Karel G. M. Moons, PhD
Julius Center Research Program Methodology
Utrecht University, Netherlands
The course will introduce the principles of designing and analysing evidence-based clinical and translational research studies. Additionally, the course will cover the concept of causation versus prediction, the design of clinical (epidemiological) research, disease frequency and association measures, validity issues including confounding, and the generalizability of research to practice. Subsequently, in more detail, the course addresses the design and analysis of diagnostic, prognostic, therapeutic (focusing on randomised trials), and etiologic (side effects) research.