February 24, 2017
Posted in New Publications

MSTPublications: January & February 2017

Recently, we have had two Vanderbilt MSTP students publish first author manuscripts. An additional twelve MSTP students were co-authors or published a review article. Congratulations to all of our MSTP students on their successful publications in recent months! Take a look at the great work our students are doing.

 

First Author Original Research:

bair.pngHematopoietic Stem Cell Mobilization Is Necessary but Not Sufficient for Tolerance in Islet Transplantation.
Stocks BT
, Thomas AB, Elizer SK, Zhu Y, Marshall AF, Wilson CS, Moore DJ.
Diabetes. 2017 Jan;66(1):127-133. doi: 10.2337/db16-0444.

Achieving permanent organ graft tolerance in the absence of ongoing immune suppression remains the holy grail of transplant immunology. In this article, my lab and I found that transplant tolerance begins at the level of the Hematopoietic Stem Cell (HSC), a cell population whose mobilization during tolerogenic reprogramming required the presence of an intact sympathetic nervous system. Disruption of either HSC compartment or the sympathetic nervous system resulted in failure of graft tolerance to transplants. (by Blair Stocks, M3)

 

 

 

 

Alex.png

Validation of maternal recall of early pregnancy medication exposure using prospective diary data.
Sundermann ACHartmann KE, Jones SH, Torstenson ES, Velez Edwards DR.
Ann Epidemiol. 2017 Feb;27(2):135-139.e2. doi: 10.1016/j.annepidem.2016.11.015.

Research concerning exposure to over-the-counter medications during pregnancy often depends on maternal recall for assigning exposure status. The Right From the Start pregnancy cohort assessed NSAID use in early pregnancy through both prospective daily diaries and maternal recall at the end of the first trimester. If data collected in the daily diaries represents true medication use, relying on maternal recall would lead to exposure misclassification for over 25% of the study population. This suggests that the ability to effectively study the impact of drugs taken on an “as needed” basis during pregnancy may be jeopardized by relying on maternal recall and, therefore, prospective data collection methods should be prioritized. (by Alex Sundermann G2)

 

 

Co-authorships and Reviews:

Atypical rapid audio-visual temporal recalibration in autism spectrum disorders.
Noel JP,
De Niear MA, Stevenson R, Alais D, Wallace MT.
Autism Res. 2017 Jan;10(1):121-129. doi: 10.1002/aur.1633.

Comparative Transcriptome Profiles of Human Blood in Response to the Toll-like Receptor 4 Ligands Lipopolysaccharide and Monophosphoryl Lipid A.
​Luan L, Patil NK, Guo Y, Hernandez A, Bohannon JK, Fensterheim BA, Wang J, Xu Y, Enkhbaatar P, Stark R, Sherwood ER.
Sci Rep. 2017 Jan 5;7:40050. doi: 10.1038/srep40050.

Flt3 Ligand Treatment Attenuates T Cell Dysfunction and Improves Survival in a Murine Model of Burn Wound Sepsis.
​Patil NK, Bohannon JK, Luan L, Guo Y, Fensterheim B, Hernandez A, Wang J, Sherwood ER.
Shock. 2017 Jan;47(1):40-51.

IL-15 Enables Septic Shock by Maintaining NK Cell Integrity and Function.
Guo Y, Luan L, Patil NK, Wang J, Bohannon JK, Rabacal W,
Fensterheim BA, Hernandez A, Sherwood ER.
J Immunol. 2017 Feb 1;198(3):1320-1333. doi: 10.4049/jimmunol.1601486.

Influence of glioblastoma contact with the lateral ventricle on survival: a meta-analysis.
​Mistry AM, Hale AT, Chambless LB, Weaver KD, Thompson RC, Ihrie RA.
J Neurooncol. 2017 Jan;131(1):125-133. doi: 10.1007/s11060-016-2278-7.

Untangling ccRCC prognosis with SLINKY.
Reinfeld BI, Rathmell WK.
​Oncotarget. 2017 Feb 20. doi: 10.18632/oncotarget.15536. [Epub ahead of print] No abstract available.

Cost-utility of osteoarticular allograft versus endoprosthetic reconstruction for primary bone sarcoma of the knee: A markov analysis.
Wilson RJ, Sulieman LM,
VanHouten JP, Halpern JL, Schwartz HS, Devin CJ, Holt GE.
J Surg Oncol. 2017 Jan 20. doi: 10.1002/jso.24525. [Epub ahead of print]

Higher Charlson Comorbidity Index Scores Are Associated With Increased Hospital Length of Stay After Lower Extremity Orthopaedic Trauma.
​Lakomkin N, Kothari P, Dodd AC, VanHouten JP, Yarlagadda M, Collinge CA, Obremskey WT, Sethi MK.
J Orthop Trauma. 2017 Jan;31(1):21-26. doi: 10.1097/BOT.0000000000000701.

Cerebral hemodynamics and pseudo-continuous arterial spin labeling considerations in adults with sickle cell anemia.
Juttukonda MR, Jordan LC, Gindville MC, Davis LT,
Watchmaker JM, Pruthi S, Donahue MJ.
NMR Biomed. 2017 Feb;30(2). doi: 10.1002/nbm.3681.