Diana Contreras

Diana Contreras

Pathology, Microbiology & Immunology

PI: Holly Algood, Ph.D.

The role of IL-21 in inflammation leading to gastric cancer

The Algood lab researches the immunological response to Helicobacter pylori infection, a significant cause of gastric cancer. Our lab looks at a variety of factors that may contribute to inflammation or bacterial clearance. My focus within our lab is the T helper 17 cell response during infection. Studies in our lab have shown that interleukin 21, which is produced by this cell type, plays an important role during infection.  My future research will be to determine the mechanism by which IL-21 drives inflammation, which is believed to be the initial step towards gastric cancer.