Role of Caveolin-1 Mutations in Pulmonary Arterial Hypertension
I work in the lab of Dr. Anne Kenworthy where some main interests are microscopy, lipid rafts, autophagy, and endocytosis. Recently, we began collaborating with researchers who are working on Pulmonary Arterial Hypertension (PAH). My thesis project focuses on the membrane protein Caveolin-1 which is involved in endocytosis amongst other things. The Cav-1 mutation we study is associated with PAH, and we would like to better understand the role of this mutated protein in the pathogenesis of the disease.