Early Detection of Treatment-Induced Mitotic Arrest Using Temporal Diffusion Magnetic Resonance Spectroscopy.
AUTHORS
Jiang
X ,
Li
H ,
Zhao
P ,
Xie
J ,
Khabele
D ,
Xu
J ,
Gore
JC ,
. Neoplasia (New York, N.Y.). 2016 12 ; 18(6). 387-97
- PMID: 27292027 [PubMed].
- PMCID: PMC4909704.
ABSTRACT
A novel quantitative magnetic resonance imaging (MRI) method, namely, temporal diffusion spectroscopy (TDS), was used to detect the response of tumor cells (notably, mitotic arrest) to a specific antimitotic treatment (Nab-paclitaxel) in culture and human ovarian xenografts and evaluated as an early imaging biomarker of tumor responsiveness.
A novel quantitative magnetic resonance imaging (MRI) method, namely, temporal diffusion spectroscopy (TDS), was used to detect the response of tumor cells (notably, mitotic arrest) to a specific antimitotic treatment (Nab-paclitaxel) in culture and human ovarian xenografts and evaluated as an early imaging biomarker of tumor responsiveness.
Tags: 2016