
Spraggins| Rizzo| Moore| Noto| Skaar| Caprioli JM| DG| JL| MJ| EP| RM , Next-generation technologies for spatial proteomics: Integrating ultra-high speed MALDI-TOF and high… Proteomics. 2016 Jun ; 16 (11-12). 1678-89
Wakeman| Moore| Noto| Zhang| Singleton| Prentice| Gilston| Doster| Gaddy| Chazin| Caprioli| Skaar CA| JL| MJ| Y| MD| BM| BA| RS| JA| WJ| RM| EP , The innate immune protein calprotectin promotes Pseudomonas aeruginosa and Staphylococcus aureus int… Nature communications. 2016 ; 7 11951
Prentice| Caprioli BM| RM , The Need for Speed in Matrix-Assisted Laser Desorption/Ionization Imaging Mass Spectrometry Journal of Postdoctoral Research. 2016 ; 4 (3). 3-13
Zubair| Prentice| Norris| Laibinis| Caprioli F| BM| JL| PE| RM , A Standard Reticle Slide to Objectively Evaluate Spatial Resolution and Instrument Performance in Im… Analytical chemistry. 2016 Jun 14;
Taverna| Pollins| Sindona| Caprioli| Nanney D| AC| G| RM| LB , Imaging mass spectrometry for accessing molecular changes during burn wound healing. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. 2016 Jun 3;
Caprioli RM , Imaging mass spectrometry: Molecular microscopy for the new age of biology and medicine. Proteomics. 2016 Jun ; 16 (11-12). 1607-12
Taverna| Pollins| Nanney| Sindona| Caprioli D| AC| LB| G| RM , Histology-guided protein digestion/extraction from formalin-fixed and paraffin-embedded pressure ulc… Experimental dermatology. 2016 Feb ; 25 (2). 143-6
Zubair F , Laibinis PE , Swisher WG , Yang J , Spraggins JM , Norris JL , Caprioli RM , Trypsin and MALDI matrix pre-coated targets simplify sample preparation for mapping proteomic distributions within biological tissues by imaging mass spectrometry Journal of mass spectrometry : JMS. 2016 Dec 3; 51 (12). 1168-1179
Zackular JP , Moore JL , Jordan AT , Juttukonda LJ , Noto MJ , Nicholson MR , Crews JD , Semler MW , Zhang Y , Ware LB , Washington MK , Chazin WJ , Caprioli RM , Skaar EP , Dietary zinc alters the microbiota and decreases resistance to Clostridium difficile infection Nature medicine. 2016 Sep 26; 22 (11). 1330-1334
Prentice BM , Chumbley CW , Hachey BC , Norris JL , Caprioli RM , Multiple Time-of-Flight/Time-of-Flight Events in a Single Laser Shot for Improved Matrix-Assisted Laser Desorption/Ionization Tandem Mass Spectrometry Quantification Analytical chemistry. 2016 Sep 14; 88 (19). 9780-9788
Lazova R , Seeley EH , Kutzner H , Scolyer RA , Scott G , Cerroni L , Fried I , Kozovska ME , Rosenberg AS , Prieto VG , Shehata BM , Durham MM , Henry G , Rodriguez-Peralto JL , Riveiro-Falkenbach E , Schaefer JT , Danialan R , Fraitag S , Vollenweider-Roten S , Sepehr A , Sangueza M , Hijazi N , Corredoira Y , Kowal R , Harris OM , Bravo F , Boyd AS , Gueorguieva R , Caprioli RM , Imaging mass spectrometry assists in the classification of diagnostically challenging atypical Spitzoid neoplasms Journal of the American Academy of Dermatology. 2016 Aug 5; 75 (6). 1176-1186.e4
Van Driest SL , Marshall MD , Hachey B , Beck C , Crum K , Owen J , Smith AH , Kannankeril PJ , Woodworth A , Caprioli RM , Choi L , Pragmatic pharmacology: population pharmacokinetic analysis of fentanyl using remnant samples from children after cardiac surgery British journal of clinical pharmacology. 2016 Jun 8; 81 (6). 1165-74
