• Harkins KD, Xu J, Dula AN, Li K, Valentine WM, Gochberg DF, Gore JC, Does MD. The microstructural correlates of T1 in white matter. Magnetic resonance in medicine. 2016 Mar;75(3). 1341-5. PMID: 25920491 [PubMed]. PMCID: PMC4624612. NIHMSID: NIHMS678390.

Abstract 

Several studies have shown strong correlations between myelin content and T1 within the brain, and have even suggested that T1 can be used to estimate myelin content. However, other micro-anatomical features such as compartment size are known to affect longitudinal relaxation rates, similar to compartment size effects in porous media.