Publications

2017

58 Chen, Q., Perry, N.A., Zhuo, Y., Vishnivetskiy, S.A., Gilbert, N.C., Zhuo, Y., Berndt, S., Singh, P.K., Tholen, J., Ohi, M.D., Gurevich. E.V., Brautigam, C.A., Klug, C.S., Gurevich, V.V., Iverson, T.M. (2017) Structural basis for arrestin-3 activation and signaling. Nat. Commun., in press.

57 Starbird, C.A., Maklashina, E., Sharma, P., Qualls-Histed, S., Cecchini, G., Iverson, T.M. (2017) Structural and biochemical analyses reveal insights into covalent flavinylation of the Escherichia coli Complex II homolog quinol:fumarate reductase. J Biol Chem. 2017 Aug 4;292(31):12921-12933.

56 Prokop, S., Perry, N.A., Vishnivetskiy, S.A., Toth, A.D., Inoue, A., Milligan, G., Iverson, T.M., Hunyady, L., Gurevich, V.V. (2017) Differential manipulation of arrestin-3 binding to basal and agonist-activated G protein-coupled receptors. Cell Signal. 2017 Aug;36:98-107. doi: 10.1016/j.cellsig.2017.04.021. Epub 2017 Apr 28.

 

2016

55 Loukachevitch, L.V., Bensing, B.A., Yu, H., Zeng, J., Chen, X., Sullam, P.M., Iverson, T. M. (2016) Structures of the Streptococcus sanguinis SrpA Binding Region with Human Sialoglycans Suggest Features of the Physiological Ligand. Biochemistry.  2016 Oct 11.

54 Bensing, B.A., Loukachevitch, L.V., McCulloch, K.M., Yu ,H., Vann, K.R., Wawrzak, Z., Anderson, S., Chen, X., Sullam, P.M., Iverson, T.M. (2016) Structural Basis for Sialoglycan Binding by the Streptococcus sanguinis SrpA Adhesin. J. Biol. Chem.  291(14):7230-40.

53 Maklashina, E., Rajagukguk, S., Starbird, C.A., McDonald, W.H., Koganitsky, A., Eisenbach, M., Iverson, T.M., Cecchini, G. (2016) Binding of the Covalent Flavin Assembly Factor to the Flavoprotein Subunit of Complex II.  J. Biol. Chem.  291(6):2904-16

52 Zhan, X., Stoy, H., Kaoud, T. S., Perry, N. A., Chen, Q., Perez, A., Els-Heindl, S., Slagis, J.V., Iverson, T.M., Beck-Sickinger, A.G., Gurevich, E.V., Dalby, K.N., Gurevich, V. V. (2016). Peptide mini-scaffold facilitates JNK3 activation in cells. Scientific Reports, 6, 21025.

51 Bensing, B.A., Khedri, Z., Deng, L., Yu, H., Prakobphol, A., Fisher, S.J., Chen, X., Iverson, T.M., Varki, A., and Sullam, P.M. (2016) Novel aspects of sialoglycan recognition by the Siglec-like domains of streptococcal SRR glycoproteins. Glycobiology. cww042. [Epub ahead of print]

50 Kaya, A.I., Lokits, A.D., Gilbert, J.A., Iverson, T.M., Meiler, J., Hamm, H.E. (2016) A conserved hydrophobic core in Gαi1 regulates G protein activation and release from activated receptor. J. Biol. Chem. 2016 Sep 9;291(37):19674-86.

 

2015

49 McCulloch, K.M., McCranie, E.K., Smith, J.A., Sarwar, M., Mathieu, J.L., Gitschlag, B.L., Du, Y., Bachmann, B.O., and Iverson, T.M. (2015) Oxidative cyclizations in orthosomycin biosynthesis expand the known chemistry of an oxygenase superfamily. Proc Natl Acad Sci USA. 112(37):11547-52.

48 Starbird, C. A., Maklashina, E., Cecchini, G. and Iverson, T.M. (2015) Flavoenzymes: Covalent versus Noncovalent. eLS. 1–11.