Lagarrigue M , Caprioli RM , Pineau C , Potential of MALDI imaging for the toxicological evaluation of environmental pollutants Journal of proteomics. 2016 May 10; 144 133-9
Marien E , Meister M , Muley T , Gomez Del Pulgar T , Derua R , Spraggins JM , Van de Plas R , Vanderhoydonc F , Machiels J , Binda MM , Dehairs J , Willette-Brown J , Hu Y , Dienemann H , Thomas M , Schnabel PA , Caprioli RM , Lacal JC , Waelkens E , Swinnen JV , Phospholipid profiling identifies acyl chain elongation as a ubiquitous trait and potential target for the treatment of lung squamous cell carcinoma Oncotarget. 2016 Mar 15; 7 (11). 12582-97

2015

de Macedo| Anderson| Pascarelli| Spraggins| Sarno| Schey| Pessolani CS| DM| BM| JM| EN| KL| MC , MALDI imaging reveals lipid changes in the skin of leprosy patients before and after multidrug thera… Journal of mass spectrometry : JMS. 2015 Dec ; 50 (12). 1374-85
Alomari| Glusac| Choi| Hui| Seeley| Caprioli| Watsky| Urban| Lazova AK| EJ| J| P| EH| RM| KL| J| R , Congenital nevi versus metastatic melanoma in a newborn to a mother with malignant melanoma – diagno… Journal of Cutaneous Pathology. 2015 Oct ; 10 (42).
Anderson| Spraggins| Rose| Schey DM| JM| KL| KL , High spatial resolution imaging mass spectrometry of human optic nerve lipids and proteins. Journal of the American Society for Mass Spectrometry. 2015 Jun ; 26 (6). 940-7
Nagathihalli| Castellanos| Shi| Beesetty| Reyzer| Caprioli| Chen| Walsh| Skala| Moses| Merchant NS| JA| C| Y| ML| R| X| AJ| MC| HL| NB , Signal Transducer and Activator of Transcription 3, Mediated Remodeling of the Tumor Microenvironmen… Gastroenterology. 2015 Dec ; 149 (7). 1932-1943.e9
Marien| Meister| Muley| Fieuws| Bordel| Derua| Spraggins| Van de Plas| Dehairs| Wouters| Bagadi| Dienemann| Thomas| Schnabel| Caprioli| Waelkens| Swinnen E| M| T| S| S| R| J| R| J| J| M| H| M| PA| RM| E| JV , Non-small cell lung cancer is characterized by dramatic changes in phospholipid profiles. International journal of cancer. Journal international du cancer. 2015 Oct 1; 137 (7). 1539-48
Floyd| Moore| Eberly| Good| Shaffer| Zaver| Almqvist| Skaar| Caprioli| Hadjifrangiskou KA| JL| AR| JA| CL| H| F| EP| RM| M , Adhesive fiber stratification in uropathogenic Escherichia coli biofilms unveils oxygen-mediated con… PLOS Pathogens. 2015 Mar 4; 11
Boyer| Anderson| Spraggins| Schey| Hanneken| Ablonczy| Crouch| Koutalos L| NP| DM| JM| KL| A| Z| RK| Y , Determination of N-retinylidene-N-retinylethanolamine (A2E) levels in central and peripheral areas o… Photochemical and Photobiological Sciences. 2015 ; 14 (11). 1983-1990
Caprioli RM , Imaging mass spectrometry: enabling a new age of discovery in biology and medicine through molecular… Journal of the American Society for Mass Spectrometry. 2015 Jun ; 26 (6). 850-2
Bowrey| Anderson| Pallitto| Gutierrez| Fan| Crouch| Schey| Ablonczy HE| DM| P| DB| J| RK| KL| Z , Imaging mass spectrometry of the visual system: Advancing the molecular understanding of retina dege… Proteomics. Clinical applications. 2015 Nov 20;
Prentice| Chumbley| Caprioli BM| CW| RM , High-speed MALDI MS/MS imaging mass spectrometry using continuous raster sampling. Journal of mass spectrometry : JMS. 2015 Apr ; 50 (4). 703-10
Taverna| Boraldi| De Santis| Caprioli| Quaglino D| F| G| RM| D , Histology-directed and imaging mass spectrometry: An emerging technology in ectopic calcification. Bone. 2015 May ; 74 83-94
