Juan Gnecco

Juan Gnecco

Pathology, Microbiology & Immunology

PI: Kevin Osteen, Ph.D.

Developing an organ-on-a-chip model of the uterine endometrium

As part of the Cellular & Molecular Pathology department and Vanderbilt Women's Reproductive Health Research Center we are invested in investigating the inflammatory associated etiology of endometriosis as well as endocrine disrupting environmental toxicants, specifically dioxin (TCDD) that cause trans-generational preterm birth and infertility in both female and male. My project is to engineer an innovative organ-on-a-chip model of the uterine endometrium to study these issues with human primary cells and examine putative preventative approaches.