47 Chen, Q., Vishnivetskiy, S.A., Zhuang, T., Cho, M.K., Thaker, T.M., Sanders, C.R., Gurevich, V.V., and Iverson, T.M. (2015) The rhodopsin-arrestin-1 interaction in bicelles. Methods Mol. Biol. 1271:77-95

46 Kaya, A.I., Iverson T.M., and Hamm, H.E. (2015) Functional stability of rhodopsin in a bicelle system: evaluating G protein activation by rhodopsin in bicelles. Methods Mol. Biol. 1271:67-76

2014

45 Birmingham, W.R., Nannemann, D.P., Starbird, C.A., Panosian, T.D., Iverson T.M., and Bachmann, B.O. (2014) Bioretrosynthetic construction of a didanosine biosynthetic pathway. Nat. Chem. Biol. 10(5):392-399

44 Kaya, A.I., Lokits, A.D., Gilbert, J.A., Iverson, T.M., Meiler, J., and Hamm, H.E. (2014) A conserved phenylalanine as a relay between the α5 helix and the GDP binding region of heterotrimeric Gi protein α subunit.  J. Biol. Chem. 289(35):24475-24487

43 Thaker, T.M., Preininger, A.M., Sarwar, M., Hamm, H.E., and Iverson T.M. (2014) A transient interaction between the P-loop and Switch I contributes to the allosteric network between receptor and nucleotide in Gαi1. J. Biol. Chem. 289(16):11331-11341

42 Vishnivetskiy, S.A., Zhan, X., Chen, Q., Iverson, T.M., and Gurevich, V.V. (2014) Arrestin expression in E. coli and purification.  Curr. Protoc. Pharmacol. 67(Unit 2.11)

2013

41 Zhuang T., Chen Q., Cho M.K., Vishnivetskiy S.A., Iverson T.M., Gurevich V.V., and Sanders C.R. (2013) Involvement of distinct arrestin-1 elements in binding to different functional forms of rhodopsin. Proc Natl Acad Sci USA 110(3): 942-947

40 Seo, H.S., Misanov, G., Seepersaud, R., Doran, K.S., Dubrovska, I., Shuvalova, L., Anderson, W.F., Iverson T.M., and Sullam, P.M. (2013) Characterization of Fibrinogen Binding by Glycoproteins Srr1 and Srr2 of Streptococcus agalactiae. J. Biol. Chem. 288(50): 35982-35996

39 Singh P.K., Sarwar M., Maklashina E., Kotlyar V., Rajaqukquk S., Tomasiak T.M., Cecchini G., Iverson T.M. (2013) Plasticity of the Quinone-Binding Site of the Complex II Homolog Quinol:Fumarate Reductase. J. Biol Chem. PMID: 23836905

38 Vishnivetskiy S.A., Chen Q., Palazzo M.C., Brooks E.K., Altenbach C., Iverson T.M., Hubbell W.L., and Gurevich V.V. (2013) Engineering visual arrestin-1 with special functional characteristics. J Biol Chem 288(5): 3394-405.

37 Thaker T.M., Tanabe M., Fowler M.L., Preininger A.M., Ingram-Smith C., Smith K.S., and Iverson T.M. (2013) Crystal structures of acetate kinases from the eukaryotic pathogens Entamoeba histolytica and Cryptococcus neoformans. J Struct Biol. 181(2):185-9.

2012

36 Iverson T.M., Panosian, T.D., Birmingham, W., Nannemann, D. P., and Bachmann, B.O. (2012) Molecular differences between a mutase and a phosphatase: investigations of the activation step in Bacillus cereus phosphopentomutase. Biochemistry. 51(9): 1964-1975. PMID: 22329805, PMCID:PMC3302354

35 Iverson T.M. (2012) Catalytic mechanisms of complex II enzymes: A structural perspective. Biochim Biophys Acta. Sep 18. pii: S0005-2728(12) 01031-6. PMID: 22995215, PMCID:PMC3537904

34 Iverson T.M., Maklashina E., and Cecchini G. (2012) Structural basis for malfunction in complex II. J Biol Chem. 287(42): 35430-8. PMID:22904323, PMCID:PMC3471735

2011

33 Pyburn, T.M., Bensing, B.A., Melancon, B.J., Tomasiak, T.M., Yankovskaya, V., Oliver, K., Ward, N.J., Sulikowski, G.A., Cecchini, G., Tyska, M.J., Sullam, P.M., and Iverson, T.M. (2011) A structural model for binding of the serine-rich repeat adhesin GspB to host carbohydrate receptors. PLoS Pathogens. 7(7): e1002112. PMCID:PMC3131266

32 Kuchtey, J., Olson, L.M., Rinkoski, T., MacKay, E.O., Iverson, T.M.,Gelatt, K.N., Haines, J.L. and Kuchtey, R.W. (2011) Mutation in ADAMTS10 in a canine model of primary open angle glaucoma. PLoS Genetics. 7(2): e1001306. PMCID:PMC3040645

31 Kaya, A.I., Thaker, T.M., Preininger, A.M., Iverson, T.M., and Hamm, H.E. (2011) Coupling efficiency of rhodopsin and transducin in bicelles. Biochemistry. 50(15): 3193-3203. PMCID:PMC3119548

30 Thaker, T.M., Kaya, A.I., Preininger, A.M., Hamm, H.E., and Iverson, T.M., (2011) Allosteric Mechanisms of G protein Coupled Receptor Signaling: A Structural Perspective, in A. Fenton (ed.) Methods in Molecular Biology - Allostery: Methods and Protocols, Humana Press, New York, NY. (2011) Part II, Chapter 8, pp. 133-174.

