Renal Denervation Prevents Immune Cell Activation and Renal Inflammation in Angiotensin II-Induced Hypertension.
AUTHORS
Xiao
L ,
Kirabo
A ,
Wu
J ,
Saleh
MA ,
Zhu
L ,
Wang
F ,
Takahashi
T ,
Loperena
R ,
Foss
JD ,
Mernaugh
RL ,
Chen
W ,
Roberts
J ,
Osborn
JW ,
Itani
HA ,
Harrison
DG ,
. Circulation research. 2015 8 28; 117(6). 547-57
- PMID: 26156232 [PubMed].
- PMCID: PMC4629828.
- NIHMSID: NIHMS706824
ABSTRACT
Inflammation and adaptive immunity play a crucial role in the development of hypertension. Angiotensin II and probably other hypertensive stimuli activate the central nervous system and promote T-cell activation and end-organ damage in peripheral tissues.
Inflammation and adaptive immunity play a crucial role in the development of hypertension. Angiotensin II and probably other hypertensive stimuli activate the central nervous system and promote T-cell activation and end-organ damage in peripheral tissues.
Tags: 2015