Statins and delirium during critical illness: a multicenter, prospective cohort study.
AUTHORS
Morandi
A ,
Hughes
CG ,
Thompson
JL ,
Pandharipande
PP ,
Shintani
AK ,
Vasilevskis
EE ,
Han
JH ,
Jackson
JC ,
Laskowitz
DT ,
Bernard
GR ,
Ely
EW ,
Girard
TD ,
. Critical care medicine. 2014 8 ; 42(8). 1899-909
- PMID: 24810528 [PubMed].
- PMCID: PMC4103957.
- NIHMSID: NIHMS578415
ABSTRACT
Since statins have pleiotropic effects on inflammation and coagulation that may interrupt delirium pathogenesis, we tested the hypotheses that statin exposure is associated with reduced delirium during critical illness, whereas discontinuation of statin therapy is associated with increased delirium.
Since statins have pleiotropic effects on inflammation and coagulation that may interrupt delirium pathogenesis, we tested the hypotheses that statin exposure is associated with reduced delirium during critical illness, whereas discontinuation of statin therapy is associated with increased delirium.
Tags: Published Thesis Products 2014