29 Panosian, T.D., Nannemann, D.P., Watkins, G., Wadzinski, B., Bachmann, B.O., and Iverson, T.M. (2011) Bacillus cereus phosphopentomutase is an alkaline phosphatase family member that exhibits an altered catalytic cycle. J. Biol Chem. 286(10): 8043-8054. PMCID:PMC3048691

28 Tomasiak, T.M., Archuleta, T.L., Andréll, J., Luna-Chavez, C., Davis, T., Sarwar, M., Ham, A.J., McDonald, H., Yankovskaya, V., Maklashina, E., Stern, H.A., Johnston, J.N., Cecchini, G., and Iverson, T.M. (2011) Geometric restraints drive on- and off-pathway catalysis in the Escherichia coli menaquinol:fumarate reductase. J. Biol. Chem. 286(4): 3047-3056. PMCID:PMC3024798

2010

27 Tanabe M., Nimigean C.M., Iverson, T.M. (2010) Structural basis for solute transport, nucleotide regulation, and immunological recognition of Neisseria meningitidis PorB. Proc. Natl. Acad. Sci. USA. 107(15): 6811-6816. PMCID:PMC2872391

26 Vey J.L., Al-Mestarihi A., Funk M.A., Bachmann B.O., Iverson T.M. (2010) Structure and mechanism of ORF36, an amino sugar oxidizing enzyme in everninomicin biosynthesis. Biochemistry. 49(43): 9306-9317. PMCID:PMC2964426

25 Pyburn T., Bensing B., Yankovskaya V., Sullam P.M., Iverson T.M. (2010) Purification, crystallization, and preliminary x-ray diffraction analysis of the carbohydrate binding region of the Streptococcus gordonii adhesin GspB. Acta crystallogr. 

24 Panosian T.D., Nannemann D.P., Bachmann B.O., Iverson T.M. (2010) Crystallization and preliminary X-ray analysis of a phosphopentomutase from Bacillus cereus. Acta Crystallogr. F66(7): 811-814. PMCID:PMC2898468

2009

23 Thompson A.N., Kim I., Panosian T.D., Iverson T.M., Allen W.A., Nimigean C.M. (2009) Mechanism of potassium-channel selectivity revealed by Na+ and Li+ binding sites within the KcsA pore. Nat. Struct. & Molec Biol. 16(12): 1317-U1143. PMCID:PMC2825899

22 Adler D.H., Phillips J.A., Cogan J.D., Iverson T.M., Stein J.A., et al. (2009) The enteropathy of prostaglandin deficiency. J. Gastroenterol. 44(Suppl 19): 1-7. PMCID:PMC2799331

21 Preininger, A. M., Funk, M. A., Meier, S. M., Oldham, W. M., Johnston, C. A., Adhikary, S., … Iverson, T. M. (2009). Helix dipole movement and conformational variability contribute to allosteric GDP release in Gαi subunits. Biochemistry, 48(12), 2630–2642. doi:10.1021/bi801853a PMCID:PMC2736342

20 Tanabe M., Iverson T.M. (2009) Expression, purification and preliminary X-ray analysis of the Neisseria meningitidis outer membrane protein PorB. Acta Crystallogr. F65(10): 996-1000. PMCID:PMC2765884

19 Tanabe M., Iverson T.M. (2009) A Practical Guide to X-Ray Crystallography of beta-barrel Membrane Proteins: Expression, Purification, Detergent Selection, and Crystallization. Membrane Protein Crystallization: 63, 229-267.

2008

18 Tomasiak T.M., Maklashina E., Cecchin, G., Iverson, T.M. (2008) A threonine on the active site loop controls transition state formation in Escherichia coli respiratory complex II. J. Biol Chem. 283(22): 15460-15468. PMCID:PMC2397489

17 Cecchini G., Maklashina E., Tomasiak T.M., Iverson T.M. Conformational Changes at the Dicarboxylate Binding Site of Succinate Dehydrogenase (Complex II) and Fumarate Reductase, in Frago S., Gomez-Moeno C, Medina M. (eds.) Flavins and Flavoproteins, Prensas Universitarias de Zaragoza (2008) pp. 17-26.

