• Caprioli RM. Imaging Mass Spectrometry: Molecular Microscopy for Enabling a New Age of Discovery. Proteomics. 2014 Feb 4. PMID: 24497141 [PubMed].

Abstract 

The molecular expression from genomic, proteomic, and metabolomic processes ongoing in living cells is enormously complex, continuously challenging our ability to measure and understand their integrated totality. Important biological studies and advances in the understanding of the biochemistry and biology of living cells have most often been preceded by innovations in the technology used to probe cells, tissues, and animals that then facilitate new insightful observations. A great deal has been learned over the decades about individual enzymes and pathways from isolated samples and extracts from a wide variety of bacterial and animal sources and much progress has been made toward integrating these findings into a framework that describes the underlying biology. This article is protected by copyright. All rights reserved.

This article is protected by copyright. All rights reserved.