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Master of Public Health

Comparison of Etomidate and Ketamine for Induction During Rapid Sequence Intubation of Adult Trauma Patients.

AUTHORS

Upchurch CP , Grijalva CG , Russ S , Collins SP , Semler MW , Rice TW , Liu D , Ehrenfeld JM , High K , Barrett TW , McNaughton CD , Self WH , . Annals of emergency medicine. 2017 1 ; 69(1). 24-33.e2

ABSTRACT

Induction doses of etomidate during rapid sequence intubation cause transient adrenal dysfunction, but its clinical significance on trauma patients is uncertain. Ketamine has emerged as an alternative for rapid sequence intubation induction. Among adult trauma patients intubated in the emergency department, we compare clinical outcomes among those induced with etomidate and ketamine.

Induction doses of etomidate during rapid sequence intubation cause transient adrenal dysfunction, but its clinical significance on trauma patients is uncertain. Ketamine has emerged as an alternative for rapid sequence intubation induction. Among adult trauma patients intubated in the emergency department, we compare clinical outcomes among those induced with etomidate and ketamine.

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