Van de Plas| Yang| Spraggins| Caprioli R| J| J| RM , Image fusion of mass spectrometry and microscopy: a multimodality paradigm for molecular tissue mapp… Nature methods. 2015 Apr ; 12 (4). 366-72
Spraggins| Rizzo| Moore| Rose| Hammer| Skaar| Caprioli JM| DG| JL| KL| ND| EP| RM , MALDI FTICR IMS of Intact Proteins: Using Mass Accuracy to Link Protein Images with Proteomics Data Journal of The American Society for Mass Spectrometry. 2015 Jun ; 26 (6). 974-985
Gessel| Spraggins| Voziyan| Hudson| Caprioli M| JM| P| BG| RM , Decellularization of intact tissue enables MALDI imaging mass spectrometry analysis of the extracell… Journal of mass spectrometry : JMS. 2015 Nov ; 50 (11). 1288-93
Wenke| Rose| Spraggins| Schey JL| KL| JM| KL , MALDI Imaging Mass Spectrometry Spatially Maps Age-Related Deamidation and Truncation of Human Lens … Investigative ophthalmology & visual science. 2015 Nov 1; 56 (12). 7398-405
Taverna| Norris| Caprioli D| JL| RM , Histology-directed microwave assisted enzymatic protein digestion for MALDI MS analysis of mammalian… Analytical chemistry. 2015 Jan 6; 87 (1). 670-6
Zavalin| Yang| Hayden| Vestal| Caprioli A| J| K| M| RM , Tissue protein imaging at 1 μm laser spot diameter for high spatial resolution and high imaging sp… Analytical and bioanalytical chemistry. 2015 Mar ; 407 (8). 2337-42
Anderson| Floyd| Barnes| Clark| Clark| Mchaourab| Schey DM| KA| S| JM| JI| H| KL , A method to prevent protein delocalization in imaging mass spectrometry of non-adherent tissues: app… Analytical and bioanalytical chemistry. 2015 Mar ; 407 (8). 2311-20
Taverna| Pollins| Sindona| Caprioli| Nanney D| AC| G| RM| LB , Imaging mass spectrometry for assessing cutaneous wound healing: analysis of pressure ulcers. Journal of proteome research. 2015 Feb 6; 14 (2). 986-96

2014

Yang| Caprioli J| RM , Matrix pre-coated targets for high throughput MALDI imaging of proteins. Journal of mass spectrometry : JMS. 2014 May ; 49 (5). 417-22
Verbeeck| Yang| De Moor| Caprioli| Waelkens| Van de Plas N| J| B| RM| E| R , Automated anatomical interpretation of ion distributions in tissue: linking imaging mass spectrometr… Analytical chemistry. 2014 Sep 16; 86 (18). 8974-82
Gessel| Norris| Caprioli MM| JL| RM , MALDI imaging mass spectrometry: spatial molecular analysis to enable a new age of discovery. Journal of proteomics. 2014 Jul 31; 107 71-82
Schmidt| Horvath| Ebert| Norris| Seeley| Brown| Gellert| Everheart| Garbett| Grice| Caprioli| Mirnics MJ| S| P| JL| EH| J| L| M| KA| TW| RM| K , Modulation of behavioral networks by selective interneuronal inactivation. Molecular psychiatry. 2014 May ; 19 (5). 580-7
Moore| Becker| Nicklay| Boyd| Skaar| Caprioli JL| KW| JJ| KL| EP| RM , Imaging mass spectrometry for assessing temporal proteomics: analysis of calprotectin in Acinetobact… Proteomics. 2014 Apr ; 14 (7-8). 820-8
Moore| Caprioli| Skaar JL| RM| EP , Advanced mass spectrometry technologies for the study of microbial pathogenesis. Current opinion in microbiology. 2014 Jun ; 19 45-51
Grove| Voziyan| Spraggins| Wang| Paueksakon| Harris| Hudson| Caprioli KJ| PA| JM| S| P| RC| BG| RM , Diabetic nephropathy induces alterations in the glomerular and tubule lipid profiles. Journal of lipid research. 2014 May 26; 55 (7). 1375-1385
Anderson| Ablonczy| Koutalos| Spraggins| Crouch| Caprioli| Schey DM| Z| Y| J| RK| RM| KL , High resolution MALDI imaging mass spectrometry of retinal tissue lipids. Journal of the American Society for Mass Spectrometry. 2014 Aug ; 25 (8). 1394-403
Ablonczy| Smith| Anderson| Grey| Spraggins| Koutalos| Schey| Crouch Z| N| DM| AC| J| Y| KL| RK , The utilization of fluorescence to identify the components of lipofuscin by imaging mass spectrometr… Proteomics. 2014 Apr ; 14 (7-8). 936-44
Libes| Seeley| Li| Axt| Pierce| Correa| Newton| Hansen| Judd| McDonald| Caprioli| Naranjo| Huff| O'Neill| Lovvorn| JM| EH| M| JR| J| H| M| E| A| H| RM| A| V| JA| HN| , Race disparities in peptide profiles of North American and Kenyan Wilms tumor specimens. Journal of the American College of Surgeons. 2014 Apr ; 218 (4). 707-20
Zavalin| Yang| Haase| Holle| Caprioli A| J| A| A| R , Implementation of a Gaussian beam laser and aspheric optics for high spatial resolution MALDI imagin… Journal of the American Society for Mass Spectrometry. 2014 Jun ; 25 (6). 1079-82
Manier| Spraggins| Reyzer| Norris| Caprioli ML| JM| ML| JL| RM , A derivatization and validation strategy for determining the spatial localization of endogenous amin… Journal of mass spectrometry : JMS. 2014 Aug ; 49 (8). 665-73

2013

McClure| Chumbley| Reyzer| Wilson| Caprioli| Gore| Pham RA| CW| ML| K| RM| JC| W , Identification of promethazine as an amyloid-binding molecule using a fluorescence high-throughput a… NeuroImage. Clinical. 2013 ; 2 620-9
Mike| Dutter| Stauff| Moore| Vitko| Aranmolate| Kehl-Fie| Sullivan| Reid| DuBois| Richardson| Caprioli| Sulikowski| Skaar LA| BF| DL| JL| NP| O| TE| S| PR| JL| AR| RM| GA| EP , Activation of heme biosynthesis by a small molecule that is toxic to fermenting Staphylococcus aureu… Proceedings of the National Academy of Sciences of the United States of America. 2013 May 14; 110 (20). 8206-11
Norris| Caprioli JL| RM , Imaging mass spectrometry: a new tool for pathology in a molecular age. Proteomics. Clinical applications. 2013 Dec ; 7 (11-12). 733-8
Norris| Caprioli JL| RM , Analysis of tissue specimens by matrix-assisted laser desorption/ionization imaging mass spectrometr… Chemical reviews. 2013 Apr 10; 113 (4). 2309-42
Ablonczy| Higbee| Anderson| Dahrouj| Grey| Gutierrez| Koutalos| Schey| Hanneken| Crouch Z| D| DM| M| AC| D| Y| KL| A| RK , Lack of correlation between the spatial distribution of A2E and lipofuscin fluorescence in the human… Investigative ophthalmology & visual science. 2013 Aug ; 54 (8). 5535-42
Kehl-Fie| Zhang| Moore| Farrand| Hood| Rathi| Chazin| Caprioli| Skaar TE| Y| JL| AJ| MI| S| WJ| RM| EP , MntABC and MntH contribute to systemic Staphylococcus aureus infection by competing with calprotecti… Infection and immunity. 2013 Sep ; 81 (9). 3395-405
Ablonczy| Higbee| Grey| Koutalos| Schey| Crouch Z| D| AC| Y| KL| RK , Similar molecules spatially correlate with lipofuscin and N-retinylidene-N-retinylethanolamine in th… Archives of biochemistry and biophysics. 2013 Nov 15; 539 (2). 196-202
Seeley| Washington| Caprioli| M'Koma EH| MK| RM| AE , Proteomic patterns of colonic mucosal tissues delineate Crohn’s colitis and ulcerative colitis. Proteomics. Clinical applications. 2013 Aug ; 7 (7-8). 541-9
Anderson| Mills| Spraggins| Lambert| Calkins| Schey DM| D| J| WS| DJ| KL , High-resolution matrix-assisted laser desorption ionization-imaging mass spectrometry of lipids in r… Molecular vision. 2013 ; 19 581-92
