Skip to main content

Pleiotropic and sex-specific effects of cancer GWAS SNPs on melanoma risk in the population architecture using genomics and epidemiology (PAGE) study.


AUTHORS

Kocarnik JM , Park SL , Han J , Dumitrescu L , Cheng I , Wilkens LR , Schumacher FR , Kolonel L , Carlson CS , Crawford DC , Goodloe RJ , Dilks HH , Baker P , Richardson D , Matise TC , Ambite JL , Song F , Qureshi AA , Zhang M , Duggan D , Hutter C , Hindorff L , Bush WS , Kooperberg C , Le Marchand L , Peters U , . PloS one. 2015 ; 10(3). e0120491

ABSTRACT

Several regions of the genome show pleiotropic associations with multiple cancers. We sought to evaluate whether 181 single-nucleotide polymorphisms previously associated with various cancers in genome-wide association studies were also associated with melanoma risk.


Several regions of the genome show pleiotropic associations with multiple cancers. We sought to evaluate whether 181 single-nucleotide polymorphisms previously associated with various cancers in genome-wide association studies were also associated with melanoma risk.


Tags: