Alpha to Beta Cell Reprogramming: Stepping toward a New Treatment for Diabetes.
AUTHORS
Osipovich
AB ,
Magnuson
MA ,
. Cell stem cell. 2018 1 4; 22(1). 12-13
- PMID: 29304337 [PubMed].
ABSTRACT
Beta cell replacement strategies hold promise for permanently treating type 1 diabetes. In Cell Stem Cell, Xiao et al. (2018) restore pancreatic beta cell mass and normalize blood glucose in diabetic mice by reprogramming pancreatic alpha to beta cells using Pdx1- and Mafa-expressing adeno-associated virus infused into the pancreatic duct.
Beta cell replacement strategies hold promise for permanently treating type 1 diabetes. In Cell Stem Cell, Xiao et al. (2018) restore pancreatic beta cell mass and normalize blood glucose in diabetic mice by reprogramming pancreatic alpha to beta cells using Pdx1- and Mafa-expressing adeno-associated virus infused into the pancreatic duct.
Tags: 2018