Wattacheril| Seeley| Angel| Chen| Bowen| Lanciault| Caprioli| Abumrad| Flynn J| EH| P| H| BP| C| RM| N| CR , Differential intrahepatic phospholipid zonation in simple steatosis and nonalcoholic steatohepatitis… PloS one. 2013 ; 8 (2). e57165
Reyzer| Park| Allen| Chertov| Kim| Kang| Lee| Caprioli| Kim ML| JW| JL| O| DY| HS| GK| R| HK , MALDI MS profiles distinguish ER-negative breast cancers from lung adenocarcinoma 2013 ; S6:004
Morgan| Seeley| Fadare| Caprioli| Clark TM| EH| O| RM| PE , Imaging the clear cell renal cell carcinoma proteome. The Journal of urology. 2013 Mar ; 189 (3). 1097-103
Zavalin| Yang| Caprioli A| J| R , Laser beam filtration for high spatial resolution MALDI imaging mass spectrometry. Journal of the American Society for Mass Spectrometry. 2013 Jul ; 24 (7). 1153-6
Thiery-Lavenant| Zavalin| Caprioli G| AI| RM , Targeted multiplex imaging mass spectrometry in transmission geometry for subcellular spatial resolu… Journal of the American Society for Mass Spectrometry. 2013 Apr ; 24 (4). 609-14
Harris| Nicklay| Caprioli GA| JJ| RM , Localized in situ hydrogel-mediated protein digestion and extraction technique for on-tissue analysi… Analytical chemistry. 2013 Mar 5; 85 (5). 2717-23
Schey| Grey| Nicklay KL| AC| JJ , Mass spectrometry of membrane proteins: a focus on aquaporins. Biochemistry. 2013 Jun 4; 52 (22). 3807-17
Nicklay| Harris| Schey| Caprioli JJ| GA| KL| RM , MALDI imaging and in situ identification of integral membrane proteins from rat brain tissue section… Analytical chemistry. 2013 Aug 6; 85 (15). 7191-6
Yang| Caprioli J| RM , Matrix precoated targets for direct lipid analysis and imaging of tissue. Analytical chemistry. 2013 Mar 5; 85 (5). 2907-12

2012

Lazova| Seeley| Keenan| Gueorguieva| Caprioli R| EH| M| R| RM , Imaging mass spectrometry–a new and promising method to differentiate Spitz nevi from Spitzoid mali… The American Journal of dermatopathology. 2012 Feb ; 34 (1). 82-90
Ablonczy| Gutierrez| Grey| Schey| Crouch Z| DB| AC| KL| RK , Molecule-specific imaging and quantitation of A2E in the RPE. Advances in experimental medicine and biology. 2012 ; 723 75-81
Hood| Mortensen| Moore| Zhang| Kehl-Fie| Sugitani| Chazin| Caprioli| Skaar MI| BL| JL| Y| TE| N| WJ| RM| EP , Identification of an Acinetobacter baumannii zinc acquisition system that facilitates resistance to … PLoS pathogens. 2012 ; 8 (12). e1003068
Talati| Seeley| Ihida-Stansbury| Delisser| McDonald| Ye| Zhang| Shyr| Caprioli| Meyrick M| E| K| H| H| F| X| Y| R| B , Altered expression of nuclear and cytoplasmic histone H1 in pulmonary artery and pulmonary artery sm… Pulmonary circulation. 2012 Jul ; 2 (3). 340-51
Murphy| Axt| de Caestecker| Pierce| Correa| Seeley| Caprioli| Newton| de Caestecker| Lovvorn AJ| JR| C| J| H| EH| RM| MW| MP| HN , Molecular characterization of Wilms’ tumor from a resource-constrained region of sub-Saharan Africa. International journal of cancer. Journal international du cancer. 2012 Sep 15; 131 (6). E983-94
Zavalin| Todd| Rawhouser| Yang| Norris| Caprioli A| EM| PD| J| JL| RM , Direct imaging of single cells and tissue at sub-cellular spatial resolution using transmission geom… Journal of mass spectrometry : JMS. 2012 Nov ; 47 (11). 1473-81
Thiery| Mernaugh| Yan| Spraggins| Yang| Parl| Caprioli G| RL| H| JM| J| FF| RM , Targeted multiplex imaging mass spectrometry with single chain fragment variable (scfv) recombinant … Journal of the American Society for Mass Spectrometry. 2012 Oct ; 23 (10). 1689-96
