Circadian Clocks: Unexpected Biochemical Cogs.
AUTHORS
Mori
T ,
Mchaourab
H ,
Johnson
CH ,
. Current biology : CB. 2015 10 5; 25(19). R842-4
- PMID: 26439342 [PubMed].
- PMCID: PMC4697453.
- NIHMSID: NIHMS744952
ABSTRACT
A circadian oscillation can be reconstituted in vitro from three proteins that cycles with a period of ∼ 24 h. Two recent studies provide surprising biochemical answers to why this remarkable oscillator has such a long time constant and how it can switch effortlessly between alternating enzymatic modes.
A circadian oscillation can be reconstituted in vitro from three proteins that cycles with a period of ∼ 24 h. Two recent studies provide surprising biochemical answers to why this remarkable oscillator has such a long time constant and how it can switch effortlessly between alternating enzymatic modes.
Tags: 2015