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Master of Public Health

Prostate size as a predictor of Gleason score upgrading in patients with low risk prostate cancer.

AUTHORS

Davies JD , Aghazadeh MA , Phillips S , Salem S , Chang SS , Clark PE , Cookson MS , Davis R , Herrell SD , Penson DF , Smith JA , Barocas DA , . The Journal of urology. 2011 12 ; 186(6). 2221-7

ABSTRACT

Gleason score upgrading between biopsy and surgical pathological specimens occurs in 30% to 50% of cases. Predicting upgrading in men with low risk prostate cancer may be particularly important since high grade disease influences management decisions and impacts prognosis. We determined whether prostate size predicts Gleason score upgrading in patients with low risk prostate cancer.

Gleason score upgrading between biopsy and surgical pathological specimens occurs in 30% to 50% of cases. Predicting upgrading in men with low risk prostate cancer may be particularly important since high grade disease influences management decisions and impacts prognosis. We determined whether prostate size predicts Gleason score upgrading in patients with low risk prostate cancer.

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