• Noehren B, Andersen A, Hardy P, Johnson DL, Ireland ML, Thompson KL, Damon B. Cellular and Morphological Alterations in the Vastus Lateralis Muscle as the Result of ACL Injury and Reconstruction. The Journal of bone and joint surgery. American volume. 2016 Sep 21;98(18). 1541-7. PMID: 27655981 [PubMed]. PMCID: PMC5026157.


Individuals who have had an anterior cruciate ligament (ACL) tear and reconstruction continue to experience substantial knee extensor strength loss despite months of physical therapy. Identification of the alterations in muscle morphology and cellular composition are needed to understand potential mechanisms of muscle strength loss, initially as the result of the injury and subsequently from surgery and rehabilitation.