Yang| Chaurand| Norris| Porter| Caprioli J| P| JL| NA| RM , Activity-based probes linked with laser-cleavable mass tags for signal amplification in imaging mass… Analytical chemistry. 2012 Apr 17; 84 (8). 3689-95

2011

Yang| Caprioli J| RM , Matrix sublimation/recrystallization for imaging proteins by mass spectrometry at high spatial resol… Analytical chemistry. 2011 Jul 15; 83 (14). 5728-34
Deutskens| Yang| Caprioli F| J| RM , High spatial resolution imaging mass spectrometry and classical histology on a single tissue section… Journal of mass spectrometry : JMS. 2011 Jun ; 46 (6). 568-71
Axt| Murphy| Seeley| Martin| Taylor| Pierce| Caprioli| Whiteside| Lovvorn J| AJ| EH| CA| C| J| RM| M| HN , Race disparities in Wilms tumor incidence and biology. The Journal of surgical research. 2011 Sep ; 170 (1). 112-9
Bowlus| Seeley| Roder| Grigorieva| Roder| Caprioli| Gershwin CL| EH| J| J| H| RM| M , In situ mass spectrometry of autoimmune liver diseases. Cellular & molecular immunology. 2011 May ; 8 (3). 237-42
Hardesty| Kelley| Mi| Low| Caprioli WM| MC| D| RL| RM , Protein signatures for survival and recurrence in metastatic melanoma. Journal of proteomics. 2011 Jun 10; 74 (7). 1002-14
M'Koma| Seeley| Washington| Schwartz| Muldoon| Herline| Wise| Caprioli AE| EH| MK| DA| RL| AJ| PE| RM , Proteomic profiling of mucosal and submucosal colonic tissues yields protein signatures that differe… Inflammatory bowel diseases. 2011 Apr ; 17 (4). 875-83
Taverna| Nanney| Pollins| Sindona| Caprioli D| LB| AC| G| R , Multiplexed molecular descriptors of pressure ulcers defined by imaging mass spectrometry. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. 2011 Nov ; 19 (6). 734-44
Taverna| Nanney| Pollins| Sindona| Caprioli D| LB| AC| G| R , Spatial mapping by imaging mass spectrometry offers advancements for rapid definition of human skin … Experimental dermatology. 2011 Aug ; 20 (8). 642-7
Manier| Reyzer| Goh| Dartois| Via| Barry| Caprioli ML| ML| A| V| LE| CE| RM , Reagent precoated targets for rapid in-tissue derivatization of the anti-tuberculosis drug isoniazid… Journal of the American Society for Mass Spectrometry. 2011 Aug ; 22 (8). 1409-19
Grey| Crouch| Koutalos| Schey| Ablonczy AC| RK| Y| KL| Z , Spatial localization of A2E in the retinal pigment epithelium. Investigative ophthalmology & visual science. 2011 Jun ; 52 (7). 3926-33
Spraggins| Caprioli JM| RM , High-speed MALDI-TOF imaging mass spectrometry: rapid ion image acquisition and considerations for n… Journal of the American Society for Mass Spectrometry. 2011 Jun ; 22 (6). 1022-31
Grove| Frappier| Caprioli KJ| SL| RM , Matrix pre-coated MALDI MS targets for small molecule imaging in tissues. Journal of the American Society for Mass Spectrometry. 2011 Jan ; 22 (1). 192-5
Manna| Reyzer| Latham| Weaver| Marnett| Caprioli JD| ML| JC| CD| LJ| RM , High-throughput quantification of bioactive lipids by MALDI mass spectrometry: application to prosta… Analytical chemistry. 2011 Sep 1; 83 (17). 6683-8
Chacon| Zagol-Ikapitte| Amarnath| Reyzer| Oates| Caprioli| Boutaud A| I| V| ML| JA| RM| O , On-tissue chemical derivatization of 3-methoxysalicylamine for MALDI-imaging mass spectrometry. Journal of mass spectrometry : JMS. 2011 Aug ; 46 (8). 840-6