16 Adler D.H., Cogan J.D., Phillips J.A., Schnetz-Boutaud N., Milne G.L, Iverson T.M., Stein J.A., Brenner D.A., Morrow J.D., Boutaud O., Oates J.A. (2008) Inherited human cPLA2α deficiency is associated with impaired eicosanoid biosynthesis, small intestinal ulceration, and platelet dysfunction. J. Clin. Invest. 118:2121-2131. PMCID:PMC2735913

2007

15 Tomasiak, T, Cecchini, G, Iverson, T.M. 2007. Succinate as Donor; Fumarate as Acceptor, EcoSal Plus 2007; doi:10.1128/ecosal.3.2.6 ASM Press, Washington, D.C.

2006

14 Iverson T.M. (2006) Evolution and unique bioenergetic mechanisms in oxygenic photosynthesis. Curr Opin Chem Biol. 10(2): 91-100. PMID: 16504567

13 Maklashina E., Iverson T.M., Sher Y., Kotlyar V., Andréll J., Mirza O., Hudson J.M., Armstrong F.A., Rothery R.A., Weiner J.H., Cecchini G. (2006) Fumarate reductase and succinate oxidase activity of Escherichia coli complex II homologs are perturbed differently by mutation of the flavin binding domain. J. Biol. Chem. 281(16): 11357-11365. PMID: 16484232

2004

12 Ferreira K.N., Iverson T.M., Maghaloui K., Iwata S, and Barber J. (2004) Architecture of the oxygen evolving centre of photosystem II. Science, 303(5665): 1831-1838 co-first author. PMID: 14764885

2003

11 Cecchini G., Maklashina E., Yankovskaya V., Iverson T.M., Iwata S. (2003) Variation in proton donor/acceptor pathways in succinate:quinone oxidoreductases. FEBS Lett. 545(1), 31-8. PMID: 12788489

2002

10 Doukov T.I., Iverson T.M., Seravalli J., Ragsdale S.W., Drennan C.L. (2002) A Ni-Fe-Cu center in a bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase. Science, 298(5593), 567-72. PMID: 12386327

9 Iyer R., Iverson T.M., Accardi A., Miller C. (2002) A biological role for prokaryotic ClC chloride channels. Nature, 419(6908), 715-8.

8 Iverson T.M., Luna-Chavez C., Croal L.R., Cecchini G., Rees D.C. (2002) Crystallographic studies of the Escherichia coli quinol-fumarate reductase with inhibitors bound to the quinol-binding site. J Biol Chem, 277(18), 16124-30. PMID: 11850430

2001

7 Iverson T.M., Arciero D.M., Hooper A.B., Rees D.C. (2001) High-resolution structures of the oxidized and reduced states of cytochrome c554 from Nitrosomonas europaea. J Biol Inorg Chem, 6(4), 390-7. PMID: 11372197

6 Strop P., Smith K.S., Iverson T.M., Ferry J.G., Rees D.C. (2001) Crystal structure of the 'cab'-type beta class carbonic anhydrase from the archaeon Methanobacterium thermoautotrophicum. J Biol Chem, 276(13), 10299-305. PMID: 11096105

2000

5 Iverson T.M., Alber B.E., Kisker C., Ferry J.G., Rees D.C. (2000) A closer look at the active site of gamma-class carbonic anhydrases: high-resolution crystallographic studies of the carbonic anhydrase from Methanosarcina thermophila. Biochemistry, 39(31), 9222-31. PMID: 10924115

4 Iverson, T.M., Luna-Chavez, C, Schröder, I, Cecchini, G, Rees, D C. (2000) Analyzing your complexes: structure of the quinol-fumarate reductase respiratory complex. Curr Opin Struct Biol, 10(4), 448-55. PMID: 10981634

3 Luna-Chavez C., Iverson T. M., Rees D.C., Cecchini G. (2000) Overexpression, purification, and crystallization of the membrane-bound fumarate reductase from Escherichia coli. Protein Expr Purif, 19(1), 188-96. PMID: 10833406

1999

2 Iverson T.M., Luna-Chavez C., Cecchini G., Rees D.C. (1999) Structure of the Escherichia coli fumarate reductase respiratory complex. Science, 284(5422), 1961-6. PMID: 10373108

1998

1 Iverson T.M., Arciero D.M., Hsu B.T., Logan M.S., Hooper A.B., Rees D C. (1998) Heme packing motifs revealed by the crystal structure of the tetra-heme cytochrome c554 from Nitrosomonas europaea. Nat Struct Biol, 5(11), 1005-12. PMID: 9808046