Michelle Mitchener

Michelle Mitchener

Graduate Student

I am a native of Troy, MI, who pursued her undergraduate studies at Cedarville University (near Dayton, OH). After graduating in 2012 with a double major in chemistry and molecular & cellular biology, I followed my passion for both chemistry and biology to Vanderbilt University and, ultimately, to the Marnett lab. Here, I am using chemical biology approaches to interrogate the function of proteins involved in oxidative lipid metabolism.

Outside of the lab, I enjoy running, singing, and visiting family.

Publications

Nuclear Oxidation of a Major Peroxidation DNA Adduct, M1dG, in the Genome, Wauchope OR, Beavers WN, Galligan JJ, Mitchener MM, Kingsley PJ, Marnett LJ., Chem Res Toxicol. 2015 Dec 21;28(12):2334-42. doi: 10.1021/acs.chemrestox.5b00340. Epub 2015 Nov 11
PMID: 26469224

Competition and allostery govern substrate selectivity of cyclooxygenase-2, Mitchener MM, Hermanson DJ, Shockley EM, Brown HA, Lindsley CW, Reese J, Rouzer CA, Lopez CF, Marnett LJ, Proc Natl Acad Sci U S A. 2015 Oct 6;112(40):12366-71. doi: 10.1073/pnas.1507307112. Epub 2015 Sep 21. Erratum in: Proc Natl Acad Sci U S A. 2016 Mar 8;113(10):E1413
PMID: 26392530

PubMed Search for Michelle Mitchener

Presentations

"Competition and Allostery Govern Substrate Selectivity of Cyclooxygenase-2," 2015 Oral Presentation, Vanderbilt Institute of Chemical Biology Student Research Symposium (begin at 4:19):

https://www.youtube.com/watch?v=CHl7KznP4LQ