{"id":2245,"date":"2018-03-23T00:00:00","date_gmt":"2018-03-23T00:00:00","guid":{"rendered":"https:\/\/medschool.prd.vanderbilt.edu\/mpb\/2018\/03\/23\/congratulations-to-david-jacobson-another-r01\/"},"modified":"2018-03-23T00:00:00","modified_gmt":"2018-03-23T00:00:00","slug":"congratulations-to-david-jacobson-another-r01","status":"publish","type":"post","link":"https:\/\/medschool.vanderbilt.edu\/mpb\/2018\/03\/23\/congratulations-to-david-jacobson-another-r01\/","title":{"rendered":"Congratulations to David Jacobson!  Another R01&#8230;.."},"content":{"rendered":"<p>The new grant (<a href=\"https:\/\/projectreporter.nih.gov\/project_info_description.cfm?aid=9423105&amp;icde=38694963\">1R01DK115620-01<\/a>), titled DESIGNING SELECTIVE TALK-1 INHIBITORS TO REDUCE BETA-CELL DYSFUNCTION IN DIABETES, will test the central hypothesis that the inhibition of TALK-1 potassium channels in pancreatic beta cells normalizes Ca<sup>2+<\/sup> homeostasis under diabetic conditions, preventing beta-cell dysfunction and maintaining euglycemia.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The new grant (1R01DK115620-01), titled DESIGNING SELECTIVE TALK-1 INHIBITORS TO REDUCE BETA-CELL DYSFUNCTION IN DIABETES, will test the central hypothesis that the inhibition of TALK-1 potassium channels in pancreatic beta cells normalizes Ca2+ homeostasis under diabetic conditions, preventing beta-cell dysfunction and maintaining euglycemia.<\/p>\n","protected":false},"author":586,"featured_media":1637,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[1],"tags":[],"class_list":["post-2245","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized"],"acf":[],"jetpack_featured_media_url":"https:\/\/cdn.vanderbilt.edu\/t2-main\/medschool-prd\/wp-content\/uploads\/sites\/13\/2018\/09\/Jacobson_0.jpg","ACF":false,"_links":{"self":[{"href":"https:\/\/medschool.vanderbilt.edu\/mpb\/wp-json\/wp\/v2\/posts\/2245","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medschool.vanderbilt.edu\/mpb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medschool.vanderbilt.edu\/mpb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medschool.vanderbilt.edu\/mpb\/wp-json\/wp\/v2\/users\/586"}],"replies":[{"embeddable":true,"href":"https:\/\/medschool.vanderbilt.edu\/mpb\/wp-json\/wp\/v2\/comments?post=2245"}],"version-history":[{"count":0,"href":"https:\/\/medschool.vanderbilt.edu\/mpb\/wp-json\/wp\/v2\/posts\/2245\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medschool.vanderbilt.edu\/mpb\/wp-json\/wp\/v2\/media\/1637"}],"wp:attachment":[{"href":"https:\/\/medschool.vanderbilt.edu\/mpb\/wp-json\/wp\/v2\/media?parent=2245"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medschool.vanderbilt.edu\/mpb\/wp-json\/wp\/v2\/categories?post=2245"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medschool.vanderbilt.edu\/mpb\/wp-json\/wp\/v2\/tags?post=2245"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}