- Bregman JA, Herren DJ, Estopinal CB, Chocron IM, Harlow PA, Warden C, Brantley MA, Samuels DC. Mitochondrial Haplogroups Affect Severity But Not Prevalence of Diabetic Retinopathy. Investigative ophthalmology & visual science. 2017 Feb 1;58(2). 1346-1351. PMID: 28245487 [PubMed].
We previously reported European mitochondrial haplogroup H to be a risk factor for and haplogroup UK to be protective against proliferative diabetic retinopathy (PDR) among Caucasian patients with diabetic retinopathy (DR). The purpose of this study was to determine whether these haplogroups are also associated with the risk of having DR among Caucasian patients with diabetes.